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ONTOLOGY REPORT - ANNOTATIONS

Term:MLL1/2 complex
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Accession:GO:0044665 term browser browse the term
Definition:A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.
Synonyms:exact_synonym: Trx-containing complex


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MLL1/2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASH2L ASH2 like, histone lysine methyltransferase complex subunit located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr 8:38,105,493...38,140,080
Ensembl chr 8:38,105,493...38,144,076 		JBrowse link
G DPY30 dpy-30 histone methyltransferase complex regulatory subunit located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr 2:32,011,649...32,039,835
Ensembl chr 2:31,867,809...32,039,805 		JBrowse link
G HCFC1 host cell factor C1 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr  X:153,947,557...153,971,818
Ensembl chr  X:153,947,557...153,971,818 		JBrowse link
G HCFC2 host cell factor C2 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr12:104,064,531...104,106,524
Ensembl chr12:104,064,531...104,106,524 		JBrowse link
G KMT2B lysine methyltransferase 2B located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr19:35,718,003...35,738,878
Ensembl chr19:35,717,973...35,738,880 		JBrowse link
G MEN1 menin 1 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr 1:205,086,142...205,121,978
Ensembl chr 1:205,086,142...205,122,015 		JBrowse link
G WDR5 WD repeat domain 5 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr 9:134,135,199...134,159,968
Ensembl chr 9:134,135,365...134,159,968 		JBrowse link
MLL1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASH2L ASH2 like, histone lysine methyltransferase complex subunit located_in
part_of		 IPI
IEA		 (PMID:23508102) ComplexPortal
Ensembl		 PMID:23508102 GO_REF:0000107 NCBI chr 8:38,105,493...38,140,080
Ensembl chr 8:38,105,493...38,144,076 		JBrowse link
G C17orf49 chromosome 17 open reading frame 49 part_of IDA
IBA		 (PMID:15960975) UniProt
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr17:7,014,782...7,017,520
Ensembl chr17:7,014,495...7,017,525 		JBrowse link
G CHD8 chromodomain helicase DNA binding protein 8 part_of IDA
IBA
IEA		 (PMID:15960975) UniProt
GO_Central		 PMID:15960975 GO_REF:0000033 GO_REF:0000104 NCBI chr14:21,385,199...21,456,123
Ensembl chr14:21,385,194...21,456,126 		JBrowse link
G DPY30 dpy-30 histone methyltransferase complex regulatory subunit located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr 2:32,011,649...32,039,835
Ensembl chr 2:31,867,809...32,039,805 		JBrowse link
G E2F6 E2F transcription factor 6 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 2:11,444,375...11,466,161
Ensembl chr 2:11,444,375...11,466,177 		JBrowse link
G HCFC1 host cell factor C1 part_of
located_in		 IDA
IPI		 (PMID:15960975)
(PMID:23508102)		 UniProt
ComplexPortal		 PMID:15960975 PMID:23508102 NCBI chr  X:153,947,557...153,971,818
Ensembl chr  X:153,947,557...153,971,818 		JBrowse link
G HCFC2 host cell factor C2 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr12:104,064,531...104,106,524
Ensembl chr12:104,064,531...104,106,524 		JBrowse link
G INO80C INO80 complex subunit C part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr18:35,468,333...35,497,960
Ensembl chr18:35,452,230...35,497,979 		JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr17:46,029,916...46,225,367
Ensembl chr17:46,029,916...46,225,389 		JBrowse link
G KAT8 lysine acetyltransferase 8 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr16:31,117,664...31,131,393
Ensembl chr16:31,114,489...31,131,393 		JBrowse link
G KMT2A lysine methyltransferase 2A part_of
located_in		 IDA
IPI		 (PMID:15960975)
(PMID:23508102)		 UniProt
ComplexPortal		 PMID:15960975 PMID:23508102 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832 		JBrowse link
G LAS1L LAS1 like ribosome biogenesis factor part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr  X:65,512,582...65,534,787
Ensembl chr  X:65,438,549...65,534,810 		JBrowse link
