HCFC1 (host cell factor C1 (VP16-accessory protein))

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Keyword

Gene: HCFC1 (host cell factor C1 (VP16-accessory protein)) Homo sapiens

Symbol:

HCFC1

Name:

host cell factor C1 (VP16-accessory protein)

Description:

This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

C1 factor; CFF; HCF; HCF-1; HCF1; HFC1; host cell factor 1; MGC70925; MRX3; OTTHUMP00000025995; OTTHUMP00000025997; VCAF; VP16 accessory protein

Orthologs:

Mus musculus : Hcfc1 (host cell factor C1) MGI
Rattus norvegicus : Hcfc1 (host cell factor C1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	X	153,081,072 - 153,104,978	-	NCBI
Human Genome Assembly HuRef	X	141,865,579 - 141,889,655	-	NCBI
Human Genome Assembly GRCh37	X	153,213,008 - 153,236,819	-	NCBI
Human Genome Assembly Build 36	X	152,866,202 - 152,890,013	-	NCBI
Human Cytogenetic Map	X	q28		NCBI
Human Genome Assembly	X	152,733,854 - 152,751,024		NCBI