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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:polymyxin
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Accession:CHEBI:59062 term browser browse the term
Definition:Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria.
Synonyms:related_synonym: polymixin;   polymycin;   polymyxins


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5090
    role 5055
      biological role 5055
        antimicrobial agent 284
          polymyxin 0
            colistimethate 0
            colistimethate A + 0
            colistimethate B + 0
            colistimethate sodium 0
            colistin + 0
            colistin A + 0
            colistin A sodium methanesulfonate + 0
            colistin B + 0
            colistin B sodium methanesulfonate + 0
            polymyxin B1 0
            polymyxin B2 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5090
    subatomic particle 5081
      composite particle 5081
        hadron 5081
          baryon 5081
            nucleon 5081
              atomic nucleus 5081
                atom 5081
                  main group element atom 5051
                    p-block element atom 5048
                      carbon group element atom 4966
                        carbon atom 4965
                          organic molecular entity 4965
                            heteroorganic entity 4805
                              organochalcogen compound 4767
                                organooxygen compound 4728
                                  carbon oxoacid 393
                                    carboxylic acid 388
                                      carboacyl group 214
                                        univalent carboacyl group 214
                                          carbamoyl group 211
                                            carboxamide 211
                                              peptide 55
                                                cyclic peptide 17
                                                  heterodetic cyclic peptide 7
                                                    polymyxin 0
                                                      colistimethate 0
                                                      colistimethate A + 0
                                                      colistimethate B + 0
                                                      colistimethate sodium 0
                                                      colistin + 0
                                                      colistin A + 0
                                                      colistin A sodium methanesulfonate + 0
                                                      colistin B + 0
                                                      colistin B sodium methanesulfonate + 0
                                                      polymyxin B1 0
                                                      polymyxin B2 0
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