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ONTOLOGY REPORT - ANNOTATIONS


Term:chloride:monoatomic cation symporter activity
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Accession:GO:0015377 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).
Synonyms:broad_synonym: cation:chloride cotransporter activity;   cation:chloride symporter activity
 xref: TC:2.A.30



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chloride:monoatomic cation symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a1 solute carrier family 12 member 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc12a2 solute carrier family 12 member 2 enables TAS
ISO
(PMID:7629105) RGD PMID:7629105 PMID:10393355 RGD:634054 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc12a7 solute carrier family 12 member 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
JBrowse link
G Slc12a8 solute carrier family 12, member 8 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834
JBrowse link
G Slc12a9 solute carrier family 12, member 9 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877
JBrowse link
dopamine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:9776363 RGD:1643122 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a3 solute carrier family 22 member 3 IDA RGD PMID:9830022 RGD:1643215 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc6a2 solute carrier family 6 member 2 enables ISO
IBA
(PMID:11093780), (PMID:8125921)
GO_REF:0000033
RGD
GO_Central
PMID:8125921 PMID:11093780 GO_REF:0000033 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 enables IDA
ISO
IBA
IMP
MGI:2386303 (MGI:1340648|PMID:10375632), (PMID:9520487)
GO_REF:0000033
PMID:1948034
PMID:1502198
(PMID:10375632), (PMID:11093780), (PMID:1406597), (PMID:15505207), (PMID:19478460), (PMID:8302271)
PMID:8125921
PMID:1948035
RGD
GO_Central
PMID:1406597 PMID:8302271 PMID:9520487 PMID:10375632 PMID:11093780 More... GO_REF:0000033 MGI:1340648, RGD:730166, RGD:730247, RGD:152995550, RGD:152995566, RGD:730214, RGD:4139887 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
gamma-aminobutyric acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a1 solute carrier family 6 member 1 enables IDA
IBA
ISO
GO_REF:0000033
(MGI:52213|PMID:8420981), (MGI:7275316|PMID:30270321), (MGI:7275321|PMID:16150932)
PMID:18054861
PMID:21775701
(PMID:10973981), (PMID:30132828)
GO_Central
RGD
PMID:8420981 PMID:10973981 PMID:16150932 PMID:30132828 PMID:30270321 More... GO_REF:0000033 MGI:52213 MGI:7275316 MGI:7275321, RGD:632739, RGD:152025510, RGD:152025506 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc6a11 solute carrier family 6 member 11 enables IDA
IBA
ISO
GO_REF:0000033
(MGI:52213|PMID:8420981), (MGI:7275316|PMID:30270321)
(PMID:7874447)
PMID:1497897
GO_Central
RGD
PMID:7874447 PMID:8420981 PMID:30270321 PMID:1400419 PMID:1497897 GO_REF:0000033 MGI:52213 MGI:7275316, RGD:727560, RGD:729938 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443
JBrowse link
G Slc6a12 solute carrier family 6 member 12 enables TAS
IBA
ISO
ISS
IEA
GO_REF:0000033
(MGI:50760|PMID:1517200)
GO_REF:0000024
(PMID:10358010)
(PMID:7589472), (PMID:7861179)
GO_REF:0000002
GO_Central
RGD
UniProt
InterPro
PMID:1517200 PMID:7589472 PMID:7861179 PMID:10358010 PMID:15073174 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:50760, RGD:1303365 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750
JBrowse link
G Slc6a13 solute carrier family 6 member 13 enables IDA
IBA
ISO
IEA
GO_REF:0000033
(MGI:52213|PMID:8420981), (MGI:5462132|PMID:22896705), (MGI:7275316|PMID:30270321)
(PMID:17502375), (PMID:22932902)
GO_REF:0000107
GO_REF:0000002
GO_Central
RGD
Ensembl
InterPro
PMID:8420981 PMID:17502375 PMID:22896705 PMID:22932902 PMID:30270321 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 MGI:52213 MGI:5462132 MGI:7275316, RGD:727560, RGD:152025533 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
JBrowse link
G Slc6a6 solute carrier family 6 member 6 enables IEA
IBA
ISO
IDA
GO_REF:0000107
GO_REF:0000033
(MGI:7275316|PMID:30270321)
PMID:18501699
Ensembl
GO_Central
RGD
PMID:30270321 PMID:18501699 GO_REF:0000033 GO_REF:0000107 MGI:7275316, RGD:30309916 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slc6a8 solute carrier family 6 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979
JBrowse link
neutral L-amino acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a18 solute carrier family 6 member 18 enables ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5913069|PMID:19478081), (MGI:6120366|PMID:26240152), (MGI:7408278|PMID:20377526)
UniProt
Ensembl
RGD
PMID:19478081 PMID:20377526 PMID:26240152 GO_REF:0000024 GO_REF:0000107 MGI:5913069 MGI:6120366 MGI:7408278 NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925
JBrowse link
norepinephrine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:9776363 RGD:1643122 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc6a2 solute carrier family 6 member 2 enables IDA
IBA
ISO
GO_REF:0000033
(MGI:3834965|PMID:16269905)
(PMID:2008212), (PMID:8125921)
GO_Central
RGD
