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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nevadensin
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Accession:CHEBI:7545 term browser browse the term
Definition:A trimethoxyflavone that is flavone substituted by methoxy groups at positions 6, 8 and 4' and hydroxy groups at positions 5 and 7 respectively.
Synonyms:exact_synonym: 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
 related_synonym: 5,7-hydroxy-4',6,8-trimethoxyflavone;   Formula=C18H16O7;   InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3;   InChIKey=KRFBMPVGAYGGJE-UHFFFAOYSA-N;   Pedunculin;   SMILES=COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(O)c(OC)c2o1
 xref: CAS:10176-66-6;   KEGG:C10111;   KNApSAcK:C00001075;   LIPID_MAPS_instance:LMPK12111442
 xref_mesh: MESH:C023982
 xref: PMID:21775221;   PMID:23747095;   PMID:23894034;   PMID:25218219;   Reaxys:1355696
 cyclic_relationship: is_conjugate_acid_of CHEBI:192756


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nevadensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO nevadensin results in increased activity of CASP3 protein CTD PMID:34635930 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO nevadensin results in increased activity of CASP9 protein CTD PMID:34635930 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [nevadensin results in increased abundance of Hydrogen Peroxide] CTD PMID:34635930 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Top1 DNA topoisomerase I decreases activity ISO nevadensin results in decreased activity of TOP1 protein CTD PMID:34635930 NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO nevadensin results in decreased activity of TOP2A protein CTD PMID:34635930 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            flavone 92
              nevadensin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  oxacycle 17889
                                    benzopyran 11958
                                      1-benzopyran 11710
                                        flavonoid 7193
                                          anthoxanthin 4542
                                            flavones 4542
                                              methoxyflavone 478
                                                trimethoxyflavone 29
                                                  nevadensin 5
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