imipramine - Ontology Report - Rat Genome Database

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Term:	imipramine	go back to main search page
Accession:	CHEBI:47499	browse the term
Definition:	A dibenzoazepine that has formula C19H24N2.
Synonyms:	exact_synonym:	3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
	related_synonym:	10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine; 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE; 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine; Antideprin; C19H24N2; CN(C)CCCN1c2ccccc2CCc2ccccc12; Imipramin; InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3; InChIKey=BCGWQEUPMDMJNV-UHFFFAOYSA-N; Irmin; Melipramine; N-(gamma-dimethylaminopropyl)iminodibenzyl; imipraminum; imizine
	alt_id:	CHEBI:47498; CHEBI:5881
	xref_casrn:	50-49-7
	xref:	Beilstein:256892 "Beilstein Registry Number"; ChEMBL:100605 "ChEMBL COMPOUND"; ChemIDplus:50-49-7 "CAS Registry Number"; DrugBank:DB00458 "DrugBank"; Gmelin:1572523 "Gmelin Registry Number"; KEGG COMPOUND:50-49-7 "CAS Registry Number"; KEGG COMPOUND:C07049 "KEGG COMPOUND"
	xref_mesh:	MESH:D007099
	xref:	NIST Chemistry WebBook:50-49-7 "CAS Registry Number"; PDBeChem:IXX "PDBeChem"; Patent:US2554736 "Patent"; Wikipedia:Imipramine "Wikipedia"

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imipramine
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Aadat	aminoadipate aminotransferase		affects expression	EXP	16	32,845,006	32,885,600	RGD:6480464	CTD
G	Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A		affects expression	EXP	4	21,709,855	21,796,628	RGD:6480464	CTD
G	Adrb1	adrenoceptor beta 1		multiple interactions	EXP	1	263,025,655	263,027,055	RGD:6480464	CTD
G	Adrb1	adrenoceptor beta 1		decreases activity	EXP	1	263,025,655	263,027,055	RGD:6480464	CTD
G	Adrb2	adrenoceptor beta 2, surface		decreases expression	ISO	18	58,174,958	58,177,000	RGD:6480464	CTD
G	Alb	albumin		affects binding	ISO	14	19,126,935	19,142,214	RGD:6480464	CTD
G	Aldh1a1	aldehyde dehydrogenase 1 family, member A1		affects expression	EXP	1	223,731,675	223,773,285	RGD:6480464	CTD
G	Apoa4	apolipoprotein A-IV		affects expression	EXP	8	49,233,142	49,233,431	RGD:6480464	CTD
G	Asah1	N-acylsphingosine amidohydrolase (acid ceramidase) 1		increases expression	ISO	16	54,279,253	54,311,084	RGD:6480464	CTD
G	Asah1	N-acylsphingosine amidohydrolase (acid ceramidase) 1		increases expression	ISO	16	54,279,253	54,311,084	RGD:6480464	CTD
G	Asns	asparagine synthetase (glutamine-hydrolyzing)		increases expression	ISO	4	32,758,866	32,776,220	RGD:6480464	CTD
G	Asns	asparagine synthetase (glutamine-hydrolyzing)		increases expression	ISO	4	32,758,866	32,776,220	RGD:6480464	CTD
G	Bdnf	brain-derived neurotrophic factor		increases expression	ISO				RGD:6480464	CTD
G	Bdnf	brain-derived neurotrophic factor		affects expression	EXP				RGD:6480464	CTD
G	Bdnf	brain-derived neurotrophic factor		increases expression	EXP				RGD:6480464	CTD
G	Bdnf	brain-derived neurotrophic factor		multiple interactions	EXP				RGD:6480464	CTD
G	Bdnf	brain-derived neurotrophic factor		increases expression	EXP				RGD:6480464	CTD
G	Bhmt	betaine-homocysteine S-methyltransferase		affects expression	EXP	2	23,923,651	23,943,320	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		increases activity	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp7	caspase 7		increases activity	ISO	1	262,689,300	262,721,591	RGD:6480464	CTD
