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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(-)-hinokiresinol
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Accession:CHEBI:435764 term browser browse the term
Definition:A 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene that has 1E,3S configuration. A natural product found in Chamaecyparis obtusa.
Synonyms:exact_synonym: 4-[(1E,3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
 related_synonym: 4-[(1E,3S)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol;   Formula=C17H16O2;   InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2/b6-3+/t14-/m0/s1;   InChIKey=VEAUNWQYYMXIRB-ZRFDWSJLSA-N;   SMILES=C=1C(=CC=C(C1)O)[C@@H](C=C)/C=C/C2=CC=C(C=C2)O
 alt_id: CHEBI:10484;   CHEBI:69979
 xref: Beilstein:1971903;   CAS:17676-24-3;   KEGG:C10628;   KNApSAcK:C00000722
 xref_mesh: MESH:C119821
 xref: PMID:10909263;   PMID:11684179;   PMID:14561517;   PMID:16309307;   PMID:16884819;   PMID:17051467;   PMID:17886842;   PMID:18093914;   PMID:20091263;   PMID:20165801;   Patent:EP2323641;   Patent:US2009312274


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(-)-hinokiresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:30322157 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO hinokiresinol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:30322157 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:30322157 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:30322157 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            (-)-hinokiresinol 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic aromatic compound 19366
                                  phenols 18636
                                    polyphenol 9421
                                      1,3-bis(p-hydroxyphenyl)pentane-1,4-diene 4
                                        (-)-hinokiresinol 4
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