ONTOLOGY REPORT - ANNOTATIONS
| Term: | lithocholic acid |
|
| Accession: | CHEBI:16325
|
browse the term
|
| Definition: | A monohydroxy-5beta-cholanic acid that has formula C24H40O3. |
| Synonyms: | exact_synonym: | 3alpha-hydroxy-5beta-cholan-24-oic acid |
| | related_synonym: | (3alpha,5beta)-3-hydroxycholan-24-oic acid; 3alpha-Hydroxy-5beta-cholanic acid; 3alpha-hydroxy-5beta-cholanoic acid; 5beta-cholanic acid-3alpha-ol; C24H40O3; InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1; InChIKey=SMEROWZSTRWXGI-HVATVPOCSA-N; [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@H](O)C2 |
| | alt_id: | CHEBI:1711; CHEBI:20238; CHEBI:20239 |
| | xref_casrn: | 434-13-9 |
| | xref: | ChEMBL:504688 "ChEMBL COMPOUND"; ChemIDplus:3217757 "Beilstein Registry Number"; ChemIDplus:434-13-9 "CAS Registry Number"; KEGG COMPOUND:434-13-9 "CAS Registry Number"; KEGG COMPOUND:C03990 "KEGG COMPOUND"; LIPID MAPS:LMST04010003 "LIPID MAPS instance" |
| | xref_mesh: | MESH:D008095 |
| | xref: | NIST Chemistry WebBook:434-13-9 "CAS Registry Number" |
| | cyclic_relationship: | is_conjugate_acid_of CHEBI:29744 |
|
|
lithocholic acid
|
| G |
Abca1 |
ATP-binding cassette, subfamily A (ABC1), member 1 |
|
decreases expression |
ISO |
5 |
70,493,357 |
70,583,729 |
RGD:6480464 |
CTD |
| G |
Abca1 |
ATP-binding cassette, subfamily A (ABC1), member 1 |
|
multiple interactions |
ISO |
5 |
70,493,357 |
70,583,729 |
RGD:6480464 |
CTD |
| G |
Abca1 |
ATP-binding cassette, subfamily A (ABC1), member 1 |
|
increases expression |
ISO |
5 |
70,493,357 |
70,583,729 |
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
|
increases expression |
ISO |
4 |
21,829,489 |
21,912,239 |
RGD:6480464 |
CTD |
| G |
Abcb4 |
ATP-binding cassette, subfamily B (MDR/TAP), member 4 |
|
increases expression |
ISO |
4 |
21,946,274 |
22,004,328 |
RGD:6480464 |
CTD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
multiple interactions |
ISO |
10 |
452,239 |
575,705 |
RGD:6480464 |
CTD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
increases expression |
ISO |
10 |
452,239 |
575,705 |
RGD:6480464 |
CTD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
increases expression |
ISO |
10 |
452,239 |
575,705 |
RGD:6480464 |
CTD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
multiple interactions |
ISO |
10 |
452,239 |
575,705 |
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
increases expression |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
increases expression |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
multiple interactions |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
increases expression |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
increases expression |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
multiple interactions |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
multiple interactions |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
|
increases expression |
ISO |
10 |
82,986,552 |
83,030,799 |
RGD:6480464 |
CTD |
| G |
Abcc4 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
|
multiple interactions |
ISO |
15 |
103,384,848 |
103,611,238 |
RGD:6480464 |
CTD |
| G |
Abcc4 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
|
increases expression |
ISO |
15 |
103,384,848 |
103,611,238 |
RGD:6480464 |
CTD |
| G |
Abcc4 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
|
multiple interactions |
ISO |
15 |
103,384,848 |
103,611,238 |
RGD:6480464 |
CTD |
| G |
Abcc4 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
|
increases expression |
ISO |
15 |
103,384,848 |
103,611,238 |
RGD:6480464 |
CTD |
| G |
Abcc5 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 5 |
|
increases expression |
ISO |
11 |
82,714,334 |
82,809,354 |
RGD:6480464 |
CTD |
| G |
Abcc5 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 5 |
|
multiple interactions |
ISO |
11 |
82,714,334 |
82,809,354 |
RGD:6480464 |
CTD |
| G |