G	Casp7	caspase 7		multiple interactions	ISO	1	262,689,300	262,721,591	RGD:6480464	CTD
G	Cat	catalase		affects activity	ISO	3	88,654,077	88,686,212	RGD:6480464	CTD
G	Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)		affects expression	EXP	5	131,012,524	131,017,679	RGD:6480464	CTD
G	Ces2h	carboxylesterase 2H		affects expression	EXP	19	34,910,981	34,925,547	RGD:6480464	CTD
G	Cmtm6	CKLF-like MARVEL transmembrane domain containing 6		affects expression	EXP	8	119,149,810	119,165,515	RGD:6480464	CTD
G	Cpped1	calcineurin-like phosphoesterase domain containing 1		affects expression	EXP	10	3,577,406	3,698,276	RGD:6480464	CTD
G	Creb1	cAMP responsive element binding protein 1		increases expression	EXP	9	63,170,785	63,234,727	RGD:6480464	CTD
G	Creb1	cAMP responsive element binding protein 1		multiple interactions	EXP	9	63,170,785	63,234,727	RGD:6480464	CTD
G	Creb1	cAMP responsive element binding protein 1		increases phosphorylation	ISO	9	63,170,785	63,234,727	RGD:6480464	CTD
G	Crem	cAMP responsive element modulator		affects expression	EXP	17	62,770,633	62,837,670	RGD:6480464	CTD
G	Crh	corticotropin releasing hormone		affects activity	EXP	2	104,764,023	104,765,887	RGD:6480464	CTD
G	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2		affects metabolic processing	ISO	8	61,439,062	61,447,861	RGD:6480464	CTD
G	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2		multiple interactions	ISO	8	61,439,062	61,447,861	RGD:6480464	CTD
G	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2		increases metabolic processing	ISO	8	61,439,062	61,447,861	RGD:6480464	CTD
G	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2		multiple interactions	ISO	8	61,439,062	61,447,861	RGD:6480464	CTD
G	Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1		affects expression	EXP	1	82,006,828	82,020,282	RGD:6480464	CTD
G	Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15		affects expression	EXP	1	81,839,930	81,852,366	RGD:6480464	CTD
G	Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3		affects metabolic processing	ISO	7	120,778,783	120,783,140	RGD:6480464	CTD
G	Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4		affects metabolic processing	ISO	7	120,742,273	120,752,274	RGD:6480464	CTD
G	Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2		multiple interactions	ISO	12	9,517,016	9,541,000	RGD:6480464	CTD
G	Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18		affects expression	EXP	16	18,183,761	18,225,158	RGD:6480464	CTD
G	Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4		affects expression	EXP	7	13,293,080	13,309,416	RGD:6480464	CTD
G	Dcaf8	DDB1 and CUL4 associated factor 8		affects expression	EXP	13	88,029,285	88,186,506	RGD:6480464	CTD
G	Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5		increases expression	ISO	3	170,655,557	170,685,855	RGD:6480464	CTD
G	Eif4b	eukaryotic translation initiation factor 4B		affects expression	EXP	7	140,814,663	140,836,485	RGD:6480464	CTD
G	Ephx1	epoxide hydrolase 1, microsomal (xenobiotic)		affects expression	EXP	13	96,722,973	96,752,940	RGD:6480464	CTD
G	Erp29	endoplasmic reticulum protein 29		affects expression	EXP	12	36,225,110	36,231,363	RGD:6480464	CTD
G	Fabp1	fatty acid binding protein 1, liver		increases expression	ISO	4	104,412,200	104,415,981	RGD:6480464	CTD
G	Fabp1	fatty acid binding protein 1, liver		increases expression	ISO	4	104,412,200	104,415,981	RGD:6480464	CTD
G	Fos	FBJ osteosarcoma oncogene		decreases expression	EXP	6	109,559,135	109,562,001	RGD:6480464	CTD
