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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlordiazepoxide
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Accession:CHEBI:3611 term browser browse the term
Definition:A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.
Synonyms:exact_synonym: 7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide
 related_synonym: 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide;   CDP;   Formula=C16H14ClN3O;   Helogaphen;   InChI=1S/C16H14ClN3O/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15/h2-9H,10H2,1H3,(H,18,19);   InChIKey=ANTSCNMPPGJYLG-UHFFFAOYSA-N;   Libritabs;   Multum;   Risolid;   SMILES=CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=N(=O)C1;   Silibrin;   Tropium;   chlordiazepoxide base;   chlordiazepoxidum;   clopoxide;   methaminodiazepoxide
 xref: Beilstein:550356;   CAS:58-25-3;   DrugBank:DB00475;   Drug_Central:594;   HMDB:HMDB0014618;   KEGG:D00267
 xref_mesh: MESH:D002707
 xref: PMID:17049372;   PMID:19643124;   PMID:9632243;   Patent:MY6500040;   Patent:US2893992;   Patent:US3122474;   Reaxys:550356;   Wikipedia:Chlordiazepoxide


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chlordiazepoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Chlordiazepoxide results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon decreases response to substance EXP GABRE protein results in decreased susceptibility to Chlordiazepoxide CTD PMID:11691872 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693 		JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions EXP Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      application 19661
        pharmaceutical 19502
          adjuvant 4697
            anaesthesia adjuvant 218
              chlordiazepoxide 4
                chlordiazepoxide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    main group molecular entity 19789
                      s-block molecular entity 19626
                        hydrogen molecular entity 19613
                          hydrides 19120
                            inorganic hydride 18118
                              pnictogen hydride 18107
                                nitrogen hydride 18014
                                  azane 17824
                                    ammonia 17823
                                      organic amino compound 17823
                                        secondary amino compound 6838
                                          chlordiazepoxide 4
                                            chlordiazepoxide hydrochloride 0
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