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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:anthraflavic acid
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Accession:CHEBI:34250 term browser browse the term
Definition:A dihydroxyanthraquinone that is anthracene substituted by hydroxy groups at C-3 and C-7 and oxo groups at C-9 and C-10.
Synonyms:exact_synonym: 2,6-dihydroxyanthracene-9,10-dione
 related_synonym: 2,6-Dihydroxyanthraquinone;   2,6-dihydroxy-9,10-anthracenedione;   2,6-dihydroxy-9,10-anthraquinone;   2,6-dihydroxyanthra-9,10-quinone;   Az-F;   Formula=C14H8O4;   InChI=1S/C14H8O4/c15-7-1-3-9-11(5-7)14(18)10-4-2-8(16)6-12(10)13(9)17/h1-6,15-16H;   InChIKey=APAJFZPFBHMFQR-UHFFFAOYSA-N;   SMILES=Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1;   anthraflavin
 xref: Beilstein:2054127;   CAS:84-60-6;   Gmelin:29519;   KEGG:C14267
 xref_mesh: MESH:C034889
 xref: PMID:14500876;   PMID:3128399;   PMID:3209131;   PMID:3282161;   PMID:3492267;   PMID:3689794;   PMID:3802081;   PMID:3918802;   PMID:8304922;   PMID:863051;   Reaxys:2054127


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anthraflavic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 2,6-dihydroxyanthraquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:19269596 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alb albumin affects binding ISO 2,6-dihydroxyanthraquinone binds to ALB protein CTD PMID:16404478 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1A1 mRNA CTD PMID:11502733 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1B1 mRNA CTD PMID:11502733 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:12756209 PMID:14557274 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        antimutagen 92
          anthraflavic acid 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbonyl compound 18869
                                    ketone 17165
                                      cyclic ketone 15685
                                        quinone 8644
                                          acenoquinone 7719
                                            anthraquinone 514
                                              hydroxyanthraquinones 502
                                                dihydroxyanthraquinone 350
                                                  anthraflavic acid 6
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