G	Gap43	growth associated protein 43		decreases expression	EXP	11	59,989,085	60,083,971	RGD:6480464	CTD
G	Gckr	glucokinase (hexokinase 4) regulator		affects expression	EXP				RGD:6480464	CTD
G	Gdpd3	glycerophosphodiester phosphodiesterase domain containing 3		increases expression	ISO	1	185,941,893	185,984,348	RGD:6480464	CTD
G	Gdpd3	glycerophosphodiester phosphodiesterase domain containing 3		increases expression	ISO	1	185,941,893	185,984,348	RGD:6480464	CTD
G	Gls2	glutaminase 2 (liver, mitochondrial)		affects expression	EXP	7	1,484,397	1,495,283	RGD:6480464	CTD
G	Got2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)		affects expression	EXP	19	9,629,687	9,655,336	RGD:6480464	CTD
G	Grb14	growth factor receptor bound protein 14		affects expression	EXP	3	46,832,380	46,952,670	RGD:6480464	CTD
G	Gstp1	glutathione S-transferase pi 1		decreases activity	ISO	1	206,627,398	206,629,866	RGD:6480464	CTD
G	H2afy	H2A histone family, member Y		affects expression	EXP	17	14,457,307	14,520,963	RGD:6480464	CTD
G	Hal	histidine ammonia lyase		affects expression	EXP	7	30,520,913	30,551,145	RGD:6480464	CTD
G	Hdac5	histone deacetylase 5		increases expression	ISO	10	91,266,512	91,277,705	RGD:6480464	CTD
G	Hmbs	hydroxymethylbilane synthase		decreases activity	EXP	8	47,314,235	47,321,604	RGD:6480464	CTD
G	Hmgb2	high mobility group box 2		affects expression	EXP	16	36,131,304	36,133,878	RGD:6480464	CTD
G	Hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)		increases expression	ISO	2	51,737,090	51,754,583	RGD:6480464	CTD
G	Hpn	hepsin		increases expression	ISO	1	86,145,615	86,161,091	RGD:6480464	CTD
G	Hpn	hepsin		increases expression	ISO	1	86,145,615	86,161,091	RGD:6480464	CTD
G	Hspa8	heat shock 70kDa protein 8		increases expression	EXP	8	43,784,035	43,787,760	RGD:6480464	CTD
G	Htr1a	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled		affects expression	EXP	2	36,434,518	36,435,786	RGD:6480464	CTD
G	Htr2a	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled		decreases expression	EXP	15	55,463,743	55,532,293	RGD:6480464	CTD
G	Il33	interleukin 33		affects expression	EXP	1	233,670,801	233,685,798	RGD:6480464	CTD
G	Inhbe	inhibin beta E		increases expression	ISO	7	67,308,713	67,310,138	RGD:6480464	CTD
G	Inhbe	inhibin beta E		increases expression	ISO	7	67,308,713	67,310,138	RGD:6480464	CTD
G	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1		multiple interactions	ISO	13	108,129,617	108,407,815	RGD:6480464	CTD
G	Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2		multiple interactions	ISO	4	6,192,644	6,224,285	RGD:6480464	CTD
G	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2		decreases activity	EXP	18	39,560,962	39,705,037	RGD:6480464	CTD
G	LOC500300	similar to hypothetical protein MGC6835		increases expression	ISO	4	153,000,782	153,002,562	RGD:6480464	CTD
G	LOC500300	similar to hypothetical protein MGC6835		increases expression	ISO	4	153,000,782	153,002,562	RGD:6480464	CTD
G	Lox	lysyl oxidase		affects expression	EXP	18	47,896,674	47,970,829	RGD:6480464	CTD
G	Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)		increases expression	ISO	20	12,507,575	12,534,612	RGD:6480464	CTD
G	Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)		increases expression	ISO	20	12,507,575	12,534,612	RGD:6480464	CTD
G	Manba	mannosidase, beta A, lysosomal		affects expression	EXP	2	232,983,989	233,077,788	RGD:6480464	CTD
G	Mapk1	mitogen activated protein kinase 1		multiple interactions	EXP	11	85,968,732	86,030,387	RGD:6480464	CTD
