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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial respiratory chain complex I
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Accession:GO:0005747 term browser browse the term
Definition:A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Synonyms:alt_id: GO:0005748
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces;   NCBITaxon:4930 ! Saccharomyces


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mitochondrial respiratory chain complex I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmac1 distal membrane arm assembly complex 1 part_of
located_in		 ISO (PMID:27626371) MGI
UniProt		 PMID:27626371 GO_REF:0000119 MGI:4834177 NCBI chr 4:75,195,588...75,196,529
Ensembl chr 4:75,195,591...75,196,542 		JBrowse link
G Dmac2 distal membrane arm assembly complex 2 part_of
located_in		 ISO (PMID:27626371) MGI
UniProt		 PMID:27626371 GO_REF:0000119 MGI:4834177 NCBI chr 7:25,318,839...25,324,975
Ensembl chr 7:25,318,839...25,324,976 		JBrowse link
G Foxred1 FAD-dependent oxidoreductase domain containing 1 part_of
located_in		 ISO (PMID:25678554) MGI
UniProt		 PMID:25678554 GO_REF:0000119 MGI:4834177 NCBI chr 9:35,115,504...35,122,499
Ensembl chr 9:35,115,502...35,122,351 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G mt-Nd2 NADH dehydrogenase 2, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:3,914...4,951
Ensembl chr MT:3,914...4,951 		JBrowse link
G mt-Nd3 NADH dehydrogenase 3, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:9,459...9,806
Ensembl chr MT:9,459...9,806 		JBrowse link
G mt-Nd4 NADH dehydrogenase 4, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:10,167...11,544
Ensembl chr MT:10,167...11,544 		JBrowse link
G mt-Nd4l NADH dehydrogenase 4L, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:9,877...10,173
Ensembl chr MT:9,877...10,173 		JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565 		JBrowse link
G mt-Nd6 NADH dehydrogenase 6, mitochondrial part_of
located_in		 ISO (PMID:28844695) MGI
ComplexPortal		 PMID:28844695 GO_REF:0000119 MGI:4834177 NCBI chr MT:13,552...14,070
Ensembl chr MT:13,552...14,070 		JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:36,451,241...36,454,891
Ensembl chr  X:36,451,241...36,454,816 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:92,367,208...92,401,547
Ensembl chr 1:92,366,732...92,401,582 		JBrowse link
G Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:57,024,762...57,031,248
Ensembl chr17:57,024,767...57,029,141 		JBrowse link
G Ndufa11b NADH:ubiquinone oxidoreductase subunit A11B part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:21,872,437...21,873,103
Ensembl chr16:21,872,260...21,872,683 		JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:94,034,897...94,057,302
Ensembl chr10:94,034,582...94,057,305 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:70,346,813...70,355,208
Ensembl chr 8:70,346,830...70,355,208 		JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 part_of
located_in		 ISO
IBA
TAS		 (PMID:10318868)
(PMID:28844695)		 MGI
GO_Central
ComplexPortal		 PMID:10318868 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:3,620,372...3,623,162
Ensembl chr 7:3,620,372...3,623,326 		JBrowse link
G Ndufa4 Ndufa4, mitochondrial complex associated NOT|part_of IMP
IDA
ISO		 (MGI:5442221|PMID:22902835)
(MGI:6383486|PMID:31536960)		 UniProt
RGD		 PMID:22902835 PMID:30361421 PMID:31536960 MGI:5442221 MGI:6383486 RGD:13825197 NCBI chr 6:11,900,371...11,907,449
Ensembl chr 6:11,900,291...11,907,496 		JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 6:24,518,661...24,527,689
Ensembl chr 6:24,518,665...24,528,012 		JBrowse link
G Ndufa6 NADH:ubiquinone oxidoreductase subunit A6 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:82,234,342...82,238,438
Ensembl chr15:82,234,341...82,238,523 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291 		JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:35,926,336...35,939,350
Ensembl chr 2:35,926,338...35,939,418 		JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 part_of
located_in		 IDA
ISO		 (MGI:6383486|PMID:31536960), (PMID:18396137), (PMID:24154540)
(PMID:28844695)		 UniProt
MGI
ComplexPortal		 PMID:18396137 PMID:24154540 PMID:28844695 PMID:31536960 GO_REF:0000119 MGI:4834177 MGI:6383486 NCBI chr 6:126,798,826...126,826,107
Ensembl chr 6:126,798,684...126,826,099 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109 		JBrowse link
G Ndufab1-ps NADH:ubiquinone oxidoreductase subunit AB1b part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:80,156,304...80,158,021
Ensembl chr 7:80,157,535...80,158,002 		JBrowse link
G Ndufb1 NADH:ubiquinone oxidoreductase subunit B1 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr12:101,934,355...101,941,997
Ensembl chr12:101,934,349...101,943,327 		JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:24,941,034...24,943,397
Ensembl chr17:24,941,034...24,943,452 		JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:20,481,565...20,483,858
Ensembl chr  X:20,481,565...20,483,858 		JBrowse link
G Ndufb11b NADH:ubiquinone oxidoreductase subunit B11B part_of ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:81,864,741...81,865,764
Ensembl chr15:81,864,741...81,865,764 		JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 6:39,569,499...39,576,777
Ensembl chr 6:39,569,508...39,580,316 		JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:58,625,556...58,635,123
Ensembl chr 1:58,625,543...58,635,123 		JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:37,467,962...37,474,779
Ensembl chr16:37,467,532...37,474,815 		JBrowse link
