Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:histone H4K20 methyltransferase activity
go back to main search page
Accession:GO:0042799 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.
Comment:Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies.
Synonyms:exact_synonym: histone H4 lysine 20-specific methyltransferase activity;   histone H4K20 methylase activity;   histone H4K20 methylation;   histone lysine N-methyltransferase activity (H4-K20 specific);   histone methylase activity (H4-K20 specific);   histone methyltransferase activity (H4-K20 specific)
 xref: reactome:R-HSA-2301205 "SETD8 monomethylates histone H4";   reactome:R-HSA-5682965 "WHSC1 dimethylates histone H4 on lysine K21 at DSBs"


show annotations for term's descendants           Sort by:
histone H4K20 methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G ENSRNOG00000067141 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:31,086,733...31,087,921 JBrowse link
G Kmt5a lysine methyltransferase 5A enables ISO
IBA		 (PMID:27338793)
GO_REF:0000033		 RGD
GO_Central		 PMID:27338793 GO_REF:0000033 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Kmt5al2 lysine methyltransferase 5A like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Kmt5b lysine methyltransferase 5B enables ISS
ISO
IBA
IEA		 GO_REF:0000024
(MGI:5575440|PMID:24049080), (PMID:15145825)
GO_REF:0000033
GO_REF:0000117
(PMID:24396869), (PMID:28114273)		 UniProt
RGD
GO_Central		 PMID:15145825 PMID:24049080 PMID:24396869 PMID:28114273 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 MGI:5575440 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C enables ISO
IBA
ISS		 (PMID:24049080), (PMID:24396869), (PMID:28114273)
(PMID:15145825), (PMID:25335925)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:15145825 PMID:24049080 PMID:24396869 PMID:25335925 PMID:28114273 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 enables ISO (MGI:2664413|PMID:12805229) RGD PMID:12805229 MGI:2664413 NCBI chr17:9,311,963...9,426,373
Ensembl chr17:9,315,237...9,425,358 		JBrowse link
G Setd4 SET domain containing 4 enables ISO (PMID:31308046) RGD PMID:31308046 NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243 		JBrowse link
G Smyd5 SMYD family member 5 enables ISO
IBA		 (MGI:6709288|PMID:28250819), (MGI:6716956|PMID:22921934)
GO_REF:0000033		 RGD
GO_Central		 PMID:22921934 PMID:28250819 GO_REF:0000033 MGI:6709288 MGI:6716956 NCBI chr 4:117,969,615...117,984,082
Ensembl chr 4:117,969,626...117,984,347 		JBrowse link
histone H4K20 monomethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G Kmt5a lysine methyltransferase 5A enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Kmt5al2 lysine methyltransferase 5A like 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Kmt5b lysine methyltransferase 5B enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Prdm9 PR/SET domain 9 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652 		JBrowse link
histone H4K20 trimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttll12 tubulin tyrosine ligase like 12 NOT|enables ISO (PMID:23251473) RGD PMID:23251473 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
histone H4K20me methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmt5b lysine methyltransferase 5B enables IEA GO_REF:0000116
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Prdm9 PR/SET domain 9 enables IEA GO_REF:0000116
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      catalytic activity, acting on a protein 2444
        protein methyltransferase activity 106
          protein-lysine N-methyltransferase activity 67
            histone H4K20 methyltransferase activity 12
              histone H4K20 monomethyltransferase activity 7
              histone H4K20 trimethyltransferase activity 1
              histone H4K20me methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      transferase activity 2386
        transferase activity, transferring one-carbon groups 218
          methyltransferase activity 208
            S-adenosylmethionine-dependent methyltransferase activity 167
              lysine N-methyltransferase activity 67
                protein-lysine N-methyltransferase activity 67
                  histone H4K20 methyltransferase activity 12
                    histone H4K20 monomethyltransferase activity 7
                    histone H4K20 trimethyltransferase activity 1
                    histone H4K20me methyltransferase activity 3
paths to the root