ONTOLOGY REPORT - ANNOTATIONS
Term: complement activation, lectin pathway
Accession: GO:0001867
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Definition: Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
Comment: Note that proteins such as mannose-binding lectin (MBL) and certain serum ficolins can activate the lectin complement pathway.
Synonyms: exact_synonym: complement cascade, lectin pathway
G
Colec10
collectin sub-family member 10
involved_in
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr15:54,274,170...54,329,755
Ensembl chr15:54,274,170...54,329,754
G
Colec11
collectin sub-family member 11
involved_in
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr12:28,644,171...28,673,458
Ensembl chr12:28,644,172...28,673,376
G
Fcna
ficolin A
involved_in
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:25,514,677...25,525,448
Ensembl chr 2:25,514,678...25,518,042
G
Fcnb
ficolin B
involved_in
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:27,966,491...27,974,921
Ensembl chr 2:27,966,390...27,974,897
G
Krt1
keratin 1
involved_in
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr15:101,753,861...101,759,221
Ensembl chr15:101,753,861...101,759,229
G
Masp1
MBL associated serine protease 1
involved_in
IMP IBA ISO
(MGI:3789229|PMID:18424734)
UniProt GO_Central MGI
PMID:18424734
GO_REF:0000033 GO_REF:0000119 MGI:3789229 MGI:4834177
NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565
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Masp2
MBL associated serine protease 2
involved_in
ISO IBA
MGI GO_Central
GO_REF:0000033 GO_REF:0000119 MGI:4834177
NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956
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Mbl1
mannose-binding lectin (protein A) 1
acts_upstream_of_or_within involved_in
ISO IDA IGI
(PMID:15148336)
RGD MGI
PMID:15148336 PMID:16272342
GO_REF:0000096 MGI:4417868 RGD:1582134
NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558
G
Mbl2
mannose-binding lectin (protein C) 2
involved_in acts_upstream_of_or_within
ISO IDA IGI IMP
(PMID:11549596) (PMID:15148336) (PMID:22691502), (PMID:35102342)
UniProt MGI ComplexPortal
PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342
GO_REF:0000008
NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
G
A2m
alpha-2-macroglobulin
involved_in
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
G
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
involved_in
ISO
MGI
GO_REF:0000119 MGI:4834177
NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788
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