CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Midecamycin
Accession: CHEBI:31845
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Synonyms: related_synonym: Espinomycin A; Formula=C41H67NO15; InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1; InChIKey=DMUAPQTXSSNEDD-QALJCMCCSA-N; Medecamycin A1; Medemycin A1; Midecamycin A1; Platenomycin B1; SMILES=O([C@]1([C@H](O)[C@@H](N(C)C)[C@@H]([C@H](O1)C)O[C@]2(C[C@@](C)(O)[C@H]([C@@H](O2)C)OC(CC)=O)[H])[H])[C@@H]3[C@@H](OC)[C@](OC(CC)=O)(CC(=O)O[C@H](C)CC=CC=C[C@@H]([C@@H](C[C@@H]3CC=O)C)O)[H]; aboren; medemycin; rubimycin; turimycin
xref: CAS:35457-80-8; Drug_Central:1861; KEGG:D01339
xref_mesh: MESH:C026483
G
Abcb11
ATP binding cassette subfamily B member 11
decreases activity
EXP ISO
midecamycin results in decreased activity of ABCB11 protein
CTD
PMID:15618715
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcc2
ATP binding cassette subfamily C member 2
decreases activity
EXP ISO
midecamycin results in decreased activity of ABCC2 protein
CTD
PMID:15618715
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
midecamycin results in increased expression of FOS mRNA; midecamycin results in increased expression of FOS protein
CTD
PMID:32454074
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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