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ONTOLOGY REPORT - ANNOTATIONS


Term:bile acid:sodium symporter activity
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Accession:GO:0008508 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).
Synonyms:xref: Reactome:R-HSA-194121 "SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol";   reactome:R-HSA-194187 "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol";   reactome:R-HSA-433089 "SOAT can transport taurolithocholate-3-sulphate"



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bile acid:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc10a1 solute carrier family 10 member 1 enables TAS
IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12105223 PMID:1961729 GO_REF:0000033, RGD:625479, RGD:729835 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc10a2 solute carrier family 10 member 2 enables TAS
IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11509565 PMID:8770054 GO_REF:0000033, RGD:628456, RGD:729802 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc10a3 solute carrier family 10, member 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:152,154,757...152,158,563
Ensembl chr  X:152,151,076...152,162,958
JBrowse link
G Slc10a4 solute carrier family 10, member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:35,198,149...35,203,863
Ensembl chr14:35,197,886...35,203,729
JBrowse link
G Slc10a5 solute carrier family 10, member 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:91,457,540...91,458,844
Ensembl chr 2:91,444,454...91,489,651
JBrowse link
G Slc10a6 solute carrier family 10 member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      lipid transporter activity 171
        lipid transmembrane transporter activity 55
          bile acid transmembrane transporter activity 21
            bile acid:sodium symporter activity 6
Path 2
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        active transmembrane transporter activity 444
          secondary active transmembrane transporter activity 289
            symporter activity 139
              solute:monoatomic cation symporter activity 113
                solute:sodium symporter activity 81
                  organic acid:sodium symporter activity 35
                    monocarboxylate:sodium symporter activity 14
                      bile acid:sodium symporter activity 6
paths to the root