Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:orientin
go back to main search page
Accession:CHEBI:7781 term browser browse the term
Definition:A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-chromen-4-one
 related_synonym: 8-beta-D-glucosylluteolin;   Formula=C21H20O11;   InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1;   InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N;   Luteolin 8-C-glucoside;   Lutexin;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)c(O)c1
 xref: CAS:28608-75-5;   HMDB:HMDB0030614;   KEGG:C10114;   KNApSAcK:C00001078;   LIPID_MAPS_instance:LMPK12110470
 xref_mesh: MESH:C065886
 xref: PMID:21283956;   PMID:21417394;   PMID:22994444;   PMID:23107458;   PMID:23358325;   Reaxys:69376;   Wikipedia:Orientin


show annotations for term's descendants           Sort by:
orientin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ADIPOQ protein] CTD PMID:32044341 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G INSR insulin receptor increases expression ISO orientin results in increased expression of INSR protein CTD PMID:32044341 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein] CTD PMID:32044341 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G PLA2G4A phospholipase A2 group IVA multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A protein] CTD PMID:32044341 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG protein] CTD PMID:32044341 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A protein] CTD PMID:32044341 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein] CTD PMID:32044341 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      chemical role 24245
        antioxidant 17490
          orientin 7
            3''-oxoorientin(1-) 0
            orientin 2''-O-rhamnoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            organic molecule 25223
                              organic cyclic compound 24277
                                organic heterocyclic compound 22320
                                  oxacycle 20023
                                    benzopyran 12740
                                      1-benzopyran 12476
                                        flavonoid 7601
                                          anthoxanthin 4701
                                            flavones 4701
                                              hydroxyflavone 4680
                                                3'-hydroxyflavonoid 307
                                                  luteolin 243
                                                    orientin 7
                                                      3''-oxoorientin(1-) 0
                                                      orientin 2''-O-rhamnoside 0
paths to the root