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ONTOLOGY REPORT - ANNOTATIONS

Term:procollagen-proline 4-dioxygenase complex
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Accession:GO:0016222 term browser browse the term
Definition:A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
Synonyms:broad_synonym: prolyl 4-hydroxylase complex
 related_synonym: procollagen-proline, 2-oxoglutarate-4-dioxygenase complex


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procollagen-proline 4-dioxygenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide part_of IDA (PMID:7753822) MGI PMID:7753822 NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126 		JBrowse link
G P4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide part_of IDA (PMID:7753822) MGI PMID:7753822 NCBI chr11:53,991,750...54,022,494
Ensembl chr11:53,990,921...54,022,491 		JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide part_of ISO MGI GO_REF:0000008 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28585
    protein-containing complex 6180
      endoplasmic reticulum protein-containing complex 133
        procollagen-proline 4-dioxygenase complex 3
          procollagen-proline 4-dioxygenase complex, alpha(I) type 0
          procollagen-proline 4-dioxygenase complex, alpha(II) type 0
          procollagen-proline 4-dioxygenase complex, alpha(III) type 0
Path 2
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19620
      organelle 13555
        membrane-bounded organelle 12560
          intracellular membrane-bounded organelle 12012
            endoplasmic reticulum 1941
              endoplasmic reticulum protein-containing complex 133
                procollagen-proline 4-dioxygenase complex 3
                  procollagen-proline 4-dioxygenase complex, alpha(I) type 0
                  procollagen-proline 4-dioxygenase complex, alpha(II) type 0
                  procollagen-proline 4-dioxygenase complex, alpha(III) type 0
paths to the root