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ONTOLOGY REPORT - ANNOTATIONS

Term:MLL1 complex
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Accession:GO:0071339 term browser browse the term
Definition:A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.


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MLL1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash2l ASH2 like histone lysine methyltransferase complex subunit part_of
located_in		 ISO (MGI:4419079|PMID:15960975)
(PMID:23508102)		 RGD PMID:15960975 PMID:23508102 MGI:4419079 NCBI chr16:66,242,205...66,264,064
Ensembl chr16:66,242,212...66,264,061 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G C10h17orf49 similar to human chromosome 17 open reading frame 49 part_of ISO
IBA		 (PMID:15960975)
GO_REF:0000033		 RGD
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr10:54,951,991...54,954,756
Ensembl chr10:54,951,991...54,956,601 		JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 part_of ISO
ISS
IEA
IBA		 (PMID:15960975)
GO_REF:0000024
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:15960975 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr15:24,905,789...24,965,461
Ensembl chr15:24,905,789...24,951,285 		JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit located_in ISO (PMID:23508102) RGD PMID:23508102 NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432 		JBrowse link
G E2f6 E2F transcription factor 6 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683 		JBrowse link
G Hcfc1 host cell factor C1 part_of
located_in		 ISO
IEA		 (PMID:15960975)
(PMID:23508102)
GO_REF:0000107		 RGD
Ensembl		 PMID:15960975 PMID:23508102 GO_REF:0000107 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638 		JBrowse link
G Hcfc2 host cell factor C2 located_in
part_of		 ISO
IEA		 (PMID:23508102)
GO_REF:0000107		 RGD
Ensembl		 PMID:23508102 GO_REF:0000107 NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801 		JBrowse link
G Ino80c INO80 complex subunit C part_of ISS
ISO		 GO_REF:0000024
(PMID:15960975)		 UniProt
RGD		 PMID:15960975 GO_REF:0000024 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Kansl1 KAT8 regulatory NSL complex subunit 1 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr10:89,237,667...89,368,735
Ensembl chr10:89,237,667...89,366,951 		JBrowse link
G Kat8 lysine acetyltransferase 8 part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:15960975)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15960975 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:182,524,355...182,536,638
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Kmt2a lysine methyltransferase 2A part_of
located_in		 ISO (PMID:15960975)
(PMID:23508102)		 RGD PMID:15960975 PMID:23508102 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Las1l LAS1-like, ribosome biogenesis factor part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr  X:60,851,969...60,873,717
Ensembl chr  X:60,851,962...60,873,687 		JBrowse link
G Max MYC associated factor X part_of ISS
ISO		 GO_REF:0000024
(PMID:15960975)		 UniProt
RGD		 PMID:15960975 GO_REF:0000024 NCBI chr 6:95,636,859...95,662,204
Ensembl chr 6:95,636,858...95,662,137 		JBrowse link
G Mcrs1 microspherule protein 1 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Men1 menin 1 located_in
part_of		 ISO
IEA		 (PMID:23508102)
GO_REF:0000107		 RGD
Ensembl		 PMID:23508102 GO_REF:0000107 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mga MAX dimerization protein MGA part_of ISO
IBA		 (PMID:15960975)
GO_REF:0000033		 RGD
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr 3:106,851,216...106,942,908
Ensembl chr 3:106,851,140...106,941,043 		JBrowse link
G Pelp1 proline, glutamate and leucine rich protein 1 part_of ISS
ISO		 GO_REF:0000024
(PMID:15960975)		 UniProt
RGD		 PMID:15960975 GO_REF:0000024 NCBI chr10:55,094,798...55,111,833
Ensembl chr10:55,094,796...55,111,994 		JBrowse link
G Phf20 PHD finger protein 20 part_of ISO
IBA		 (PMID:15960975)
GO_REF:0000033		 RGD
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr 3:144,710,253...144,816,696
Ensembl chr 3:144,710,353...144,814,439 		JBrowse link
G Prpf31 pre-mRNA processing factor 31 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr 1:65,575,887...65,587,561
Ensembl chr 1:65,575,887...65,587,873 		JBrowse link
G Rbbp5 RB binding protein 5, histone lysine methyltransferase complex subunit part_of
located_in		 ISO (PMID:15960975)
(PMID:23508102)		 RGD PMID:15960975 PMID:23508102 NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107 		JBrowse link
G Rnasek ribonuclease K part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,954,904...54,956,622
Ensembl chr10:54,951,991...54,956,601 		JBrowse link
G Rnf2 ring finger protein 2 part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:15960975)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15960975 GO_REF:0000024 GO_REF:0000107 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 part_of ISO
ISS		 (PMID:15960975)
GO_REF:0000024		 RGD
UniProt		 PMID:15960975 GO_REF:0000024 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Senp3 SUMO specific peptidase 3 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Taf4 TATA-box binding protein associated factor 4 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr 3:167,017,992...167,083,413
Ensembl chr 3:167,017,993...167,083,356 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 part_of ISO
ISS
IEA		 (PMID:15960975)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15960975 GO_REF:0000024 GO_REF:0000107 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 part_of ISO (PMID:15960975) RGD PMID:15960975 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:15960975)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15960975 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tex10 testis expressed 10 part_of ISO
IBA		 (PMID:15960975)
GO_REF:0000033		 RGD
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr 5:62,762,230...62,808,373
Ensembl chr 5:62,762,230...62,808,373 		JBrowse link
G Wdr5 WD repeat domain 5 part_of
located_in		 ISO
ISS
IEA		 (PMID:15960975)
GO_REF:0000024
(PMID:23508102)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15960975 PMID:23508102 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20629
    protein-containing complex 6604
      nuclear protein-containing complex 1276
        histone methyltransferase complex 71
          MLL1/2 complex 34
            MLL1 complex 33
Path 2
Term Annotations click to browse term
  cellular_component 20629
    cellular anatomical entity 20391
      organelle 13803
        intracellular organelle 13394
          intracellular membrane-bounded organelle 11846
            nucleus 7395
              nuclear lumen 4027
                nucleoplasm 3535
                  histone methyltransferase complex 71
                    MLL1/2 complex 34
                      MLL1 complex 33
paths to the root