Abcc5 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 5 |
|
multiple interactions |
ISO |
11 |
82,714,334 |
82,809,354 |
RGD:6480464 |
CTD |
| G |
Abcc5 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 5 |
|
increases expression |
ISO |
11 |
82,714,334 |
82,809,354 |
RGD:6480464 |
CTD |
| G |
Abcc6 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 6 |
|
decreases expression |
ISO |
1 |
96,448,588 |
96,524,655 |
RGD:6480464 |
CTD |
| G |
Abcg2 |
ATP-binding cassette, subfamily G (WHITE), member 2 |
|
increases expression |
ISO |
4 |
87,502,584 |
87,560,017 |
RGD:6480464 |
CTD |
| G |
Abcg2 |
ATP-binding cassette, subfamily G (WHITE), member 2 |
|
multiple interactions |
ISO |
4 |
87,502,584 |
87,560,017 |
RGD:6480464 |
CTD |
| G |
Abcg5 |
ATP-binding cassette, subfamily G (WHITE), member 5 |
|
multiple interactions |
ISO |
6 |
8,027,647 |
8,064,425 |
RGD:6480464 |
CTD |
| G |
Abcg8 |
ATP-binding cassette, subfamily G (WHITE), member 8 |
|
decreases expression |
ISO |
6 |
8,064,631 |
8,083,271 |
RGD:6480464 |
CTD |
| G |
Acaca |
acetyl-CoA carboxylase alpha |
|
multiple interactions |
ISO |
10 |
72,483,772 |
72,677,134 |
RGD:6480464 |
CTD |
| G |
Acaca |
acetyl-CoA carboxylase alpha |
|
decreases expression |
ISO |
10 |
72,483,772 |
72,677,134 |
RGD:6480464 |
CTD |
| G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
|
decreases expression |
ISO |
10 |
56,856,233 |
56,861,380 |
RGD:6480464 |
CTD |
| G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
|
decreases expression |
ISO |
16 |
49,036,892 |
49,081,416 |
RGD:6480464 |
CTD |
| G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
|
multiple interactions |
ISO |
16 |
49,036,892 |
49,081,416 |
RGD:6480464 |
CTD |
| G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
|
decreases activity |
ISO |
17 |
77,084,306 |
77,112,994 |
RGD:6480464 |
CTD |
| G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
|
affects binding |
ISO |
17 |
77,034,737 |
77,081,406 |
RGD:6480464 |
CTD |
| G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
|
decreases activity |
ISO |
17 |
77,034,737 |
77,081,406 |
RGD:6480464 |
CTD |
| G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
|
decreases activity |
ISO |
17 |
77,269,626 |
77,286,521 |
RGD:6480464 |
CTD |
| G |
Anxa1 |
annexin A1 |
|
increases expression |
ISO |
1 |
223,478,436 |
223,494,455 |
RGD:6480464 |
CTD |
| G |
Anxa2 |
annexin A2 |
|
multiple interactions |
ISO |
8 |
73,897,618 |
73,934,041 |
RGD:6480464 |
CTD |
| G |
Anxa2 |
annexin A2 |
|
increases expression |
ISO |
8 |
73,897,618 |
73,934,041 |
RGD:6480464 |
CTD |
| G |
Anxa3 |
annexin A3 |
|
increases expression |
ISO |
14 |
14,245,112 |
14,297,100 |
RGD:6480464 |
CTD |
| G |
Anxa3 |
annexin A3 |
|
multiple interactions |
ISO |
14 |
14,245,112 |
14,297,100 |
RGD:6480464 |
CTD |
| G |
Anxa4 |
annexin A4 |
|
multiple interactions |
ISO |
4 |
120,889,617 |
120,947,662 |
RGD:6480464 |
CTD |
| G |
Anxa4 |
annexin A4 |
|
increases expression |
ISO |
4 |
120,889,617 |
120,947,662 |
RGD:6480464 |
CTD |
| G |
Anxa5 |
annexin A5 |
|
increases expression |
ISO |
2 |
122,949,210 |
122,979,757 |
RGD:6480464 |
CTD |
| G |
Anxa5 |
annexin A5 |
|
multiple interactions |
ISO |
2 |
122,949,210 |
122,979,757 |
RGD:6480464 |
CTD |
| G |
Apoa4 |
apolipoprotein A-IV |
|
increases expression |
ISO |
8 |
49,233,142 |
49,233,431 |
RGD:6480464 |
CTD |
| G |
Apoc1 |
apolipoprotein C-I |
|
decreases expression |
ISO |
1 |
78,996,677 |
78,999,960 |
RGD:6480464 |
CTD |
| G |
Apoc2 |
apolipoprotein C-II |
|
increases expression |
ISO |
1 |
78,979,034 |
78,984,002 |
RGD:6480464 |
CTD |
| G |
Bak1 |
BCL2-antagonist/killer 1 |
|
multiple interactions |
ISO |
20 |
5,255,954 |
5,264,593 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
increases expression |
EXP |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
multiple interactions |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
