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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:impulse control disorder
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Accession:DOID:10937 term browser browse the term
Definition:A disease of mental health that involves a failure to resist an impulsive act or behaviour that may be harmful to self or others. (DO)
Synonyms:exact_synonym: disruptive, impulse control, and conduct disorders
 primary_id: MESH:D007174
 xref: ICD10CM:F63.9;   ICD9CM:312.30;   MONDO:0001162;   NCI:C34723
For additional species annotation, visit the Alliance of Genome Resources.

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show annotations for term's descendants           Sort by:
impulse control disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17332411 PMID:19940168 PMID:20671181 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17332411 PMID:19940168 PMID:20671181 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18539927 NCBI chrNW_004955555:2,438,864...2,445,846
Ensembl chrNW_004955555:2,438,864...2,445,846 		JBrowse link
G Prl prolactin ISO associated with substance abuse;protein:increased expression:blood plasma (human) RGD PMID:2720017 RGD:401976444 NCBI chrNW_004955483:4,495,257...4,503,377 JBrowse link
Brunner syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maoa amine oxidase [flavin-containing] A ISO ClinVar Annotator: match by term: Brunner syndrome | ClinVar Annotator: match by term: MAOA-related condition OMIM
ClinVar		 PMID:8211186 PMID:9536098 PMID:11700166 PMID:17296899 PMID:17576681 More... NCBI chrNW_004955516:4,494,133...4,576,317
Ensembl chrNW_004955516:4,493,946...4,576,317 		JBrowse link
G Maob monoamine oxidase B ISO ClinVar Annotator: match by term: Brunner syndrome ClinVar PMID:8211186 PMID:17296899 PMID:20340138 PMID:22382802 PMID:28492532 More... NCBI chrNW_004955516:4,328,286...4,473,419
Ensembl chrNW_004955516:4,328,476...4,472,593 		JBrowse link
G Ndp norrin cystine knot growth factor NDP ISO ClinVar Annotator: match by term: Brunner syndrome ClinVar PMID:8211186 PMID:17296899 PMID:20340138 PMID:22382802 PMID:28492532 More... NCBI chrNW_004955516:4,218,703...4,244,774
Ensembl chrNW_004955516:4,218,703...4,244,846 		JBrowse link
intermittent explosive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase sexual_dimorphism ISO associated with schizophrenia; DNA:polymorphism:cd: p.V158M (human) RGD PMID:11204347 RGD:401950497 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412 		JBrowse link
pathological gambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase susceptibility ISO DNA:SNP:cd: p.V158M (rs4680) (human) RGD PMID:24390676 RGD:401940156 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412 		JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10523822 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Drd4 dopamine receptor D4 ISO DNA:duplication:exon:g.2689_2737dup (human) RGD PMID:10402503 RGD:13210523 NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO DNA:SNP: :102T>C (rs6313) RGD PMID:22740152 RGD:401900607 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
trichotillomania term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slitrk1 SLIT and NTRK like family member 1 ISO ClinVar Annotator: match by term: Trichotillomania OMIM
ClinVar		 PMID:20301778 PMID:25741868 NCBI chrNW_004955404:24,436,394...24,439,749
Ensembl chrNW_004955404:24,437,299...24,439,389 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14195
    disease of anatomical entity 13850
      nervous system disease 12114
        central nervous system disease 10884
          brain disease 10218
            disease of mental health 7342
              impulse control disorder 11
                Brunner syndrome 3
                Kluver-Bucy syndrome + 0
                intermittent explosive disorder 1
                kleptomania 0
                pathological gambling 4
                pyromania 0
                trichotillomania 1
paths to the root