Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Peripheral Nerve Injuries
go back to main search page
Accession:DOID:9001240 term browser browse the term
Definition:Injuries to the PERIPHERAL NERVES.
Synonyms:exact_synonym: Peripheral Nerve Injury
 primary_id: MESH:D059348
 xref: EFO:0009510

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
Peripheral Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25014009 NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127 		JBrowse link
G ANK3 ankyrin 3 ISO mRNA:decreased expression:neuron RGD PMID:10915577 RGD:6767305 NCBI chr 9:70,549,665...71,253,928
Ensembl chr 9:70,893,260...71,254,245 		JBrowse link
G APOA4 apolipoprotein A4 ISO protein:increased expression:sciatic nerve (rat) RGD PMID:2120218 RGD:2311210 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698 		JBrowse link
G APOE apolipoprotein E ISO protein:increased expression:sciatic nerve (rat)
mouse model treated with human peptide		 RGD PMID:2419900 PMID:20406857 RGD:6906874 RGD:6906875 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G BDNF brain derived neurotrophic factor ISO mRNA,protein:increased expression:spinal dorsal horn:
mRNA,protein:increased expression:fourth lumbar dorsal root ganglion:		 RGD PMID:11425916 PMID:23466809 RGD:8657088 RGD:8657102 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336 		JBrowse link
G CAPN2 calpain 2 ISO RGD PMID:25150005 RGD:13792585 NCBI chr25:5,845,873...5,905,464
Ensembl chr25:5,846,298...5,905,402 		JBrowse link
G CBL Cbl proto-oncogene ISO mRNA:increased expression:spinal cord RGD PMID:30021515 RGD:126925240 NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481 		JBrowse link
G CBLB Cbl proto-oncogene B ISO mRNA:increased expression:spinal cord RGD PMID:30021515 RGD:126925240 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO L5 spinal nerve;proein:increased expression:rostral ventrolateral medulla (rat) RGD PMID:22466130 RGD:8549494 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416 		JBrowse link
G CHL1 cell adhesion molecule L1 like ISO mRNA, protein:increased expression:dorsal root ganglia (rat) RGD PMID:21452236 RGD:6483040 NCBI chr22:36,299,841...36,512,292
Ensembl chr22:36,300,474...36,512,417 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO protein:increased expression:spinal nerve RGD PMID:15652389 RGD:150530460 NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822 		JBrowse link
G DAG1 dystroglycan 1 ISO RGD PMID:16254495 RGD:11541065 NCBI chr22:10,864,058...10,934,179
Ensembl chr22:10,865,724...10,934,200 		JBrowse link
G EPHB2 EPH receptor B2 ISO mRNA,protein:increased expression:dorsal root ganglion RGD PMID:32149862 RGD:127285658 NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ameliorates ISO RGD PMID:23437108 RGD:405650403 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G HHIP hedgehog interacting protein ISO RGD PMID:19515211 RGD:11552601 NCBI chr 7:91,216,874...91,311,392
Ensembl chr 7:91,216,955...91,310,387 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO mRNA:increased expression RGD PMID:21940431 RGD:5685664 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO protein:decreased expression: : RGD PMID:21693130 RGD:6480665 NCBI chr 9:84,081,713...84,191,112
Ensembl chr 9:84,083,396...84,190,876 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:23000553 RGD:8655963 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150 		JBrowse link
G IL1B interleukin 1 beta ISO tibial and peroneal nerves RGD PMID:23121415 RGD:7204126 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:21492407 RGD:10402827 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G IL6R interleukin 6 receptor ISO RGD PMID:21492407 RGD:10402827 NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610 		JBrowse link
G IRF5 interferon regulatory factor 5 ISO protein:increased expression:spinal dorsal horn RGD PMID:29927790 RGD:40924654 NCBI chr21:97,536,803...97,549,576
Ensembl chr21:97,537,790...97,549,945 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 ISO protein:decreased expression:tibial nerve, motor neuron, neuronal cell body (rat) RGD PMID:24355600 RGD:126908004 NCBI chr 2:14,510,176...14,623,054
Ensembl chr 2:14,510,464...14,619,023 		JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:17640175 PMID:21376041 RGD:6483044 RGD:6483092 NCBI chr  X:128,285,128...128,309,173
Ensembl chr  X:128,285,130...128,299,570 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:17027671 RGD:2325934 NCBI chr 1:94,216,156...94,224,437
Ensembl chr 1:94,216,173...94,224,264 		JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:17027671 RGD:2325934 NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587 		JBrowse link
G NGF nerve growth factor treatment ISO mRNA,protein:increased expression:sciatic nerve: RGD PMID:11425916 PMID:22669154 PMID:27392124 RGD:10413899 RGD:405100230 RGD:8657088 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833 		JBrowse link
G NGFR nerve growth factor receptor treatment ISO RGD PMID:22302815 PMID:22669154 RGD:10413899 RGD:10413905 NCBI chr16:69,894,000...69,914,209
Ensembl chr16:69,894,139...69,912,189 		JBrowse link
G NOG noggin treatment ISO RGD PMID:17258709 RGD:10428775 NCBI chr16:36,816,783...36,818,693
Ensembl chr16:36,817,476...36,818,174 		JBrowse link
G NTS neurotensin ISO mRNA,protein:increased expression:neuron: RGD PMID:8866516 RGD:9743915 NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713 		JBrowse link
G P2RX4 purinergic receptor P2X 4 sexual_dimorphism ISO in male rat; protein:increased expression:microglia RGD PMID:29927790 RGD:40924654 NCBI chr11:116,585,276...116,609,401
Ensembl chr11:116,585,586...116,609,511 		JBrowse link
G PLAU plasminogen activator, urokinase ISO Cavernous Nerve Injury; mRNA:increased expression:pelvic ganglion (rat) RGD PMID:22300381 RGD:7241556 NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286 		JBrowse link
G PROCR protein C receptor ISO RGD PMID:27771530 RGD:13515125 NCBI chr 2:39,464,322...39,481,498
Ensembl chr 2:39,476,110...39,481,641 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 disease_progression ISO RGD PMID:14576556 RGD:5688234 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression: RGD PMID:14871450 RGD:5688227 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G SERPINF1 serpin family F member 1 ISO mRNA:increased expression:pelvic ganglion (rat) RGD PMID:22300381 RGD:7241556 NCBI chr16:1,408,453...1,424,197 JBrowse link
G SHH sonic hedgehog signaling molecule ISO RGD PMID:22994531 RGD:12879407 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:nucleus accumbens
protein:increased expression:dorsal root ganglion:		 RGD PMID:19543754 PMID:24845379 RGD:10450588 RGD:7394752
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO protein:increased expression:dorsal root ganglion: RGD PMID:18514429 RGD:10043379 NCBI chr 8:67,698,067...67,754,407
Ensembl chr 8:67,698,786...67,751,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15274
    Wounds and Injuries 925
      Nerve Injuries 43
        Peripheral Nerve Injuries 39
Path 2
Term Annotations click to browse term
  disease 15274
    disease of anatomical entity 14894
      nervous system disease 12973
        Nervous System Trauma 569
          Peripheral Nerve Injuries 39
paths to the root