G	Mapk3	mitogen activated protein kinase 3		multiple interactions	EXP	1	185,935,044	185,941,245	RGD:6480464	CTD
G	Mlx	MLX, MAX dimerization protein		affects expression	EXP	10	90,104,233	90,108,952	RGD:6480464	CTD
G	Mrps18b	mitochondrial ribosomal protein S18B		affects expression	EXP	20	2,985,972	2,992,031	RGD:6480464	CTD
G	Msmo1	methylsterol monooxygenase 1		affects expression	EXP	16	26,698,324	26,716,247	RGD:6480464	CTD
G	Nr0b2	nuclear receptor subfamily 0, group B, member 2		increases expression	ISO	5	151,524,685	151,528,000	RGD:6480464	CTD
G	Nrep	neuronal regeneration related protein		affects expression	EXP	18	25,842,127	25,868,219	RGD:6480464	CTD
G	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2		multiple interactions	ISO	17	11,494,463	11,811,654	RGD:6480464	CTD
G	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2		increases phosphorylation	ISO	17	11,494,463	11,811,654	RGD:6480464	CTD
G	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2		multiple interactions	ISO	17	11,494,463	11,811,654	RGD:6480464	CTD
G	Nupr1	nuclear protein, transcriptional regulator, 1		increases expression	ISO	1	185,770,310	185,772,313	RGD:6480464	CTD
G	Nupr1	nuclear protein, transcriptional regulator, 1		increases expression	ISO	1	185,770,310	185,772,313	RGD:6480464	CTD
G	Oaf	OAF homolog (Drosophila)		affects expression	EXP	8	46,224,861	46,242,832	RGD:6480464	CTD
G	Parp1	poly (ADP-ribose) polymerase 1		increases cleavage	ISO	13	96,309,670	96,341,486	RGD:6480464	CTD
G	Pc	pyruvate carboxylase		affects expression	EXP	1	207,112,853	207,212,737	RGD:6480464	CTD
G	Pecr	peroxisomal trans-2-enoyl-CoA reductase		affects expression	EXP	9	71,414,826	71,443,719	RGD:6480464	CTD
G	Plcg1	phospholipase C, gamma 1		multiple interactions	ISO	3	151,522,949	151,553,998	RGD:6480464	CTD
G	Pomc	proopiomelanocortin		multiple interactions	ISO	6	26,931,969	26,937,789	RGD:6480464	CTD
G	Por	P450 (cytochrome) oxidoreductase		affects expression	EXP	12	22,078,629	22,097,301	RGD:6480464	CTD
G	Rbl2	retinoblastoma-like 2		affects expression	EXP	19	17,045,131	17,092,597	RGD:6480464	CTD
G	RT1-S3	RT1 class Ib, locus S3		affects expression	EXP	20	2,815,943	2,820,644	RGD:6480464	CTD
G	Scd	stearoyl-CoA desaturase (delta-9-desaturase)		increases expression	ISO	1	249,358,105	249,371,164	RGD:6480464	CTD
G	Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N		increases expression	ISO	6	128,461,775	128,469,309	RGD:6480464	CTD
G	Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N		increases expression	ISO	6	128,461,775	128,469,309	RGD:6480464	CTD
G	Serpini1	serpin peptidase inhibitor, clade I (neuroserpin), member 1		increases expression	EXP	2	166,445,765	166,555,032	RGD:6480464	CTD
G	Sh3gl3	SH3-domain GRB2-like 3		affects expression	EXP	1	138,398,336	138,529,056	RGD:6480464	CTD
G	Slc22a3	solute carrier family 22 (extraneuronal monoamine transporter), member 3		multiple interactions	ISO	1	42,690,158	42,781,895	RGD:6480464	CTD
G	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3		decreases expression	ISO	4	159,210,116	159,221,169	RGD:6480464	CTD
G	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3		decreases expression	ISO	4	159,210,116	159,221,169	RGD:6480464	CTD
G	Slc47a1	solute carrier family 47, member 1		decreases activity	ISO	10	47,514,258	47,548,353	RGD:6480464	CTD
G	Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6		affects expression	EXP	4	125,875,817	125,945,795	RGD:6480464	CTD
