Med13l (mediator complex subunit 13L) - Rat Genome Database

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Gene: Med13l (mediator complex subunit 13L) Rattus norvegicus
Analyze
Symbol: Med13l
Name: mediator complex subunit 13L
RGD ID: 1305884
Description: Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Human ortholog(s) of this gene implicated in dextro-looped transposition of the great arteries. Orthologous to human MED13L (mediator complex subunit 13L); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360817; mediator complex subunit 13-like; mediator of RNA polymerase II transcription subunit 13-like; Thrap2; thyroid hormone receptor associated protein 2; thyroid hormone receptor-associated 240-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,468,556 - 43,665,819 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1243,468,556 - 43,665,819 (-)EnsemblGRCr8
mRatBN7.21237,807,596 - 38,004,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)EnsemblmRatBN7.2
Rnor_6.01243,421,317 - 43,576,859 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,421,308 - 43,576,804 (-)Ensemblrn6Rnor6.0
Rnor_5.01245,257,715 - 45,412,653 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41239,136,265 - 39,181,221 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1239,469,893 - 39,630,500 (-)NCBICelera
RGSC_v3.11239,012,458 - 39,153,750 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
chlorpyrifos  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP,ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
oxaliplatin  (EXP)
paclitaxel  (ISO)
panobinostat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
theophylline  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mediator complex  (IEA,ISO)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Missense mutations and gene interruption in PROSIT240, a novel TRAP240-like gene, in patients with congenital heart defect (transposition of the great arteries). Muncke N, etal., Circulation. 2003 Dec 9;108(23):2843-50. Epub 2003 Nov 24.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12093747  


