CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: fatty acid oxidation inhibitor
Accession: CHEBI:133190
browse the term
Definition: A compound that inhibits the oxidation of any fatty acid.
Synonyms: related_synonym: fatty acid oxidation inhibitors
xref: Wikipedia:Fatty_acid_oxidation_inhibitors
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Apoa1
apolipoprotein A1
decreases expression
EXP
2-bromopalmitate results in decreased expression of APOA1 mRNA
CTD
PMID:7556148
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Cebpb
CCAAT/enhancer binding protein beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA]
CTD
PMID:30076181
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Fas
Fas cell surface death receptor
decreases expression
ISO
2-bromopalmitate results in decreased expression of FAS mRNA
CTD
PMID:16712844
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases activity
EXP
2-bromopalmitate results in increased activity of GAPDH protein
CTD
PMID:10650946
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA]
CTD
PMID:30076181
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Irf1
interferon regulatory factor 1
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA]
CTD
PMID:30076181
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Lat2
linker for activation of T cells family, member 2
decreases expression
ISO
2-bromopalmitate results in decreased expression of LAT2 protein
CTD
PMID:23001822
NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
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Ldlr
low density lipoprotein receptor
increases expression
ISO
2-bromopalmitate results in increased expression of LDLR mRNA
CTD
PMID:23150725
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lrat
lecithin retinol acyltransferase
increases expression
EXP
2-bromopalmitate results in increased expression of LRAT mRNA
CTD
PMID:12576510
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
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Ly6e
lymphocyte antigen 6 family member E
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA]
CTD
PMID:30076181
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
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Mpo
myeloperoxidase
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA]
CTD
PMID:30076181
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Ppard
peroxisome proliferator-activated receptor delta
increases activity multiple interactions
ISO
2-bromopalmitate results in increased activity of PPARD protein 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD
PMID:15997096 PMID:21543282 PMID:23150725
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression
EXP
2-bromopalmitate results in increased expression of PPARG protein
CTD
PMID:10650946
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Rara
retinoic acid receptor, alpha
multiple interactions
ISO
2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein
CTD
PMID:30076181
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rarb
retinoic acid receptor, beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA]
CTD
PMID:30076181
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rbp1
retinol binding protein 1
increases expression
EXP
2-bromopalmitate results in increased expression of RBP1 mRNA
CTD
PMID:12576510
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rxra
retinoid X receptor alpha
multiple interactions
ISO
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD
PMID:15997096
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Spi1
Spi-1 proto-oncogene
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA]
CTD
PMID:30076181
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Tgm2
transglutaminase 2
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]
CTD
PMID:30076181
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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Ucp2
uncoupling protein 2
increases expression
EXP
2-bromopalmitate results in increased expression of UCP2 mRNA
CTD
PMID:11341955
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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