G	Slco1a4	solute carrier organic anion transporter family, member 1a4		affects expression	EXP				RGD:6480464	CTD
G	Srebf1	sterol regulatory element binding transcription factor 1		multiple interactions	ISO	10	46,461,684	46,483,646	RGD:6480464	CTD
G	Srebf2	sterol regulatory element binding transcription factor 2		multiple interactions	ISO	7	120,522,511	120,580,212	RGD:6480464	CTD
G	St13	suppression of tumorigenicity 13		affects expression	EXP	7	119,694,123	119,728,936	RGD:6480464	CTD
G	Stbd1	starch binding domain 1		affects expression	EXP	14	17,031,752	17,035,157	RGD:6480464	CTD
G	Stmn1	stathmin 1		affects expression	EXP	5	153,226,420	153,232,084	RGD:6480464	CTD
G	Sult2a6	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6		affects expression	EXP	1	74,553,799	74,605,247	RGD:6480464	CTD
G	Tac1	tachykinin, precursor 1		decreases expression	EXP	4	32,649,666	32,657,632	RGD:6480464	CTD
G	Tagln	transgelin		decreases expression	ISO	8	48,902,208	48,907,682	RGD:6480464	CTD
G	Tagln	transgelin		decreases expression	ISO	8	48,902,208	48,907,682	RGD:6480464	CTD
G	Tex261	testis expressed 261		affects expression	EXP	4	117,963,579	117,968,532	RGD:6480464	CTD
G	Timm10b	translocase of inner mitochondrial membrane 10 homolog B		affects expression	EXP	1	163,369,731	163,372,577	RGD:6480464	CTD
G	Tnf	tumor necrosis factor		multiple interactions	ISO	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Uba52	ubiquitin A-52 residue ribosomal protein fusion product 1		affects expression	EXP	16	19,425,401	19,427,557	RGD:6480464	CTD
G	Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1		affects expression	EXP	9	87,091,241	87,098,362	RGD:6480464	CTD
G	Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1		affects expression	EXP	14	22,047,612	22,071,582	RGD:6480464	CTD
G	Ugt2b17	UDP glucuronosyltransferase 2 family, polypeptide B17		affects expression	EXP	14	22,639,182	22,650,931	RGD:6480464	CTD
G	Wipi1	WD repeat domain, phosphoinositide interacting 1		increases expression	ISO	10	98,722,266	98,753,713	RGD:6480464	CTD
G	Wipi1	WD repeat domain, phosphoinositide interacting 1		increases expression	ISO	10	98,722,266	98,753,713	RGD:6480464	CTD
clomipramine
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Aadat	aminoadipate aminotransferase		affects expression	EXP	16	32,845,006	32,885,600	RGD:6480464	CTD
G	Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A		affects expression	EXP	4	21,709,855	21,796,628	RGD:6480464	CTD
G	Aldh1a1	aldehyde dehydrogenase 1 family, member A1		affects expression	EXP	1	223,731,675	223,773,285	RGD:6480464	CTD
G	Ap1s1	adaptor-related protein complex 1, sigma 1 subunit		decreases expression	ISO	12	20,907,855	20,918,301	RGD:6480464	CTD
G	Ap1s1	adaptor-related protein complex 1, sigma 1 subunit		decreases expression	ISO	12	20,907,855	20,918,301	RGD:6480464	CTD
G	Apoa4	apolipoprotein A-IV		affects expression	EXP	8	49,233,142	49,233,431	RGD:6480464	CTD
G	Asns	asparagine synthetase (glutamine-hydrolyzing)		increases expression	ISO	4	32,758,866	32,776,220	RGD:6480464	CTD
G	Bhmt	betaine-homocysteine S-methyltransferase		affects expression	EXP	2	23,923,651	23,943,320	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		increases activity	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp7	caspase 7		multiple interactions	ISO	1	262,689,300	262,721,591	RGD:6480464	CTD
G	Casp7	caspase 7		increases activity	ISO	1	262,689,300	262,721,591	RGD:6480464	CTD
G	Cat	catalase		decreases expression	ISO	3	88,654,077	88,686,212	RGD:6480464	CTD