PMID:2008212 PMID:8125921 PMID:16269905 PMID:10196144 GO_REF:0000033 MGI:3834965, RGD:634151 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 enables IDA
IBA
PMID:8125921
GO_REF:0000033
GO_Central PMID:8125921 GO_REF:0000033, RGD:152995566 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a4 solute carrier family 12 member 4 enables IEA
ISO
ISS
IBA
GO_REF:0000002
(PMID:34031912)
GO_REF:0000024
(MGI:7327240|PMID:11551954)
GO_REF:0000033
InterPro
RGD
UniProt
GO_Central
PMID:11551954 PMID:34031912 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:7327240 NCBI chr19:33,838,418...33,860,369
Ensembl chr19:33,838,419...33,860,331
JBrowse link
G Slc12a5 solute carrier family 12 member 5 enables IDA
ISO
IBA
IEA
MGI:2181025 (PMID:11395011)
GO_REF:0000033
PMID:22544747
GO_REF:0000002
PMID:11551954
GO_REF:0000107
(PMID:12106695)
RGD
GO_Central
InterPro
Ensembl
PMID:11395011 PMID:12106695 PMID:12040048 PMID:22544747 PMID:11551954 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:628350, RGD:329845507, RGD:153298944, RGD:2303952, RGD:2303821, RGD:2303818 NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765
JBrowse link
G Slc12a6 solute carrier family 12, member 6 enables ISO
IBA
(PMID:10187864), (PMID:10600773), (PMID:11551954), (PMID:16048901), (PMID:19665974), (PMID:34031912)
GO_REF:0000033
(MGI:1337957|PMID:10347194), (MGI:7484282|PMID:31649201)
RGD
GO_Central
PMID:10187864 PMID:10347194 PMID:10600773 PMID:11551954 PMID:16048901 More... GO_REF:0000033 MGI:1337957 MGI:7484282 NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258
JBrowse link
G Slc12a7 solute carrier family 12 member 7 enables TAS
IBA
IEA
ISO
ISS
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107
(MGI:2384257|PMID:12106695), (MGI:7327240|PMID:11551954)
GO_REF:0000024
GO_Central
InterPro
Ensembl
RGD
UniProt
PMID:11551954 PMID:12106695 PMID:15533301 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:2384257 MGI:7327240, RGD:1558104 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
JBrowse link
G Slc12a8 solute carrier family 12, member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834
JBrowse link
G Slc12a9 solute carrier family 12, member 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877
JBrowse link
serotonin:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 enables IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:16926160 GO_REF:0000033, RGD:5130998 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
JBrowse link
G Slc18a2 solute carrier family 18 member A2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables TAS
IBA
ISO
IDA
IMP
GO_REF:0000033
(MGI:85054|PMID:9037532)
(PMID:10407194), (PMID:12869649), (PMID:17506858), (PMID:8987735)
PMID:1944572
PMID:15627510
PMID:8601815
PMID:10716733
PMID:11709063
GO_Central
RGD
PMID:8987735 PMID:9037532 PMID:10407194 PMID:12869649 PMID:17506858 More... GO_REF:0000033 MGI:85054, RGD:730261, RGD:155663539, RGD:155663546, RGD:8553308, RGD:155663514, RGD:8554226, RGD:8553990, RGD:1580635 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a3 solute carrier family 12 member 3 enables IMP
IDA
ISO
IEA
PMID:10894798
(MGI:7388220|PMID:15068971)
(PMID:18270262), (PMID:36351028), (PMID:36792826)
GO_REF:0000107
RGD
Ensembl
PMID:15068971 PMID:18270262 PMID:36351028 PMID:36792826 PMID:8021284 More... GO_REF:0000107 MGI:7388220, RGD:69999, RGD:1624221, RGD:155663524 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091
JBrowse link
G Slc6a1 solute carrier family 6 member 1 enables ISO (PMID:10973981) RGD PMID:10973981 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
sodium:potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a1 solute carrier family 12 member 1 enables IDA
ISO
IEA
IBA
(MGI:2177364|PMID:11790783)
GO_REF:0000107
(PMID:21321328)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:11790783 PMID:21321328 PMID:16291577 GO_REF:0000033 GO_REF:0000107 MGI:2177364, RGD:1624189 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc12a2 solute carrier family 12 member 2 enables IMP
IBA
ISO
GO_REF:0000033
(PMID:33597714)
GO_Central
RGD
PMID:33597714 PMID:12556450 GO_REF:0000033, RGD:1580435 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc12a3 solute carrier family 12 member 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        monoatomic ion transmembrane transporter activity 759
          monoatomic anion transmembrane transporter activity 148
            chloride transmembrane transporter activity 120
              chloride:monoatomic cation symporter activity 23
                potassium:chloride symporter activity + 9
                sodium:chloride symporter activity + 17
Path 2
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        active transmembrane transporter activity 444
          secondary active transmembrane transporter activity 289
            symporter activity 139
              solute:monoatomic cation symporter activity 113
                monoatomic anion:monoatomic cation symporter activity 26
                  chloride:monoatomic cation symporter activity 23
                    potassium:chloride symporter activity + 9
                    sodium:chloride symporter activity + 17
paths to the root