increases expression |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
increases expression |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
multiple interactions |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Calr |
calreticulin |
|
affects expression |
EXP |
19 |
24,964,775 |
24,969,670 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases cleavage |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Ccnb1 |
cyclin B1 |
|
increases expression |
ISO |
2 |
31,574,600 |
31,581,784 |
RGD:6480464 |
CTD |
| G |
Cd14 |
CD14 molecule |
|
increases expression |
ISO |
18 |
29,374,593 |
29,376,190 |
RGD:6480464 |
CTD |
| G |
Cd14 |
CD14 molecule |
|
multiple interactions |
ISO |
18 |
29,374,593 |
29,376,190 |
RGD:6480464 |
CTD |
| G |
Ces1d |
carboxylesterase 1D |
|
multiple interactions |
ISO |
19 |
14,928,539 |
14,967,082 |
RGD:6480464 |
CTD |
| G |
Ces1d |
carboxylesterase 1D |
|
decreases expression |
ISO |
19 |
14,928,539 |
14,967,082 |
RGD:6480464 |
CTD |
| G |
Ces2a |
carboxylesterase 2A |
|
multiple interactions |
ISO |
19 |
37,686 |
44,736 |
RGD:6480464 |
CTD |
| G |
Chpt1 |
choline phosphotransferase 1 |
|
multiple interactions |
ISO |
7 |
25,171,417 |
25,198,384 |
RGD:6480464 |
CTD |
| G |
Chpt1 |
choline phosphotransferase 1 |
|
decreases expression |
ISO |
7 |
25,171,417 |
25,198,384 |
RGD:6480464 |
CTD |
| G |
Cpt2 |
carnitine palmitoyltransferase 2 |
|
decreases expression |
ISO |
5 |
129,007,685 |
129,025,501 |
RGD:6480464 |
CTD |
| G |
Crot |
carnitine O-octanoyltransferase |
|
multiple interactions |
ISO |
4 |
22,023,913 |
22,067,029 |
RGD:6480464 |
CTD |
| G |
Crot |
carnitine O-octanoyltransferase |
|
decreases expression |
ISO |
4 |
22,023,913 |
22,067,029 |
RGD:6480464 |
CTD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
decreases activity |
ISO |
8 |
61,462,207 |
61,468,237 |
RGD:6480464 |
CTD |
| G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
|
decreases activity |
ISO |
8 |
61,439,062 |
61,447,861 |
RGD:6480464 |
CTD |
| G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
|
decreases activity |
ISO |
6 |
2,548,224 |
2,553,767 |
RGD:6480464 |
CTD |
| G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
|
multiple interactions |
ISO |
3 |
161,542,131 |
161,553,801 |
RGD:6480464 |
CTD |
| G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
|
increases expression |
ISO |
3 |
161,542,131 |
161,553,801 |
RGD:6480464 |
CTD |
| G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
|
decreases expression |
ISO |
9 |
74,039,204 |
74,068,648 |
RGD:6480464 |
CTD |
| G |
Cyp2a3 |
cytochrome P450, family 2, subfamily a, polypeptide 3 |
|
decreases activity |
ISO |
1 |
81,944,896 |
81,953,007 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
increases expression |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
decreases activity |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
|
decreases activity |
ISO |
1 |
243,281,320 |
243,320,945 |
RGD:6480464 |
CTD |
| G |
Cyp2c7 |
cytochrome P450, family 2, subfamily c, polypeptide 7 |
|
decreases activity |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
|
decreases activity |
ISO |
7 |
120,742,273 |
120,752,274 |
RGD:6480464 |
CTD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
decreases activity |
ISO |
1 |
200,918,521 |
200,928,919 |
RGD:6480464 |
CTD |
| G |
Cyp3a18 |
cytochrome P450, family 3, subfamily a, polypeptide 18 |
|
multiple interactions |
ISO |
12 |
9,086,752 |
9,136,606 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
affects metabolic processing |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
increases expression |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
increases expression |
EXP |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
increases expression |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
decreases activity |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a23/3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 |
