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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Bisphenol A glycidylmethacrylate
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Accession:CHEBI:34580 term browser browse the term
Definition:A diarylmethane that has formula C29H36O8.
Synonyms:related_synonym: 2,2-Bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]propane;   Bis-GMA;   Bisphenol A diglycidyl methacrylate;   Formula=C29H36O8;   InChI=1S/C29H36O8/c1-19(2)27(32)36-17-23(30)15-34-25-11-7-21(8-12-25)29(5,6)22-9-13-26(14-10-22)35-16-24(31)18-37-28(33)20(3)4/h7-14,23-24,30-31H,1,3,15-18H2,2,4-6H3;   InChIKey=AMFGWXWBFGVCKG-UHFFFAOYSA-N;   SMILES=CC(=C)C(=O)OCC(O)COc1ccc(cc1)C(C)(C)c1ccc(OCC(O)COC(=O)C(C)=C)cc1
 xref: CAS:1565-94-2;   KEGG:C14511
 xref_mesh: MESH:D017438



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Bisphenol A glycidylmethacrylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP3 protein
wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP3 protein]
CTD PMID:26756871 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein
wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein]
CTD PMID:26756871 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA] CTD PMID:20673999 PMID:21951919 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnb1 cyclin B1 decreases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA]
CTD PMID:20673999 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdc25c cell division cycle 25C decreases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA]
CTD PMID:20673999 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA]
CTD PMID:20673999 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression
ISO CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA] CTD PMID:21951919 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA
[Loperamide results in decreased activity of CES2 protein] which results in increased susceptibility to Bisphenol A-Glycidyl Methacrylate; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA]
CTD PMID:21951919 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Ces3a carboxylesterase 3a increases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA]
CTD PMID:21951919 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased activity of ESR1 protein
[Bisphenol A-Glycidyl Methacrylate co-treated with 2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate] results in increased activity of ESR1 protein
CTD PMID:11145352 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA]
CTD PMID:20673999 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 mRNA; [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 protein CTD PMID:15264312 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Bisphenol A-Glycidyl Methacrylate co-treated with triethylene glycol dimethacrylate] results in increased expression of TNF mRNA CTD PMID:17140868 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      group 19798
        polyatomic entity 19797
          molecule 19701
            cyclic compound 19516
              organic cyclic compound 19498
                organic aromatic compound 19367
                  diarylmethane 9436
                    Bisphenol A glycidylmethacrylate 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      p-block molecular entity 19789
                        carbon group molecular entity 19737
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic aromatic compound 19367
                                  diarylmethane 9436
                                    Bisphenol A glycidylmethacrylate 14
paths to the root