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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexane-2,3-dione
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Accession:CHEBI:87583 term browser browse the term
Definition:An alpha-diketone that is hexane substituted by oxo groups at positions 2 and 3 respectively.
Synonyms:related_synonym: Formula=C6H10O2;   InChI=1S/C6H10O2/c1-3-4-6(8)5(2)7/h3-4H2,1-2H3;   InChIKey=MWVFCEVNXHTDNF-UHFFFAOYSA-N;   Methyl propyl diketone;   SMILES=CCCC(=O)C(C)=O
 xref: CAS:3848-24-6;   HMDB:HMDB0031491
 xref_mesh: MESH:C043231
 xref: Reaxys:1699896


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hexane-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of 2,3-hexanedione CTD PMID:10510318 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction
multiple interactions		 ISO AKR1B1 protein results in increased reduction of 2,3-hexanedione
[AKR1B1 protein results in increased reduction of 2,3-hexanedione] which results in increased chemical synthesis of Hexanones		 CTD PMID:10510318 PMID:23295224 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions		 ISO AKR1B10 protein results in increased reduction of 2,3-hexanedione
[AKR1B10 protein results in increased reduction of 2,3-hexanedione] which results in increased chemical synthesis of Hexanones		 CTD PMID:23295224 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Cbr1 carbonyl reductase 1 increases reduction
multiple interactions		 ISO CBR1 protein results in increased reduction of 2,3-hexanedione
8-prenylnaringenin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; [S-Nitrosoglutathione binds to CBR1 protein] inhibits the reaction [CBR1 protein results in increased metabolism of 2,3-hexanedione]; Curcumin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; isoxanthohumol inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; Quercetin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; xanthohumol inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]		 CTD PMID:23295225 PMID:25541467 PMID:30849340 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        biochemical role 19529
          metabolite 19515
            hexane-2,3-dione 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbonyl compound 18898
                                    ketone 17187
                                      diketone 1262
                                        alpha-diketone 218
                                          hexane-2,3-dione 4
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