|
increases expression |
EXP |
12 |
9,567,120 |
9,595,974 |
RGD:6480464 |
CTD |
| G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
|
increases expression |
EXP |
12 |
17,164,384 |
17,204,589 |
RGD:6480464 |
CTD |
| G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
|
multiple interactions |
ISO |
5 |
135,901,653 |
135,915,754 |
RGD:6480464 |
CTD |
| G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
|
decreases expression |
ISO |
5 |
135,901,653 |
135,915,754 |
RGD:6480464 |
CTD |
| G |
Cyp4a3 |
cytochrome P450, family 4, subfamily a, polypeptide 3 |
|
multiple interactions |
ISO |
5 |
135,876,140 |
135,893,753 |
RGD:6480464 |
CTD |
| G |
Cyp4a3 |
cytochrome P450, family 4, subfamily a, polypeptide 3 |
|
decreases expression |
ISO |
5 |
135,876,140 |
135,893,753 |
RGD:6480464 |
CTD |
| G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
|
decreases expression |
ISO |
7 |
13,589,662 |
13,600,856 |
RGD:6480464 |
CTD |
| G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
|
multiple interactions |
ISO |
7 |
13,589,662 |
13,600,856 |
RGD:6480464 |
CTD |
| G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
|
multiple interactions |
ISO |
7 |
13,609,104 |
13,636,290 |
RGD:6480464 |
CTD |
| G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
|
decreases expression |
ISO |
7 |
13,609,104 |
13,636,290 |
RGD:6480464 |
CTD |
| G |
Cyp51 |
cytochrome P450, family 51 |
|
decreases expression |
ISO |
4 |
26,752,677 |
26,771,131 |
RGD:6480464 |
CTD |
| G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
|
decreases expression |
EXP |
5 |
19,707,159 |
19,716,856 |
RGD:6480464 |
CTD |
| G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
|
decreases expression |
ISO |
5 |
19,707,159 |
19,716,856 |
RGD:6480464 |
CTD |
| G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
|
multiple interactions |
ISO |
5 |
19,707,159 |
19,716,856 |
RGD:6480464 |
CTD |
| G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
|
decreases expression |
ISO |
5 |
19,707,159 |
19,716,856 |
RGD:6480464 |
CTD |
| G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
|
decreases expression |
ISO |
5 |
19,707,159 |
19,716,856 |
RGD:6480464 |
CTD |
| G |
Cyp8b1 |
cytochrome P450, family 8, subfamily b, polypeptide 1 |
|
decreases expression |
ISO |
8 |
127,018,908 |
127,020,878 |
RGD:6480464 |
CTD |
| G |
Cyp8b1 |
cytochrome P450, family 8, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
8 |
127,018,908 |
127,020,878 |
RGD:6480464 |
CTD |
| G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
|
increases expression |
ISO |
14 |
6,637,127 |
6,644,100 |
RGD:6480464 |
CTD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
multiple interactions |
ISO |
13 |
96,722,973 |
96,752,940 |
RGD:6480464 |
CTD |
| G |
Fads1 |
fatty acid desaturase 1 |
|
decreases expression |
ISO |
1 |
212,670,792 |
212,685,718 |
RGD:6480464 |
CTD |
| G |
Fads2 |
fatty acid desaturase 2 |
|
decreases expression |
ISO |
1 |
212,512,691 |
212,542,622 |
RGD:6480464 |
CTD |
| G |
Fads6 |
fatty acid desaturase 6 |
|
decreases expression |
ISO |
10 |
105,357,799 |
105,373,626 |
RGD:6480464 |
CTD |
| G |
Fasn |
fatty acid synthase |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Fasn |
fatty acid synthase |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
|
increases expression |
ISO |
8 |
82,724,429 |
82,762,848 |
RGD:6480464 |
CTD |
| G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
|
multiple interactions |
ISO |
8 |
82,724,429 |
82,762,848 |
RGD:6480464 |
CTD |
| G |
Gsta1 |
glutathione S-transferase alpha 1 |
|
multiple interactions |
ISO |
9 |
20,051,501 |
20,068,146 |
RGD:6480464 |
CTD |
| G |
Gsta4 |
glutathione S-transferase alpha 4 |
|
multiple interactions |
ISO |
8 |
83,165,139 |
83,183,055 |
RGD:6480464 |
CTD |
| G |
Gsta4 |
glutathione S-transferase alpha 4 |
|
increases expression |
ISO |
8 |
83,165,139 |
83,183,055 |
