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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:acetaminophen O-beta-D-glucosiduronic acid
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Accession:CHEBI:32636 term browser browse the term
Definition:A beta-D-glucosiduronic acid that is the O-glucuronide of paracetamol (acetaminophen).
Synonyms:exact_synonym: 4-acetamidophenyl beta-D-glucopyranosiduronic acid
 related_synonym: Acetaminophen glucuronide;   Formula=C14H17NO8;   InChI=1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1;   InChIKey=IPROLSVTVHAQLE-BYNIDDHOSA-N;   Paracetamol glucuronide;   SMILES=CC(=O)Nc1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc1
 xref: CAS:16110-10-4;   HMDB:HMDB0010316
 xref_mesh: MESH:C037386
 xref: PMID:22770225;   Reaxys:46644
 cyclic_relationship: is_conjugate_acid_of CHEBI:132962


show annotations for term's descendants           Sort by:
acetaminophen O-beta-D-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases activity
affects export
multiple interactions		 ISO
EXP		 acetaminophen glucuronide results in increased activity of ABCC3 protein
ABCC3 protein affects the export of acetaminophen glucuronide
Ethinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]		 CTD PMID:16250050 PMID:16554369 PMID:17569508 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ins2 insulin 2 increases abundance ISO INS protein results in increased abundance of acetaminophen glucuronide CTD PMID:26739624 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO OGT gene mutant form inhibits the reaction [Acetaminophen results in increased abundance of acetaminophen glucuronide] CTD PMID:29325178 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        xenobiotic 18739
          paracetamol 12962
            acetaminophen O-beta-D-glucosiduronic acid 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18008
                                        uronic acid 16
                                          hexuronic acid 16
                                            glucuronic acids 15
                                              glucuronic acid 13
                                                D-glucuronic acid 12
                                                  D-glucopyranuronic acid 12
                                                    beta-D-glucuronic acid 4
                                                      acetaminophen O-beta-D-glucosiduronic acid 3
paths to the root