G	Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)		affects expression	EXP	5	131,012,524	131,017,679	RGD:6480464	CTD
G	Ces2h	carboxylesterase 2H		affects expression	EXP	19	34,910,981	34,925,547	RGD:6480464	CTD
G	Cmtm6	CKLF-like MARVEL transmembrane domain containing 6		affects expression	EXP	8	119,149,810	119,165,515	RGD:6480464	CTD
G	Cpped1	calcineurin-like phosphoesterase domain containing 1		affects expression	EXP	10	3,577,406	3,698,276	RGD:6480464	CTD
G	Crem	cAMP responsive element modulator		affects expression	EXP	17	62,770,633	62,837,670	RGD:6480464	CTD
G	Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1		affects expression	EXP	1	82,006,828	82,020,282	RGD:6480464	CTD
G	Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15		affects expression	EXP	1	81,839,930	81,852,366	RGD:6480464	CTD
G	Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18		affects expression	EXP	16	18,183,761	18,225,158	RGD:6480464	CTD
G	Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4		affects expression	EXP	7	13,293,080	13,309,416	RGD:6480464	CTD
G	Dcaf8	DDB1 and CUL4 associated factor 8		affects expression	EXP	13	88,029,285	88,186,506	RGD:6480464	CTD
G	Drd2	dopamine receptor D2		increases expression	EXP	8	52,641,160	52,707,749	RGD:6480464	CTD
G	Eif4b	eukaryotic translation initiation factor 4B		affects expression	EXP	7	140,814,663	140,836,485	RGD:6480464	CTD
G	Ephx1	epoxide hydrolase 1, microsomal (xenobiotic)		affects expression	EXP	13	96,722,973	96,752,940	RGD:6480464	CTD
G	Erp29	endoplasmic reticulum protein 29		affects expression	EXP	12	36,225,110	36,231,363	RGD:6480464	CTD
G	Fabp1	fatty acid binding protein 1, liver		increases expression	ISO	4	104,412,200	104,415,981	RGD:6480464	CTD
G	Gckr	glucokinase (hexokinase 4) regulator		affects expression	EXP				RGD:6480464	CTD
G	Gdpd3	glycerophosphodiester phosphodiesterase domain containing 3		increases expression	ISO	1	185,941,893	185,984,348	RGD:6480464	CTD
G	Gls2	glutaminase 2 (liver, mitochondrial)		affects expression	EXP	7	1,484,397	1,495,283	RGD:6480464	CTD
G	Got2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)		affects expression	EXP	19	9,629,687	9,655,336	RGD:6480464	CTD
G	Grb14	growth factor receptor bound protein 14		affects expression	EXP	3	46,832,380	46,952,670	RGD:6480464	CTD
G	Gstp1	glutathione S-transferase pi 1		decreases activity	ISO	1	206,627,398	206,629,866	RGD:6480464	CTD
G	H2afy	H2A histone family, member Y		affects expression	EXP	17	14,457,307	14,520,963	RGD:6480464	CTD
G	Hal	histidine ammonia lyase		affects expression	EXP	7	30,520,913	30,551,145	RGD:6480464	CTD
G	Hmgb2	high mobility group box 2		affects expression	EXP	16	36,131,304	36,133,878	RGD:6480464	CTD
G	Hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)		increases expression	ISO	2	51,737,090	51,754,583	RGD:6480464	CTD
G	Hpn	hepsin		increases expression	ISO	1	86,145,615	86,161,091	RGD:6480464	CTD
G	Htr2c	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled		affects binding	ISO	X	31,012,921	31,244,127	RGD:6480464	CTD
G	Htr2c	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled		increases expression	EXP	X	31,012,921	31,244,127	RGD:6480464	CTD
G	Il1a	interleukin 1 alpha		multiple interactions	ISO	3	116,913,612	116,924,114	RGD:6480464	CTD
G	Il33	interleukin 33		affects expression	EXP	1	233,670,801	233,685,798	RGD:6480464	CTD
G	Il6	interleukin 6		multiple interactions	ISO	4	456,799	461,376	RGD:6480464	CTD
G	Inhbe	inhibin beta E		increases expression	ISO	7	67,308,713	67,310,138	RGD:6480464	CTD
