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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lithocholic acid sulfate
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Accession:CHEBI:35421 term browser browse the term
Definition:A steroid sulfate that is lithocholic acid in which the hydroxy hydrogen at position 3 has been replaced by a sulfo group.
Synonyms:exact_synonym: 3alpha-sulfooxy-5beta-cholan-24-oic acid
 related_synonym: (3alpha,5beta)-3-(sulfooxy)cholan-24-oic acid;   Formula=C24H40O6S;   InChI=1S/C24H40O6S/c1-15(4-9-22(25)26)19-7-8-20-18-6-5-16-14-17(30-31(27,28)29)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21H,4-14H2,1-3H3,(H,25,26)(H,27,28,29)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1;   InChIKey=AXDXVEYHEODSPN-HVATVPOCSA-N;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3(CC[C@@]2(C[C@@H](C1)OS(O)(=O)=O)[H])[H])(CC[C@@]4([C@H](C)CCC(O)=O)[H])[H])C)[H])C;   lithocholic acid 3-sulfate;   sulfolithocholic acid
 xref: CAS:34669-57-3
 xref_mesh: MESH:C014202
 cyclic_relationship: is_conjugate_acid_of CHEBI:133940


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lithocholic acid sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions ISO sulfolithocholic acid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein] CTD PMID:16101123 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Gsta4 glutathione S-transferase, alpha 4 multiple interactions ISO sulfolithocholic acid binds to and results in decreased activity of GSTA4 protein CTD PMID:3954743 NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO sulfolithocholic acid binds to and results in decreased activity of GSTM1 protein CTD PMID:3954743 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 multiple interactions ISO sulfolithocholic acid binds to and results in decreased activity of GSTM2 protein CTD PMID:3954743 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22205
    role 22190
      chemical role 21439
        catalyst 8575
          sulfuric acid 8522
            sulfuric acid derivative 8522
              organic sulfate 2537
                steroid sulfate 65
                  lithocholic acid sulfate 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 22205
    subatomic particle 22197
      composite particle 22197
        hadron 22197
          baryon 22197
            nucleon 22169
              atomic nucleus 22197
                atom 22197
                  main group element atom 22131
                    p-block element atom 22131
                      carbon group element atom 21928
                        carbon atom 21854
                          organic molecular entity 21854
                            organic molecule 21671
                              organic cyclic compound 21276
                                organic polycyclic compound 17943
                                  steroid 14887
                                    steroid fundamental parent 14671
                                      cholane 1013
                                        cholanoid 1013
                                          cholanic acids 992
                                            cholanic acid 997
                                              5beta-cholanic acid 997
                                                hydroxy-5beta-cholanic acid 997
                                                  bile acid 997
                                                    lithocholic acid 273
                                                      lithocholic acid sulfate 4
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