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ONTOLOGY REPORT - ANNOTATIONS

Term:transport across blood-brain barrier
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Accession:GO:0150104 term browser browse the term
Definition:The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.
Synonyms:exact_synonym: transport across BBB
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa

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transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147 		JBrowse link
G LOC101978348 sodium/glucose cotransporter 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:1,467,787...1,535,135
Ensembl chrNW_004936755:1,467,787...1,535,042 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:5439721|PMID:20630619), (MGI:5754651|PMID:26619118) ARUK-UCL PMID:20630619 PMID:26619118 MGI:5439721 MGI:5754651 NCBI chrNW_004936646:1,326,900...1,407,236
Ensembl chrNW_004936646:1,327,374...1,406,456 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936683:803,186...910,143
Ensembl chrNW_004936683:803,134...910,284 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 involved_in ISO (MGI:6393124|PMID:14622120) ARUK-UCL PMID:14622120 MGI:6393124 NCBI chrNW_004936664:599,012...610,689
Ensembl chrNW_004936664:598,468...610,698 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 involved_in ISO (MGI:6437032|PMID:14595704) ARUK-UCL PMID:14595704 MGI:6437032 NCBI chrNW_004936647:2,774,063...2,798,585
Ensembl chrNW_004936647:2,773,768...2,798,511 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:1714544) ARUK-UCL
Ensembl		 PMID:1714544 GO_REF:0000107 NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:5,338,119...5,349,758
Ensembl chrNW_004936493:5,338,289...5,349,758 		JBrowse link
lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936810:791,823...838,303
Ensembl chrNW_004936810:758,182...838,365 		JBrowse link
G Fabp5 fatty acid binding protein 5 involved_in ISO (PMID:21395585) ARUK-UCL PMID:21395585 NCBI chrNW_004936656:2,881,552...2,886,192 JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:21,790,807...21,803,336
Ensembl chrNW_004936474:21,790,747...21,803,360 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:3,426,807...3,451,259
Ensembl chrNW_004936596:3,427,874...3,449,489 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:15,877,075...15,905,752
Ensembl chrNW_004936487:15,876,606...15,906,003
Ensembl chrNW_004936487:15,876,606...15,906,003 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
xenobiotic transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25053619 GO_REF:0000107 RGD:11252095 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 involved_in ISO PMID:12663688
PMID:17437408		 ARUK-UCL PMID:12663688 PMID:17437408 RGD:14929203 RGD:704399 NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15975
    localization 5183
      establishment of localization 4493
        transport 4194
          vascular transport 18
            transport across blood-brain barrier 17
              copper ion transport across blood-brain barrier 0
              lipid transport across blood-brain barrier + 6
              negative regulation of transport across blood-brain barrier + 1
              positive regulation of transport across blood-brain barrier + 1
              regulation of transport across blood-brain barrier + 1
              xenobiotic transport across blood-brain barrier 3
Path 2
Term Annotations click to browse term
  biological_process 15975
    multicellular organismal process 7395
      system process 2591
        circulatory system process 553
          vascular process in circulatory system 240
            vascular transport 18
              transport across blood-brain barrier 17
                copper ion transport across blood-brain barrier 0
                lipid transport across blood-brain barrier + 6
                negative regulation of transport across blood-brain barrier + 1
                positive regulation of transport across blood-brain barrier + 1
                regulation of transport across blood-brain barrier + 1
                xenobiotic transport across blood-brain barrier 3
paths to the root