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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dibromoacetic acid
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Accession:CHEBI:90124 term browser browse the term
Definition:A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are replaced by bromo groups.
Synonyms:related_synonym: 2,2-Dibromoacetic acid;   2,2-dibromoethanoic acid;   DBAA;   Dibromoethanoic acid;   Formula=C2H2Br2O2;   InChI=1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6);   InChIKey=SIEILFNCEFEENQ-UHFFFAOYSA-N;   SMILES=C(Br)(Br)C(=O)O
 xref: CAS:631-64-1;   Chemspider:11926;   KEGG:C20123;   LIPID_MAPS_instance:LMFA01090076
 xref_mesh: MESH:C088674
 xref: PMID:23348848;   PMID:25556763;   PMID:25955755;   PMID:26052022;   PMID:26188195;   Reaxys:1700457


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dibromoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 increases expression ISO dibromoacetic acid results in increased expression of ATF2 mRNA CTD PMID:29155130 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO dibromoacetic acid results in decreased expression of BCL2 mRNA CTD PMID:18628252 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases expression ISO dibromoacetic acid results in increased expression of CASP3 protein modified form CTD PMID:29155130 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression EXP dibromoacetic acid results in decreased expression of CES3 mRNA CTD PMID:21046364 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP dibromoacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:21046364 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP1B1 mRNA CTD PMID:21046364 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dpt dermatopontin decreases expression EXP dibromoacetic acid results in decreased expression of DPT mRNA CTD PMID:21046364 NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO dibromoacetic acid results in increased expression of ELK1 mRNA CTD PMID:29155130 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP dibromoacetic acid results in decreased expression of FADS1 mRNA CTD PMID:21046364 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein CTD PMID:18628252 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO dibromoacetic acid results in increased expression of FASL protein CTD PMID:18628252 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP dibromoacetic acid results in decreased expression of HAO2 mRNA CTD PMID:21046364 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP dibromoacetic acid results in decreased expression of HBA-A2 mRNA CTD PMID:21046364 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP dibromoacetic acid results in decreased expression of HBB mRNA CTD PMID:21046364 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP dibromoacetic acid results in decreased expression of IGFBP7 mRNA CTD PMID:21046364 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP dibromoacetic acid results in decreased expression of INSL3 mRNA CTD PMID:21046364 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO dibromoacetic acid results in decreased methylation of MYC promoter CTD PMID:16014735 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO dibromoacetic acid results in increased expression of TRAF2 mRNA CTD PMID:18628252 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          apoptosis inducer 13624
            dibromoacetic acid 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        acetic acid 11045
                                          dibromoacetic acid 20
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