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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Lucidone
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Accession:CHEBI:183569 term browser browse the term
Synonyms:exact_synonym: 3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one
 related_synonym: Formula=C15H12O4;   InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+;   InChIKey=ANPTXNYQLGJVRE-BQYQJAHWSA-N;   SMILES=O(C=1C(O)=C(C(=O)C1)C(=O)/C=C/C2=CC=CC=C2)C
 xref: Chemspider:9428886;   LIPID_MAPS_instance:LMPK12120439
 xref_mesh: MESH:C529637


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Lucidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO lucidone results in increased expression of HMOX1 protein
[lucidone co-treated with 2,2'-azobis(2-amidinopropane)] results in increased expression of HMOX1 protein; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA]; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]		 CTD PMID:22484158 PMID:23712098 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects response to substance		 ISO [lucidone co-treated with 2,2'-azobis(2-amidinopropane)] affects the localization of and results in increased activity of NFE2L2 protein; [lucidone co-treated with Ethanol] results in increased expression of NFE2L2 mRNA; lucidone affects the localization of and results in increased activity of NFE2L2 protein; lucidone promotes the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of NFE2L2 protein]
NFE2L2 protein affects the susceptibility to lucidone		 CTD PMID:22484158 PMID:23712098 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of NFKBIA protein] CTD PMID:23712098 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of PTGS2 protein] CTD PMID:23712098 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) affects the localization of RELA protein] CTD PMID:23712098 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO lucidone inhibits the reaction [Ethanol results in increased expression of TNF] CTD PMID:22484158 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              olefinic compound 16951
                Lucidone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        alpha,beta-unsaturated monocarboxylic acid 13437
                                          cinnamic acids 2509
                                            cinnamic acid 38
                                              Lucidone 6
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