G	Inhbe	inhibin beta E		increases expression	ISO	7	67,308,713	67,310,138	RGD:6480464	CTD
G	LOC500300	similar to hypothetical protein MGC6835		increases expression	ISO	4	153,000,782	153,002,562	RGD:6480464	CTD
G	LOC500300	similar to hypothetical protein MGC6835		increases expression	ISO	4	153,000,782	153,002,562	RGD:6480464	CTD
G	Lox	lysyl oxidase		affects expression	EXP	18	47,896,674	47,970,829	RGD:6480464	CTD
G	Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)		increases expression	ISO	20	12,507,575	12,534,612	RGD:6480464	CTD
G	Manba	mannosidase, beta A, lysosomal		affects expression	EXP	2	232,983,989	233,077,788	RGD:6480464	CTD
G	Mlx	MLX, MAX dimerization protein		affects expression	EXP	10	90,104,233	90,108,952	RGD:6480464	CTD
G	Mrps18b	mitochondrial ribosomal protein S18B		affects expression	EXP	20	2,985,972	2,992,031	RGD:6480464	CTD
G	Msmo1	methylsterol monooxygenase 1		affects expression	EXP	16	26,698,324	26,716,247	RGD:6480464	CTD
G	Nr0b2	nuclear receptor subfamily 0, group B, member 2		increases expression	ISO	5	151,524,685	151,528,000	RGD:6480464	CTD
G	Nrep	neuronal regeneration related protein		affects expression	EXP	18	25,842,127	25,868,219	RGD:6480464	CTD
G	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2		increases phosphorylation	ISO	17	11,494,463	11,811,654	RGD:6480464	CTD
G	Nupr1	nuclear protein, transcriptional regulator, 1		increases expression	ISO	1	185,770,310	185,772,313	RGD:6480464	CTD
G	Nupr1	nuclear protein, transcriptional regulator, 1		increases expression	ISO	1	185,770,310	185,772,313	RGD:6480464	CTD
G	Oaf	OAF homolog (Drosophila)		affects expression	EXP	8	46,224,861	46,242,832	RGD:6480464	CTD
G	Parp1	poly (ADP-ribose) polymerase 1		increases cleavage	ISO	13	96,309,670	96,341,486	RGD:6480464	CTD
G	Pc	pyruvate carboxylase		affects expression	EXP	1	207,112,853	207,212,737	RGD:6480464	CTD
G	Pecr	peroxisomal trans-2-enoyl-CoA reductase		affects expression	EXP	9	71,414,826	71,443,719	RGD:6480464	CTD
G	Phyh	phytanoyl-CoA 2-hydroxylase		increases expression	ISO	17	84,418,173	84,435,073	RGD:6480464	CTD
G	Por	P450 (cytochrome) oxidoreductase		affects expression	EXP	12	22,078,629	22,097,301	RGD:6480464	CTD
G	Prl	prolactin		increases expression	ISO	17	44,699,101	44,709,162	RGD:6480464	CTD
G	Prl	prolactin		affects secretion	ISO	17	44,699,101	44,709,162	RGD:6480464	CTD
G	Prl	prolactin		increases secretion	ISO	17	44,699,101	44,709,162	RGD:6480464	CTD
G	Prl	prolactin		multiple interactions	ISO	17	44,699,101	44,709,162	RGD:6480464	CTD
G	Prl	prolactin		increases expression	ISO	17	44,699,101	44,709,162	RGD:6480464	CTD
G	Proc	protein C		increases expression	ISO	18	24,563,368	24,573,715	RGD:6480464	CTD
G	Rbl2	retinoblastoma-like 2		affects expression	EXP	19	17,045,131	17,092,597	RGD:6480464	CTD
G	RT1-S3	RT1 class Ib, locus S3		affects expression	EXP	20	2,815,943	2,820,644	RGD:6480464	CTD
G	Scd	stearoyl-CoA desaturase (delta-9-desaturase)		increases expression	ISO	1	249,358,105	249,371,164	RGD:6480464	CTD
G	Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N		increases expression	ISO	6	128,461,775	128,469,309	RGD:6480464	CTD
G	Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N		increases expression	ISO	6	128,461,775	128,469,309	RGD:6480464	CTD
G	Sh3gl3	SH3-domain GRB2-like 3		affects expression	EXP	1	138,398,336	138,529,056	RGD:6480464	CTD
G	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3		decreases expression	ISO	4	159,210,116	159,221,169	RGD:6480464	CTD
