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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Car3
Name: carbonic anhydrase 3
Acc ID: CHEBI:101096
Term: ethoxzolamide
Definition: A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Chemical ID: MESH:D005016
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Car3multiple interactionsISOCA3 (Homo sapiens)6480464CTDEthoxzolamide binds to and results in decreased activity of CA3 proteinPMID:17826101
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