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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isopimaric acid
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Accession:CHEBI:6039 term browser browse the term
Definition:A carbotricyclic compound that has formula C20H30O2.
Synonyms:related_synonym: (13S)-pimara-7,15-dien-18-oic acid;   (1R,4aR,4bS,7S,10aR)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid;   4-Epi-isopimaric acid;   Formula=C20H30O2;   InChI=1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,7,15-16H,1,6,8-13H2,2-4H3,(H,21,22)/t15-,16+,18-,19+,20+/m0/s1;   InChIKey=MXYATHGRPJZBNA-KRFUXDQASA-N;   SMILES=[H][C@]12CC[C@@](C)(CC1=CC[C@@]1([H])[C@@](C)(CCC[C@]21C)C(O)=O)C=C
 xref: Beilstein:2293612;   CAS:5835-26-7;   KEGG:C09118;   KNApSAcK:C00003444
 xref_mesh: MESH:C115138
 cyclic_relationship: is_conjugate_acid_of CHEBI:58924


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isopimaric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death increases expression ISO isopimaric acid results in increased expression of BAD protein CTD PMID:36754215 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO isopimaric acid results in increased expression of BAX protein CTD PMID:36754215 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO isopimaric acid results in decreased expression of BCL2L1 protein CTD PMID:36754215 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO isopimaric acid results in decreased expression of CCND1 protein CTD PMID:36754215 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO isopimaric acid results in increased expression of CDH1 protein CTD PMID:36754215 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO isopimaric acid results in decreased expression of CDK2 protein CTD PMID:36754215 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO isopimaric acid results in decreased expression of CDK4 protein CTD PMID:36754215 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO isopimaric acid results in decreased expression of CTNNB1 protein CTD PMID:36754215 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO isopimaric acid results in decreased expression of MKI67 protein CTD PMID:36754215 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO isopimaric acid results in decreased expression of NDUFB8 protein CTD PMID:36754215 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression ISO isopimaric acid results in decreased expression of SDHB protein CTD PMID:36754215 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Vim vimentin decreases expression ISO isopimaric acid results in decreased expression of VIM protein CTD PMID:36754215 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    chemical entity 19846
      atom 19846
        nonmetal atom 19784
          carbon atom 19737
            organic molecular entity 19737
              isoprenoid 14069
                terpenoid 13769
                  diterpenoid 13035
                    isopimaric acid 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    main group molecular entity 19796
                      s-block molecular entity 19629
                        hydrogen molecular entity 19616
                          hydrides 19122
                            organic hydride 18693
                              organic fundamental parent 18693
                                hydrocarbon 18438
                                  terpene 14069
                                    diterpene 13035
                                      isopimarane 12
                                        isopimara-7,15-diene 12
                                          isopimaric acid 12
paths to the root