G	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3		decreases expression	ISO	4	159,210,116	159,221,169	RGD:6480464	CTD
G	Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4		multiple interactions	ISO	10	67,134,790	67,155,891	RGD:6480464	CTD
G	Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4		multiple interactions	ISO	10	67,134,790	67,155,891	RGD:6480464	CTD
G	Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6		affects expression	EXP	4	125,875,817	125,945,795	RGD:6480464	CTD
G	Slco1a4	solute carrier organic anion transporter family, member 1a4		affects expression	EXP				RGD:6480464	CTD
G	Srebf1	sterol regulatory element binding transcription factor 1		multiple interactions	ISO	10	46,461,684	46,483,646	RGD:6480464	CTD
G	Srebf2	sterol regulatory element binding transcription factor 2		multiple interactions	ISO	7	120,522,511	120,580,212	RGD:6480464	CTD
G	St13	suppression of tumorigenicity 13		affects expression	EXP	7	119,694,123	119,728,936	RGD:6480464	CTD
G	Stbd1	starch binding domain 1		affects expression	EXP	14	17,031,752	17,035,157	RGD:6480464	CTD
G	Stmn1	stathmin 1		affects expression	EXP	5	153,226,420	153,232,084	RGD:6480464	CTD
G	Sult2a6	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6		affects expression	EXP	1	74,553,799	74,605,247	RGD:6480464	CTD
G	Tac1	tachykinin, precursor 1		decreases expression	EXP	4	32,649,666	32,657,632	RGD:6480464	CTD
G	Tagln	transgelin		decreases expression	ISO	8	48,902,208	48,907,682	RGD:6480464	CTD
G	Tex261	testis expressed 261		affects expression	EXP	4	117,963,579	117,968,532	RGD:6480464	CTD
G	Timm10b	translocase of inner mitochondrial membrane 10 homolog B		affects expression	EXP	1	163,369,731	163,372,577	RGD:6480464	CTD
G	Tnf	tumor necrosis factor		multiple interactions	ISO	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Uba52	ubiquitin A-52 residue ribosomal protein fusion product 1		affects expression	EXP	16	19,425,401	19,427,557	RGD:6480464	CTD
G	Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1		affects expression	EXP	9	87,091,241	87,098,362	RGD:6480464	CTD
G	Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1		affects expression	EXP	14	22,047,612	22,071,582	RGD:6480464	CTD
G	Ugt2b17	UDP glucuronosyltransferase 2 family, polypeptide B17		affects expression	EXP	14	22,639,182	22,650,931	RGD:6480464	CTD
G	Wipi1	WD repeat domain, phosphoinositide interacting 1		increases expression	ISO	10	98,722,266	98,753,713	RGD:6480464	CTD
G	Wipi1	WD repeat domain, phosphoinositide interacting 1		increases expression	ISO	10	98,722,266	98,753,713	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	492507
role	482196
biological role	480389
pharmacological role	122965
neurotransmitter agent	36499
adrenergic agent	16012
adrenergic uptake inhibitor	4537
imipramine	234
clomipramine	101
imipramine hydrochloride	0
trimipramine +	0
Path 2
Term	Annotations
CHEBI ontology	492507
subatomic particle	491470
composite particle	491470
hadron	491470
baryon	491470
nucleon	491470
atomic nucleus	491470
atom	491470
main group element atom	461139
p-block element atom	458635
carbon group element atom	410624
carbon atom	407181
organic molecular entity	407174
organic molecule	298374
organic cyclic compound	298293
organic heterocyclic compound	154322
organic heteropolycyclic compound	95643
organic heterotricyclic compound	37986
dibenzoazepine	578
imipramine	234
clomipramine	101
imipramine hydrochloride	0
trimipramine +	0