Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5,6-EET
go back to main search page
Accession:CHEBI:34450 term browser browse the term
Definition:An EET obtained by formal epoxidation of the 5,6-double bond of arachidonic acid.
Synonyms:exact_synonym: 4-{3-[(2Z,5Z,8Z)-tetradeca-2,5,8-trien-1-yl]oxiran-2-yl}butanoic acid
 related_synonym: (8Z,11Z,14Z)-5,6-Epoxyeicosa-8,11,14-trienoic acid;   (8Z,11Z,14Z)-5,6-Epoxyicosa-8,11,14-trienoic acid;   5,6-EpETrE;   5,6-Epoxy-8,11,14-eicosatrienoic acid;   5,6-epoxy-8,11,14-icosatrienoic acid;   5,6-epoxy-8Z,11Z,14Z-eicosatrienoic acid;   5,6-epoxy-8Z,11Z,14Z-icosatrienoic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-;   InChIKey=VBQNSZQZRAGRIX-QNEBEIHSSA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/CC1OC1CCCC(O)=O
 alt_id: CHEBI:63973
 xref: CAS:81246-84-6;   HMDB:HMDB0002190;   KEGG:C14768;   LIPID_MAPS_instance:LMFA03080002
 xref_mesh: MESH:C040776
 xref: Reaxys:4498036
 cyclic_relationship: is_conjugate_acid_of CHEBI:131992


show annotations for term's descendants           Sort by:
5,6-EET term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases chemical synthesis		 ISO Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 5,6-epoxy-8,11,14-eicosatrienoic acid] CTD PMID:12675279 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases abundance ISO EPHX2 gene mutant form results in increased abundance of 5,6-epoxy-8,11,14-eicosatrienoic acid CTD PMID:19896470 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          metabolite 19484
            EET 13
              5,6-EET 2
                5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA 0
                N-[(8Z,11Z,14Z)-5,6-epoxyicosatrienoyl]ethanolamine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        fatty acid 16792
                                          unsaturated fatty acid 1095
                                            polyunsaturated fatty acid 838
                                              fatty acid 20:4 359
                                                icosatetraenoic acid 359
                                                  icosa-5,8,11,14-tetraenoic acid 315
                                                    arachidonic acid 315
                                                      EET 13
                                                        5,6-EET 2
                                                          5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA 0
                                                          N-[(8Z,11Z,14Z)-5,6-epoxyicosatrienoyl]ethanolamine 0
paths to the root