RGD:6480464 |
CTD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
multiple interactions |
ISO |
2 |
203,575,444 |
203,580,821 |
RGD:6480464 |
CTD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
increases expression |
ISO |
2 |
203,575,444 |
203,580,821 |
RGD:6480464 |
CTD |
| G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
multiple interactions |
ISO |
2 |
27,127,504 |
27,149,580 |
RGD:6480464 |
CTD |
| G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
|
multiple interactions |
ISO |
2 |
193,128,736 |
193,143,106 |
RGD:6480464 |
CTD |
| G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
|
decreases expression |
ISO |
2 |
193,128,736 |
193,143,106 |
RGD:6480464 |
CTD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
multiple interactions |
ISO |
19 |
13,963,139 |
13,969,960 |
RGD:6480464 |
CTD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
increases expression |
ISO |
19 |
13,963,139 |
13,969,960 |
RGD:6480464 |
CTD |
| G |
Hnf1a |
HNF1 homeobox A |
|
decreases expression |
EXP |
12 |
42,919,574 |
42,945,670 |
RGD:6480464 |
CTD |
| G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
|
decreases expression |
EXP |
3 |
154,459,863 |
154,482,825 |
RGD:6480464 |
CTD |
| G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
|
multiple interactions |
ISO |
3 |
154,459,863 |
154,482,825 |
RGD:6480464 |
CTD |
| G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
|
decreases expression |
ISO |
3 |
154,459,863 |
154,482,825 |
RGD:6480464 |
CTD |
| G |
Idh1 |
isocitrate dehydrogenase 1 (NADP+), soluble |
|
decreases expression |
ISO |
9 |
63,769,401 |
63,790,622 |
RGD:6480464 |
CTD |
| G |
Jun |
jun proto-oncogene |
|
increases expression |
ISO |
5 |
115,358,166 |
115,361,259 |
RGD:6480464 |
CTD |
| G |
Junb |
jun B proto-oncogene |
|
increases expression |
ISO |
19 |
24,831,536 |
24,833,320 |
RGD:6480464 |
CTD |
| G |
Lcat |
lecithin cholesterol acyltransferase |
|
decreases expression |
ISO |
19 |
35,781,507 |
35,784,966 |
RGD:6480464 |
CTD |
| G |
Lcat |
lecithin cholesterol acyltransferase |
|
multiple interactions |
ISO |
19 |
35,781,507 |
35,784,966 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
decreases expression |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Lpl |
lipoprotein lipase |
|
increases expression |
ISO |
16 |
22,533,105 |
22,556,905 |
RGD:6480464 |
CTD |
| G |
Lypla1 |
lysophospholipase I |
|
decreases expression |
ISO |
5 |
14,882,196 |
14,911,284 |
RGD:6480464 |
CTD |
| G |
Lypla1 |
lysophospholipase I |
|
multiple interactions |
ISO |
5 |
14,882,196 |
14,911,284 |
RGD:6480464 |
CTD |
| G |
Mcl1 |
myeloid cell leukemia sequence 1 |
|
affects localization |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Mcl1 |
myeloid cell leukemia sequence 1 |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Mcl1 |
myeloid cell leukemia sequence 1 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Ncoa1 |
nuclear receptor coactivator 1 |
|
multiple interactions |
ISO |
6 |
27,224,396 |
27,473,926 |
RGD:6480464 |
CTD |
| G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
|
multiple interactions |
ISO |
3 |
58,366,693 |
58,394,116 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
increases expression |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
|
increases expression |
EXP |
5 |
151,524,685 |
151,528,000 |
RGD:6480464 |
CTD |
| G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
|
multiple interactions |
ISO |
5 |
151,524,685 |
151,528,000 |
RGD:6480464 |
CTD |
| G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
|
decreases expression |
ISO |
5 |
151,524,685 |
151,528,000 |
RGD:6480464 |
CTD |
| G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
|
increases expression |
ISO |
5 |
151,524,685 |
151,528,000 |
RGD:6480464 |
CTD |
| G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
|
decreases expression |
EXP |
3 |
75,542,211 |
75,550,793 |
RGD:6480464 |
