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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N(omega)-methyl-L-arginine
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Accession:CHEBI:28229 term browser browse the term
Definition:A L-arginine derivative with a N(omega)-methyl substituent.
Synonyms:exact_synonym: (2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid;   (2S)-2-amino-5-{[imino(methylamino)methyl]amino}pentanoic acid;   N(5)-(N-methylcarbamimidoyl)-L-ornithine;   N(5)-[imino(methylamino)methyl]-L-ornithine
 related_synonym: Formula=C7H16N4O2;   InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1;   InChIKey=NTNWOCRCBQPEKQ-YFKPBYRVSA-N;   L-NMMA;   L-monomethylarginine;   N(5)-(methylamidino)-L-ornithine;   N(5)-(metilamidino)-L-ornitina;   N(G)-monomethyl-L-arginine;   N-monomethyl-L-arginine;   Ngamma-Monomethyl-L-arginine;   SMILES=C(NC(=N)NC)CC[C@@H](C(=O)O)N;   acide (2S)-2-amino-5-(3-methylguanidino)pentanoique;   omega-N-methylarginine;   omega-N-monomethylarginine;   targinina;   targinine;   targininum;   tilarginina;   tilarginine;   tilargininum
 alt_id: CHEBI:21921;   CHEBI:25685;   CHEBI:7547
 xref: Beilstein:2262067;   CAS:17035-90-4;   KEGG:C03884
 xref_mesh: MESH:D019323
 xref: PDBeChem:NMM
 cyclic_relationship: is_conjugate_acid_of CHEBI:67015;   is_tautomer_of CHEBI:60257


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N(omega)-methyl-L-arginine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein] CTD PMID:32526215 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein] CTD PMID:32526215 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        indicator 8765
          biomarker 6574
            L-arginine 91
              L-arginine derivative 76
                N(omega)-methyl-L-arginine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        amino acid 15928
                                          alpha-amino acid 13848
                                            L-alpha-amino acid 12839
                                              glutamine family amino acid 10313
                                                L-arginine 91
                                                  L-arginine derivative 76
                                                    N(omega)-methyl-L-arginine 4
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