Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,4,6-trichlorophenol
go back to main search page
Accession:CHEBI:28755 term browser browse the term
Definition:A trichlorophenol with phenolic substituents on positions 2, 4 and 6.
Synonyms:related_synonym: 1,3,5-Trichloro-2-hydroxybenzene;   2,4,6-TCP;   Formula=C6H3Cl3O;   InChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H;   InChIKey=LINPIYWFGCPVIE-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)cc(Cl)cc1Cl
 alt_id: CHEBI:19334;   CHEBI:898
 xref: Beilstein:776729;   CAS:88-06-2;   Gmelin:3766;   KEGG:C07098
 xref_mesh: MESH:C024564
 xref: MetaCyc:TRICHLOROPHENOL;   PDBeChem:T6C;   PMID:21863115;   PMID:22748215;   PMID:23995979;   PMID:24078273;   Reaxys:776729;   UM-BBD_compID:c0330;   Wikipedia:2\,4\,6-Trichlorophenol
 cyclic_relationship: is_conjugate_acid_of CHEBI:140426


show annotations for term's descendants           Sort by:
2,4,6-trichlorophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP11A1 mRNA CTD PMID:21296122 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP19A1 mRNA CTD PMID:21296122 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD17B4 mRNA CTD PMID:21296122 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD3B1 mRNA CTD PMID:21296122 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO 2,4,6-trichlorophenol binds to PPARG protein CTD PMID:25314719 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [alitretinoin binds to and results in increased activity of RXRB protein] CTD PMID:27565853 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of STAR mRNA CTD PMID:21296122 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [Triiodothyronine binds to THRB protein] CTD PMID:29409039 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        aetiopathogenetic role 19192
          carcinogenic agent 18517
            2,4,6-trichlorophenol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                carbocyclic compound 18584
                                  benzenoid aromatic compound 17996
                                    benzenes 17858
                                      chlorobenzenes 14840
                                        chlorophenol 1207
                                          trichlorophenols 18
                                            trichlorophenol 18
                                              2,4,6-trichlorophenol 8
paths to the root