G MAX MYC associated factor X part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr14:65,006,101...65,102,695
Ensembl chr14:65,006,174...65,102,695 		JBrowse link
G MCRS1 microspherule protein 1 part_of IDA
IEA		 (PMID:15960975) UniProt
InterPro		 PMID:15960975 GO_REF:0000002 NCBI chr12:49,558,299...49,568,142
Ensembl chr12:49,556,544...49,568,145 		JBrowse link
G MEN1 menin 1 located_in IPI (PMID:23508102) ComplexPortal PMID:23508102 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MGA MAX dimerization protein MGA part_of IDA
IBA
IEA		 (PMID:15960975) UniProt
GO_Central
InterPro		 PMID:15960975 GO_REF:0000002 GO_REF:0000033 NCBI chr15:41,621,224...41,769,940
Ensembl chr15:41,621,134...41,773,081 		JBrowse link
G PELP1 proline, glutamate and leucine rich protein 1 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr17:4,669,774...4,704,137
Ensembl chr17:4,669,774...4,704,337 		JBrowse link
G PHF20 PHD finger protein 20 part_of IDA
IBA		 (PMID:15960975) UniProt
GO_Central		 PMID:15960975 GO_REF:0000033 NCBI chr20:35,772,015...35,950,370
Ensembl chr20:35,771,974...35,950,370 		JBrowse link
G PRPF31 pre-mRNA processing factor 31 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr19:54,115,754...54,131,713
Ensembl chr19:54,115,410...54,131,719 		JBrowse link
G RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit part_of
located_in		 IDA
IPI		 (PMID:15960975)
(PMID:23508102)		 UniProt
ComplexPortal		 PMID:15960975 PMID:23508102 NCBI chr 1:205,086,142...205,121,978
Ensembl chr 1:205,086,142...205,122,015 		JBrowse link
G RNF2 ring finger protein 2 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 1:185,045,558...185,102,603
Ensembl chr 1:185,045,497...185,102,603 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 3:128,064,785...128,153,914
Ensembl chr 3:128,064,778...128,153,914 		JBrowse link
G RUVBL2 RuvB like AAA ATPase 2 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr19:48,993,448...49,015,995
Ensembl chr19:48,993,562...49,015,970 		JBrowse link
G SENP3 SUMO specific peptidase 3 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr17:7,561,919...7,571,969
Ensembl chr17:7,561,919...7,571,969 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr  X:71,366,357...71,530,525
Ensembl chr  X:71,366,136...71,532,374 		JBrowse link
G TAF4 TATA-box binding protein associated factor 4 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr20:61,974,798...62,065,881
Ensembl chr20:61,953,469...62,065,881 		JBrowse link
G TAF6 TATA-box binding protein associated factor 6 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 7:100,107,070...100,127,171
Ensembl chr 7:100,106,876...100,119,841 		JBrowse link
G TAF7 TATA-box binding protein associated factor 7 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 5:141,318,490...141,320,784
Ensembl chr 5:141,259,884...141,320,784 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 part_of IDA (PMID:15960975) UniProt PMID:15960975 NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,362,026...69,370,013 		JBrowse link
G TEX10 testis expressed 10 part_of IDA
IBA
IEA		 (PMID:15960975) UniProt
GO_Central
TreeGrafter		 PMID:15960975 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:100,302,084...100,352,942
Ensembl chr 9:100,302,077...100,352,942 		JBrowse link
G WDR5 WD repeat domain 5 located_in
part_of		 IPI
IDA		 (PMID:23508102)
(PMID:15960975)		 ComplexPortal
UniProt		 PMID:15960975 PMID:23508102 NCBI chr 9:134,135,199...134,159,968
Ensembl chr 9:134,135,365...134,159,968 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20717
    protein-containing complex 7461
      nuclear protein-containing complex 1432
        histone methyltransferase complex 74
          MLL1/2 complex 32
            MLL1 complex 31
Path 2
Term Annotations click to browse term
  cellular_component 20717
    cellular anatomical entity 20331
      organelle 15528
        intracellular organelle 14561
          intracellular membrane-bounded organelle 13372
            nucleus 8620
              nuclear lumen 5177
                nucleoplasm 4307
                  histone methyltransferase complex 74
                    MLL1/2 complex 32
                      MLL1 complex 31
paths to the root