CTD |
| G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
|
decreases expression |
ISO |
3 |
75,542,211 |
75,550,793 |
RGD:6480464 |
CTD |
| G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
|
multiple interactions |
ISO |
7 |
26,189,759 |
26,307,061 |
RGD:6480464 |
CTD |
| G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
|
multiple interactions |
EXP |
7 |
26,189,759 |
26,307,061 |
RGD:6480464 |
CTD |
| G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
|
increases activity |
ISO |
7 |
26,189,759 |
26,307,061 |
RGD:6480464 |
CTD |
| G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
|
decreases expression |
EXP |
7 |
26,189,759 |
26,307,061 |
RGD:6480464 |
CTD |
| G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
|
decreases expression |
ISO |
7 |
26,189,759 |
26,307,061 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
multiple interactions |
ISO |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
decreases response to substance |
ISO |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
multiple interactions |
ISO |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
decreases expression |
EXP |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
decreases response to substance |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases expression |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
multiple interactions |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
multiple interactions |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
decreases response to substance |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
decreases expression |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
multiple interactions |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
|
decreases expression |
EXP |
13 |
49,931,592 |
50,048,756 |
RGD:6480464 |
CTD |
| G |
Orm1 |
orosomucoid 1 |
|
increases expression |
ISO |
5 |
80,325,042 |
80,328,194 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
increases activity |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Pctp |
phosphatidylcholine transfer protein |
|
decreases expression |
ISO |
10 |
78,400,328 |
78,420,774 |
RGD:6480464 |
CTD |
| G |
Pik3r5 |
phosphoinositide-3-kinase, regulatory subunit 5 |
|
increases expression |
ISO |
10 |
55,227,872 |
55,248,301 |
RGD:6480464 |
CTD |
| G |
Plscr1 |
phospholipid scramblase 1 |
|
multiple interactions |
ISO |
8 |
97,206,388 |
97,226,725 |
RGD:6480464 |
CTD |
| G |
Plscr1 |
phospholipid scramblase 1 |
|
increases expression |
ISO |
8 |
97,206,388 |
97,226,725 |
RGD:6480464 |
CTD |
| G |
Ppap2a |
phosphatidic acid phosphatase type 2A |
|
increases expression |
ISO |
2 |
44,183,290 |
44,247,787 |
RGD:6480464 |
CTD |
| G |
Ppap2c |
phosphatidic acid phosphatase type 2c |
|
increases expression |
ISO |
7 |
11,694,272 |
11,702,348 |
RGD:6480464 |
CTD |
| G |
Ppara |
peroxisome proliferator activated receptor alpha |
|
decreases expression |
ISO |
7 |
123,729,774 |
123,807,090 |
RGD:6480464 |
CTD |
| G |
Ppara |
peroxisome proliferator activated receptor alpha |
|
multiple interactions |
ISO |
7 |
123,729,774 |
123,807,090 |
RGD:6480464 |
CTD |
| G |
Psmb4 |
proteasome (prosome, macropain) subunit, beta type 4 |
|
decreases expression |
EXP |
2 |
189,778,476 |
189,781,169 |
RGD:6480464 |
CTD |
| G |
Psmb4 |
proteasome (prosome, macropain) subunit, beta type 4 |
|
affects expression |
EXP |
2 |
189,778,476 |
189,781,169 |
RGD:6480464 |
CTD |
| G |
Rxra |
retinoid X receptor alpha |
|
multiple interactions |
ISO |
3 |
6,605,782 |
6,689,224 |
RGD:6480464 |
CTD |
| G |
Rxrb |
retinoid X receptor beta |
|
affects binding |
ISO |
20 |
4,954,336 |
4,960,880 |
RGD:6480464 |
CTD |
| G |
S100g |
S100 calcium binding protein G |
|
increases expression |
ISO |
X |
52,446,817 |
52,449,342 |
RGD:6480464 |
CTD |
| G |
Scarb1 |
scavenger receptor class B, member 1 |
|
decreases expression |
ISO |
12 |
32,390,183 |
