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ONTOLOGY REPORT - ANNOTATIONS

Term:death receptor agonist activity
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Accession:GO:0038177 term browser browse the term
Definition:Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.
Synonyms:exact_synonym: death receptor activator activity


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death receptor agonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eda ectodysplasin-A enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:99,019,212...99,444,366
Ensembl chr  X:99,019,212...99,444,368 		JBrowse link
G Hspa1a heat shock protein 1A enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B enables ISO (PMID:26183779) UniProt PMID:26183779 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Ngf nerve growth factor enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329 		JBrowse link
G Tnf tumor necrosis factor enables ISO
IDA		 (PMID:14985352) MGI PMID:14985352 GO_REF:0000119 MGI:4834177 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
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  molecular_function 28831
    binding 17526
      protein binding 14890
        signaling receptor binding 1682
          receptor ligand activity 550
            death receptor agonist activity 5
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