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ONTOLOGY REPORT - ANNOTATIONS

Term:voltage-gated chloride channel activity
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Accession:GO:0005247 term browser browse the term
Definition:Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: voltage-dependent chloride channel activity
 xref: reactome:R-HSA-2744228 "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region"


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voltage-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1, calcium activated chloride channel enables IDA (MGI:5461590|PMID:22634729) UniProt PMID:22634729 MGI:5461590 NCBI chr 7:144,142,286...144,305,762
Ensembl chr 7:144,142,286...144,305,711 		JBrowse link
G Ano6 anoctamin 6 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:95,688,724...95,873,353
Ensembl chr15:95,688,724...95,872,632 		JBrowse link
G Clcn1 chloride channel, voltage-sensitive 1 enables ISO
IBA		 MGI
RGD
GO_Central		 PMID:1659664 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:727583 NCBI chr 6:42,263,552...42,292,693
Ensembl chr 6:42,263,619...42,292,690 		JBrowse link
G Clcn2 chloride channel, voltage-sensitive 2 enables ISO
IMP
IBA		 (PMID:11976342) MGI
RGD
GO_Central		 PMID:1311421 PMID:11976342 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:69809 NCBI chr16:20,521,185...20,536,496
Ensembl chr16:20,521,714...20,536,496 		JBrowse link
G Clcn3 chloride channel, voltage-sensitive 3 enables ISO
IBA		 MGI
RGD
GO_Central		 PMID:10915634 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:628537 NCBI chr 8:61,363,423...61,436,351
Ensembl chr 8:61,363,423...61,436,334 		JBrowse link
G Clcn4 chloride channel, voltage-sensitive 4 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:7,285,308...7,303,837
Ensembl chr 7:7,285,308...7,303,850 		JBrowse link
G Clcn5 chloride channel, voltage-sensitive 5 enables ISO
IBA		 MGI
RGD
GO_Central		 PMID:8626585 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:727659 NCBI chr  X:7,020,049...7,185,597
Ensembl chr  X:7,020,049...7,185,597 		JBrowse link
G Clcn6 chloride channel, voltage-sensitive 6 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:148,088,716...148,123,270
Ensembl chr 4:148,088,716...148,123,278 		JBrowse link
G Clcn7 chloride channel, voltage-sensitive 7 enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr17:25,352,353...25,381,077
Ensembl chr17:25,352,365...25,381,078 		JBrowse link
G Clcnka chloride channel, voltage-sensitive Ka enables IBA GO_Central GO_REF:0000033 NCBI chr 4:141,111,922...141,126,017
Ensembl chr 4:141,111,921...141,126,035 		JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb enables IBA GO_Central GO_REF:0000033 NCBI chr 4:141,131,668...141,143,440
Ensembl chr 4:141,131,664...141,143,325 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        monoatomic ion transmembrane transporter activity 733
          monoatomic ion channel activity 445
            monoatomic anion channel activity 103
              chloride channel activity 89
                voltage-gated chloride channel activity 11
                  organellar voltage-gated chloride channel activity 0
Path 2
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        passive transmembrane transporter activity 513
          channel activity 513
            gated channel activity 323
              voltage-gated channel activity 177
                voltage-gated monoatomic ion channel activity 174
                  voltage-gated monoatomic anion channel activity 16
                    voltage-gated chloride channel activity 11
                      organellar voltage-gated chloride channel activity 0
paths to the root