G Ndufb4b NADH:ubiquinone oxidoreductase subunit B4B part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:25,010,472...25,010,942
Ensembl chr16:37,467,532...37,474,815
Ensembl chr19:37,467,532...37,474,815 		JBrowse link
G Ndufb4c NADH:ubiquinone oxidoreductase subunit B4C part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:73,681,291...73,681,783
Ensembl chr15:73,681,356...73,681,745 		JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:32,791,206...32,805,708
Ensembl chr 3:32,791,139...32,805,715 		JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 part_of
located_in		 IBA
IDA
ISO		 (PMID:18396137)
(PMID:28844695)		 GO_Central
MGI
ComplexPortal		 PMID:18396137 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421 		JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:84,293,387...84,298,252
Ensembl chr 8:84,293,300...84,298,255 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 part_of
located_in		 IBA
ISO
IDA		 (PMID:24154540)
(PMID:28844695)		 GO_Central
MGI
ComplexPortal		 PMID:24154540 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879 		JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:58,805,650...58,811,365
Ensembl chr15:58,805,605...58,811,337 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:51,312,876...51,323,167
Ensembl chr 3:51,312,098...51,316,409 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:97,049,210...97,057,007
Ensembl chr 7:97,049,210...97,057,009 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 part_of
located_in		 ISO (PMID:28844695) MGI
ComplexPortal		 PMID:28844695 GO_REF:0000119 MGI:4834177 NCBI chr 1:63,182,751...63,215,981
Ensembl chr 1:63,182,755...63,215,992 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 part_of
located_in		 ISO
IBA		 (PMID:28844695) MGI
GO_Central
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr 1:171,062,426...171,078,956
Ensembl chr 1:171,062,422...171,078,957 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 part_of
located_in		 ISO
IDA
IBA		 (MGI:6383486|PMID:31536960), (PMID:18396137), (PMID:24154540)
(PMID:28844695)		 MGI
GO_Central
ComplexPortal		 PMID:18396137 PMID:24154540 PMID:28844695 PMID:31536960 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6383486 NCBI chr 2:90,724,971...90,735,065
Ensembl chr 2:90,724,978...90,735,171 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 part_of
located_in		 IBA
ISO
IDA		 (PMID:10747996), (PMID:18396137), (PMID:24154540)
(PMID:28844695)		 GO_Central
MGI
ComplexPortal		 PMID:10747996 PMID:18396137 PMID:24154540 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794 		JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase core subunit S6 part_of
located_in		 IBA
IDA
ISO		 (PMID:23320803)
(PMID:28844695)		 GO_Central
MGI
ComplexPortal		 PMID:23320803 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:73,467,995...73,476,574
Ensembl chr13:73,467,957...73,476,661 		JBrowse link
G Ndufs6b NADH:ubiquinone oxidoreductase subunit S6B part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:80,811,021...80,811,494
Ensembl chr 7:80,811,145...80,811,492 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:80,084,939...80,092,628
Ensembl chr10:80,084,955...80,092,628 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 part_of
located_in		 IDA
IBA
ISO		 (MGI:6383486|PMID:31536960)
(PMID:28844695)		 UniProt
GO_Central
MGI
ComplexPortal		 PMID:28844695 PMID:31536960 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6383486 NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 part_of
located_in		 IDA
ISO
IBA		 (MGI:6383486|PMID:31536960), (MGI:6730397|PMID:29915388)
(PMID:28844695)		 UniProt
MGI
GO_Central
ComplexPortal		 PMID:28844695 PMID:29915388 PMID:31536960 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6383486 MGI:6730397 NCBI chr19:4,057,499...4,062,755
Ensembl chr19:4,057,384...4,062,806 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 part_of
located_in		 IDA
ISO
IBA		 (MGI:6730397|PMID:29915388)
(PMID:28844695)		 UniProt
MGI
GO_Central
ComplexPortal		 PMID:28844695 PMID:29915388 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6730397 NCBI chr17:66,385,790...66,408,554
Ensembl chr17:66,385,633...66,408,554 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase core subunit V3 part_of
located_in		 IBA
ISO		 (PMID:28844695) GO_Central
MGI
ComplexPortal		 PMID:28844695 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:31,739,089...31,750,300
Ensembl chr17:31,739,089...31,750,305 		JBrowse link
G Wdr93 WD repeat domain 93 part_of IBA GO_Central GO_REF:0000033 NCBI chr 7:79,392,897...79,435,700
Ensembl chr 7:79,392,911...79,435,698 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      respirasome 103
        mitochondrial respirasome 95
          mitochondrial respiratory chain complex I 55
            mitochondrial respiratory chain complex I, membrane segment 0
            mitochondrial respiratory chain complex I, peripheral segment 0
Path 2
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      intracellular anatomical structure 14780
        intracellular organelle 13155
          intracellular membrane-bounded organelle 12011
            mitochondrion 1935
              mitochondrial envelope 817
                mitochondrial membrane 770
                  mitochondrial inner membrane 562
                    inner mitochondrial membrane protein complex 158
                      mitochondrial respiratory chain complex I 55
                        mitochondrial respiratory chain complex I, membrane segment 0
                        mitochondrial respiratory chain complex I, peripheral segment 0
paths to the root