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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:loteprednol etabonate
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Accession:CHEBI:31784 term browser browse the term
Definition:An etabonate ester that has formula C24H31ClO7.
Synonyms:exact_synonym: chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
 related_synonym: Formula=C24H31ClO7;   InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1;   InChIKey=DMKSVUSAATWOCU-HROMYWEYSA-N;   SMILES=[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(OC(=O)OCC)C(=O)OCCl
 xref: Beilstein:5461012;   CAS:82034-46-6;   DrugBank:DB00873;   Drug_Central:1611;   KEGG:D01689
 xref_mesh: MESH:C063378


show annotations for term's descendants           Sort by:
loteprednol etabonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Loteprednol Etabonate binds to and results in decreased activity of AR protein; Loteprednol Etabonate binds to and results in increased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Loteprednol Etabonate binds to and results in increased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        anti-inflammatory agent 16580
          anti-inflammatory drug 14922
            loteprednol etabonate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbonyl compound 18869
                                    ketone 17165
                                      oxo steroid 10530
                                        3-oxo steroid 9919
                                          3-oxo-Delta(1) steroid 5219
                                            3-oxo-Delta(1),Delta(4)-steroid 5219
                                              loteprednol 2
                                                loteprednol etabonate 2
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