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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition

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positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC11 anaphase promoting complex subunit 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:73,765,660...73,773,687
Ensembl chr16:73,765,674...73,773,620 		JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:116,680,799...116,728,065
Ensembl chr11:116,680,587...116,728,122 		JBrowse link
G ANAPC7 anaphase promoting complex subunit 7 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr11:105,616,942...105,640,144 JBrowse link
G CDC16 cell division cycle 16 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:92,018,619...92,057,232
Ensembl chr 3:92,018,681...92,059,413 		JBrowse link
G CDC20 cell division cycle 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:89,449,008...89,453,263
Ensembl chr20:89,444,165...89,453,044 		JBrowse link
G CDC23 cell division cycle 23 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:40,858,185...40,892,409
Ensembl chr23:40,855,362...40,892,385 		JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 7:51,212,266...51,300,153 JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:110,425,895...110,541,431
Ensembl chr10:110,425,076...110,541,538 		JBrowse link
G NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:119,679,090...119,949,212
Ensembl chr 8:119,691,106...119,949,587 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO (PMID:20551165) BHF-UCL PMID:20551165 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C involved_in ISO (PMID:12629039) UniProt PMID:12629039 NCBI chr 2:18,069,525...18,073,597 JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078 		JBrowse link
G MAD2L1BP MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,524,122...28,529,162
Ensembl chr17:28,524,117...28,529,139 		JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chr26:53,195,600...53,201,846 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    cellular process 15870
      cell cycle process 1306
        positive regulation of cell cycle process 288
          positive regulation of mitotic nuclear division 48
            positive regulation of mitotic metaphase/anaphase transition 14
              negative regulation of mitotic spindle assembly checkpoint signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 16925
    cellular process 15870
      cellular component organization or biogenesis 6767
        cellular component organization 6531
          organelle organization 3670
            organelle fission 532
              nuclear division 479
                mitotic nuclear division 284
                  mitotic sister chromatid segregation 192
                    mitotic sister chromatid separation 55
                      regulation of mitotic sister chromatid separation 52
                        positive regulation of mitotic sister chromatid separation 14
                          positive regulation of mitotic metaphase/anaphase transition 14
                            negative regulation of mitotic spindle assembly checkpoint signaling + 3
paths to the root