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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-Methylspiperone
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Accession:CHEBI:188895 term browser browse the term
Synonyms:exact_synonym: 8-[4-(4-luorophenyl)-4-oxobutyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
 related_synonym: Formula=C24H28FN3O2;   InChI=1S/C24H28FN3O2/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19/h2-4,6-7,9-12H,5,8,13-18H2,1H3;   InChIKey=QHJLPOSPWKZACG-UHFFFAOYSA-N;   SMILES=FC1=CC=C(C(=O)CCCN2CCC3(N(CN(C3=O)C)C4=CC=CC=C4)CC2)C=C1
 xref: CAS:87539-19-3;   Chemspider:106447
 xref_mesh: MESH:C039167


show annotations for term's descendants           Sort by:
N-Methylspiperone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects binding
multiple interactions		 EXP 3-N-methylspiperone binds to DRD2 protein
Aluminum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Cadmium inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Copper inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Gadolinium inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Lanthanum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Zinc Acetate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; zinc chloride inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; Zinc Sulfate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]		 CTD PMID:9109525 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 affects binding
multiple interactions		 EXP 3-N-methylspiperone binds to DRD3 protein
Cadmium inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]; Copper inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]; Gold inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]; Mercury inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]; Silver inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]; Zinc inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]		 CTD PMID:10215675 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 multiple interactions
affects binding		 EXP Cadmium inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]; Copper inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]; Gold inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]; Mercury inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]; Silver inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]; Zinc inhibits the reaction [3-N-methylspiperone binds to DRD4 protein] CTD PMID:10215675 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      group 19765
        inorganic group 19360
          oxo group 18869
            organic oxo compound 18869
              carbonyl compound 18869
                ketone 17165
                  aromatic ketone 12447
                    N-Methylspiperone 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbonyl compound 18869
                                    ketone 17165
                                      aromatic ketone 12447
                                        N-Methylspiperone 3
paths to the root