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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethoxzolamide
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Accession:CHEBI:101096 term browser browse the term
Definition:A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Synonyms:exact_synonym: 6-ethoxy-1,3-benzothiazole-2-sulfonamide
 related_synonym: 6-Ethoxy-benzothiazole-2-sulfonic acid amide;   6-ethoxy-2-benzothiazolesulfonamide;   6-ethoxybenzothiazole-2-sulfonamide;   Formula=C9H10N2O3S2;   InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13);   InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N;   SMILES=CCOc1ccc2nc(sc2c1)S(N)(=O)=O;   ethoxazolamide;   ethoxyzolamide
 xref: CAS:452-35-7;   DrugBank:DB00311;   Drug_Central:1089;   KEGG:D02441;   LINCS:LSM-18787
 xref_mesh: MESH:D005016
 xref: PMID:10411484;   PMID:11087579;   PMID:11123998;   PMID:11906288;   PMID:12039560;   PMID:12617903;   PMID:12617904;   PMID:12643899;   PMID:12747790;   PMID:12747791;   PMID:14611846;   PMID:14640555;   PMID:14684333;   PMID:14971907;   PMID:15081039;   PMID:15139757;   PMID:15149691;   PMID:15454239;   PMID:15456265;   PMID:15501039;   PMID:15546717;   PMID:15603956;   PMID:15664816;   PMID:15686894;   PMID:15686895;   PMID:15686931;   PMID:15771455;   PMID:15837316;   PMID:15837325;   PMID:15905091;   PMID:15908201;   PMID:15908204;   PMID:16033263;   PMID:16039848;   PMID:16039853;   PMID:16165351;   PMID:16168653;   PMID:16302824;   PMID:16459077;   PMID:16539401;   PMID:16809036;   PMID:16942027;   PMID:17064072;   PMID:17125255;   PMID:17157501;   PMID:17228881;   PMID:17251018;   PMID:17276072;   PMID:17343373;   PMID:17475500;   PMID:17482815;   PMID:17540563;   PMID:17588751;   PMID:17646100;   PMID:17681760;   PMID:17826101;   PMID:18042384;   PMID:18242985;   PMID:18307288;   PMID:18359629;   PMID:18374572;   PMID:18513964;   PMID:2585443;   PMID:2810337;   PMID:6737424;   Patent:GB795174;   Patent:US2868800;   Wikipedia:Ethoxzolamide


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ethoxzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pharmaceutical 19468
          drug 19468
            diuretic 4106
              ethoxzolamide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      chalcogen 19513
                        oxygen atom 19488
                          oxygen molecular entity 19488
                            hydroxides 19299
                              oxoacid 18736
                                chalcogen oxoacid 13754
                                  sulfur oxoacid 13542
                                    sulfonic acid 11577
                                      sulfonic acid derivative 11577
                                        sulfonamide 5287
                                          ethoxzolamide 3
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