32,457,661 |
RGD:6480464 |
CTD |
| G |
Scarb1 |
scavenger receptor class B, member 1 |
|
increases expression |
ISO |
12 |
32,390,183 |
32,457,661 |
RGD:6480464 |
CTD |
| G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
|
multiple interactions |
ISO |
1 |
249,458,860 |
249,471,460 |
RGD:6480464 |
CTD |
| G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
|
decreases expression |
ISO |
1 |
249,458,860 |
249,471,460 |
RGD:6480464 |
CTD |
| G |
Slc10a1 |
solute carrier family 10 (sodium/bile acid cotransporter family), member 1 |
|
decreases expression |
ISO |
6 |
104,735,839 |
104,749,464 |
RGD:6480464 |
CTD |
| G |
Slc10a1 |
solute carrier family 10 (sodium/bile acid cotransporter family), member 1 |
|
multiple interactions |
ISO |
6 |
104,735,839 |
104,749,464 |
RGD:6480464 |
CTD |
| G |
Slc10a1 |
solute carrier family 10 (sodium/bile acid cotransporter family), member 1 |
|
decreases expression |
ISO |
6 |
104,735,839 |
104,749,464 |
RGD:6480464 |
CTD |
| G |
Slc2a1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
|
increases expression |
ISO |
5 |
139,690,801 |
139,719,021 |
RGD:6480464 |
CTD |
| G |
Slco1a1 |
solute carrier organic anion transporter family, member 1a1 |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Slco1b3 |
solute carrier organic anion transporter family, member 1b3 |
|
decreases expression |
ISO |
4 |
179,045,586 |
179,118,680 |
RGD:6480464 |
CTD |
| G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
|
multiple interactions |
ISO |
10 |
46,461,684 |
46,483,646 |
RGD:6480464 |
CTD |
| G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
|
decreases expression |
ISO |
10 |
46,461,684 |
46,483,646 |
RGD:6480464 |
CTD |
| G |
Stmn1 |
stathmin 1 |
|
increases expression |
ISO |
5 |
153,226,420 |
153,232,084 |
RGD:6480464 |
CTD |
| G |
Tfrc |
transferrin receptor |
|
increases expression |
ISO |
11 |
69,976,258 |
69,998,098 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
increases expression |
ISO |
7 |
23,055,544 |
23,093,815 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
7 |
23,055,544 |
23,093,815 |
RGD:6480464 |
CTD |
| G |
Vdr |
vitamin D (1,25- dihydroxyvitamin D3) receptor |
|
multiple interactions |
ISO |
7 |
136,567,614 |
136,617,280 |
RGD:6480464 |
CTD |
| G |
Vdr |
vitamin D (1,25- dihydroxyvitamin D3) receptor |
|
increases activity |
ISO |
7 |
136,567,614 |
136,617,280 |
RGD:6480464 |
CTD |
| G |
Vdr |
vitamin D (1,25- dihydroxyvitamin D3) receptor |
|
decreases expression |
EXP |
7 |
136,567,614 |
136,617,280 |
RGD:6480464 |
CTD |
| G |
Vdr |
vitamin D (1,25- dihydroxyvitamin D3) receptor |
|
increases expression |
ISO |
7 |
136,567,614 |
136,617,280 |
RGD:6480464 |
CTD |
| G |
Vegfa |
vascular endothelial growth factor A |
|
increases expression |
ISO |
9 |
10,520,730 |
10,536,071 |
RGD:6480464 |
CTD |
| G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
|
increases expression |
ISO |
3 |
25,513,009 |
25,654,964 |
RGD:6480464 |
CTD |
taurolithocholic acid
|
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
affects localization |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Fos |
FBJ osteosarcoma oncogene |
|
increases expression |
ISO |
6 |
109,559,135 |
109,562,001 |
RGD:6480464 |
CTD |
| G |
Fos |
FBJ osteosarcoma oncogene |
|
multiple interactions |
ISO |
6 |
109,559,135 |
109,562,001 |
RGD:6480464 |
CTD |
| G |
Jun |
jun proto-oncogene |
|
increases expression |
ISO |
5 |
115,358,166 |
115,361,259 |
RGD:6480464 |
CTD |
| G |
Jun |
jun proto-oncogene |
|
multiple interactions |
ISO |
5 |
115,358,166 |
115,361,259 |
RGD:6480464 |
CTD |
| G |
Slco1a1 |
solute carrier organic anion transporter family, member 1a1 |
|
affects abundance |
ISO |
|
|
|
RGD:6480464 |
CTD |
taurolithocholic acid sulfate
|
| G |
Cftr |
cystic fibrosis transmembrane conductance regulator |
|
decreases activity |
ISO |
4 |
43,874,852 |
44,041,870 |
RGD:6480464 |
CTD |
Term paths to the root
|