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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimipramine
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Accession:CHEBI:9738 term browser browse the term
Definition:A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
Synonyms:exact_synonym: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine
 related_synonym: 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine;   5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;   5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine;   Formula=C20H26N2;   InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3;   InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N;   RP-7162;   SMILES=CC(CN(C)C)CN1c2ccccc2CCc2ccccc12;   Sapilent;   Trimeprimine;   beta-methylimipramine;   trimeproprimine
 xref: Beilstein:1321466;   CAS:739-71-9;   DrugBank:DB00726;   Drug_Central:2758;   HMDB:HMDB0014864;   KEGG:D00394;   LINCS:LSM-1371
 xref_mesh: MESH:D014299
 xref: PMID:22642681;   PMID:25178259;   Patent:CN103893187;   Reaxys:1321466;   Wikipedia:Trimipramine


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trimipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Trimipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        xenobiotic 18738
          trimipramine 1
            trimipramine maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18299
                                    organic heterotricyclic compound 15642
                                      mancude organic heterotricyclic parent 374
                                        5H-dibenzo[b,f]azepine 135
                                          imipramine 135
                                            trimipramine 1
                                              trimipramine maleate 0
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