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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:all-trans-4-oxoretinal
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Accession:CHEBI:139347 term browser browse the term
Definition:A retinoid that is all-trans-retinal carrying an oxo substituent at position 4 on the cyclohexenyl ring.
Synonyms:exact_synonym: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
 related_synonym: 4-Oxoretinaldehyde;   4-ketoretinal;   4-oxoretinal;   Formula=C20H26O2;   InChI=1S/C20H26O2/c1-15(7-6-8-16(2)12-14-21)9-10-18-17(3)19(22)11-13-20(18,4)5/h6-10,12,14H,11,13H2,1-5H3/b8-6+,10-9+,15-7+,16-12+;   InChIKey=PLILDISEFZJECC-RMWYGNQTSA-N;   SMILES=C1(C)(C)C(\\C=C\\C(=C\\C=C\\C(=C\\C(=O)[H])\\C)\\C)=C(C)C(CC1)=O;   all-trans-4-ketoretinal;   all-trans-4-oxo-retinal
 xref: CAS:33532-44-4
 xref_mesh: MESH:C099660
 xref: PMID:10415093;   PMID:12528465;   PMID:15369820;   PMID:1775535;   PMID:17943179;   PMID:8643496;   Reaxys:2508352


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all-trans-4-oxoretinal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction ISO AKR1B1 protein results in increased reduction of 4-oxoretinaldehyde CTD PMID:19014918 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction ISO AKR1B10 protein results in increased reduction of 4-oxoretinaldehyde CTD PMID:19014918 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        inhibitor 18877
          gap junctional intercellular communication inhibitor 35
            all-trans-retinal 33
              all-trans-4-oxoretinal 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      carboacyl group 17677
                                        univalent carboacyl group 17677
                                          formyl group 8999
                                            aldehyde 8999
                                              alpha,beta-unsaturated aldehyde 3032
                                                enal 3032
                                                  retinal 41
                                                    all-trans-retinal 33
                                                      all-trans-4-oxoretinal 2
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