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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium-dependent activation of synaptic vesicle fusion
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Accession:GO:0099502 term browser browse the term
Definition:The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.

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calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Doc2a double C2 domain alpha involved_in ISO PMID:22036572
(PMID:20150444)		 SynGO PMID:20150444 PMID:22036572 RGD:155230732 NCBI chrNW_004624782:13,217,553...13,221,763
Ensembl chrNW_004624782:13,217,736...13,221,457 		JBrowse link
G Doc2b double C2 domain beta involved_in ISO PMID:22036572
(PMID:20150444)		 SynGO PMID:20150444 PMID:22036572 RGD:155230732 NCBI chrNW_004624786:4,029,384...4,060,676
Ensembl chrNW_004624786:4,029,390...4,060,196 		JBrowse link
G Syt1 synaptotagmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624750:18,774,670...19,313,932
Ensembl chrNW_004624750:18,774,570...18,989,659 		JBrowse link
G Syt2 synaptotagmin 2 involved_in ISO (PMID:17192432) SynGO PMID:17192432 NCBI chrNW_004624807:8,103,665...8,201,567
Ensembl chrNW_004624807:8,160,431...8,196,916 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (PMID:24267651) SynGO PMID:24267651 NCBI chrNW_004624926:722,201...765,834
Ensembl chrNW_004624926:722,224...765,033 		JBrowse link
G Syt9 synaptotagmin 9 involved_in ISO (PMID:17521570) SynGO PMID:17521570 NCBI chrNW_004624817:8,996,880...9,171,226
Ensembl chrNW_004624817:8,996,893...9,166,331 		JBrowse link
regulation of calcium-dependent activation of synaptic vesicle fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1b calcium voltage-gated channel subunit alpha1 B involved_in ISO PMID:7832825 SynGO PMID:7832825 RGD:13792530 NCBI chrNW_004624760:78,754...257,901
Ensembl chrNW_004624760:81,236...257,787 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 involved_in ISO (PMID:25209271) SynGO PMID:25209271 NCBI chrNW_004624735:11,398,603...11,907,553
Ensembl chrNW_004624735:11,400,159...11,841,920 		JBrowse link
G Erc2 ELKS/RAB6-interacting/CAST family member 2 involved_in ISO (PMID:25209271) SynGO PMID:25209271 NCBI chrNW_004624822:756,532...1,806,129
Ensembl chrNW_004624822:756,550...1,807,175 		JBrowse link
G Prrt2 proline rich transmembrane protein 2 involved_in ISO (PMID:27052163) SynGO PMID:27052163 NCBI chrNW_004624782:13,390,347...13,393,775 JBrowse link
G Rimbp2 RIMS binding protein 2 involved_in ISO (PMID:27671655) SynGO PMID:27671655 NCBI chrNW_004624747:27,107,951...27,245,303
Ensembl chrNW_004624747:27,108,508...27,144,190 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISO (PMID:21241895) SynGO PMID:21241895 NCBI chrNW_004624763:20,027,601...20,567,288
Ensembl chrNW_004624763:20,027,574...20,567,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    localization 4970
      cellular localization 3323
        establishment of localization in cell 1959
          synaptic vesicle exocytosis 123
            calcium-dependent activation of synaptic vesicle fusion 12
              regulation of calcium-dependent activation of synaptic vesicle fusion 6
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10618
      regulation of biological process 10301
        signaling 5906
          cell-cell signaling 1285
            synaptic signaling 841
              trans-synaptic signaling 810
                anterograde trans-synaptic signaling 802
                  chemical synaptic transmission 802
                    neurotransmitter secretion 183
                      synaptic vesicle exocytosis 123
                        synaptic vesicle fusion to presynaptic active zone membrane 29
                          regulation of synaptic vesicle fusion to presynaptic active zone membrane 18
                            positive regulation of synaptic vesicle fusion to presynaptic active zone membrane 12
                              calcium-dependent activation of synaptic vesicle fusion 12
                                regulation of calcium-dependent activation of synaptic vesicle fusion 6
paths to the root