Genomics

Comparative Map Data
Med13l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,468,556 - 43,665,819 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1243,468,556 - 43,665,819 (-)EnsemblGRCr8
mRatBN7.21237,807,596 - 38,004,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)EnsemblmRatBN7.2
Rnor_6.01243,421,317 - 43,576,859 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,421,308 - 43,576,804 (-)Ensemblrn6Rnor6.0
Rnor_5.01245,257,715 - 45,412,653 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41239,136,265 - 39,181,221 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1239,469,893 - 39,630,500 (-)NCBICelera
RGSC_v3.11239,012,458 - 39,153,750 (-)NCBI
Cytogenetic Map12q16NCBI
MED13L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812115,958,576 - 116,277,693 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12115,957,905 - 116,277,693 (-)Ensemblhg38GRCh38
GRCh3712116,396,381 - 116,715,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612114,880,764 - 115,199,526 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3412114,859,102 - 115,177,863NCBI
Celera12116,025,985 - 116,344,576 (-)NCBICelera
Cytogenetic Map12q24.21NCBI
HuRef12113,407,355 - 113,687,093 (-)NCBIHuRef
CHM1_112116,364,171 - 116,682,739 (-)NCBICHM1_1
T2T-CHM13v2.012115,939,568 - 116,258,754 (-)NCBIT2T-CHM13v2.0
Med13l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395118,698,363 - 118,903,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5118,698,744 - 118,903,503 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385118,560,330 - 118,765,438 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5118,560,679 - 118,765,438 (+)Ensemblmm10GRCm38
MGSCv375119,010,728 - 119,215,447 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365118,821,773 - 119,024,010 (+)NCBIMGSCv36mm8
Celera5115,689,167 - 115,861,251 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map559.1NCBI
Med13l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545514,679,416 - 14,957,532 (+)Ensembl
ChiLan1.0NW_00495545514,679,416 - 14,960,226 (+)NCBIChiLan1.0ChiLan1.0
MED13L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210124,015,884 - 124,335,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112124,012,262 - 124,331,735 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012113,531,181 - 113,850,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112116,906,557 - 117,187,192 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12116,909,244 - 117,065,649 (-)EnsemblpanPan2panpan1.1
MED13L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12612,768,762 - 13,031,251 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2612,770,588 - 13,030,512 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2612,764,292 - 13,059,638 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02613,028,568 - 13,324,202 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2613,029,858 - 13,324,593 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12612,990,722 - 13,286,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02613,073,281 - 13,365,481 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02613,102,596 - 13,397,898 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Med13l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118153,190,760 - 153,480,666 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365585,998,754 - 6,289,867 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365585,998,760 - 6,288,666 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED13L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1436,063,644 - 36,383,800 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11436,061,834 - 36,384,567 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21438,298,853 - 38,578,678 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MED13L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111111,245,201 - 111,563,485 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11111,243,753 - 111,563,663 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037133,499,321 - 133,817,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Med13l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474716,810,076 - 17,118,088 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474716,810,123 - 17,120,758 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Med13l
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11635,060,825 - 35,265,250 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Med13l
1671 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:77
Count of miRNA genes:70
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000042331
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
RH143248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,808,538 - 37,808,759 (+)MAPPERmRatBN7.2
Rnor_6.01243,422,260 - 43,422,480NCBIRnor6.0
Rnor_5.01245,258,658 - 45,258,878UniSTSRnor5.0
RGSC_v3.41239,137,208 - 39,137,428UniSTSRGSC3.4
Celera1239,470,836 - 39,471,056UniSTS
RH 3.4 Map12692.7UniSTS
Cytogenetic Map12q16UniSTS
BI291178  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,809,800 - 37,809,991 (+)MAPPERmRatBN7.2
Rnor_6.01243,423,522 - 43,423,712NCBIRnor6.0
Rnor_5.01245,259,920 - 45,260,110UniSTSRnor5.0
RGSC_v3.41239,138,470 - 39,138,660UniSTSRGSC3.4
Celera1239,472,098 - 39,472,288UniSTS
RH 3.4 Map10583.6UniSTS
Cytogenetic Map12q16UniSTS
AI717557  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81243,599,629 - 43,600,623 (+)Marker Load Pipeline
mRatBN7.21237,938,680 - 37,939,674 (+)MAPPERmRatBN7.2
Rnor_6.01243,549,226 - 43,550,219NCBIRnor6.0
Rnor_5.01245,385,647 - 45,386,640UniSTSRnor5.0
Celera1239,602,835 - 39,603,828UniSTS
RH 3.4 Map12701.5UniSTS
Cytogenetic Map12q16UniSTS
BE116030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,820,414 - 37,820,580 (+)MAPPERmRatBN7.2
Rnor_6.01243,434,169 - 43,434,334NCBIRnor6.0
Rnor_5.01245,270,567 - 45,270,732UniSTSRnor5.0
RGSC_v3.41239,149,118 - 39,149,283UniSTSRGSC3.4
Celera1239,483,334 - 39,483,499UniSTS
RH 3.4 Map12702.4UniSTS
Cytogenetic Map12q16UniSTS
RH140782  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,809,205 - 37,809,348 (+)MAPPERmRatBN7.2
Rnor_6.01243,422,927 - 43,423,069NCBIRnor6.0
Rnor_5.01245,259,325 - 45,259,467UniSTSRnor5.0
RGSC_v3.41239,137,875 - 39,138,017UniSTSRGSC3.4
Celera1239,471,503 - 39,471,645UniSTS
RH 3.4 Map12703.4UniSTS
Cytogenetic Map12q16UniSTS
BE119619  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,859,388 - 37,859,544 (+)MAPPERmRatBN7.2
Rnor_6.01243,473,084 - 43,473,239NCBIRnor6.0
Rnor_5.01245,309,482 - 45,309,637UniSTSRnor5.0
Celera1239,522,102 - 39,522,257UniSTS
RH 3.4 Map12695.9UniSTS
Cytogenetic Map12q16UniSTS
AI717557  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,939,652 - 37,939,825 (+)MAPPERmRatBN7.2
Rnor_6.01243,550,198 - 43,550,370NCBIRnor6.0
Rnor_5.01245,386,619 - 45,386,791UniSTSRnor5.0
Celera1239,603,807 - 39,603,979UniSTS
RH 3.4 Map12701.5UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU566026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042331   ⟹   ENSRNOP00000046404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1243,468,556 - 43,665,819 (-)Ensembl
mRatBN7.2 Ensembl1237,808,285 - 37,966,245 (-)Ensembl
Rnor_6.0 Ensembl1243,423,905 - 43,576,754 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078445   ⟹   ENSRNOP00000073531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1243,468,556 - 43,553,102 (-)Ensembl
mRatBN7.2 Ensembl1237,808,285 - 37,892,151 (-)Ensembl
Rnor_6.0 Ensembl1243,421,308 - 43,503,456 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081780   ⟹   ENSRNOP00000070275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1243,468,556 - 43,627,272 (-)Ensembl
mRatBN7.2 Ensembl1237,808,285 - 37,966,328 (-)Ensembl
Rnor_6.0 Ensembl1243,423,905 - 43,576,804 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120071   ⟹   ENSRNOP00000092543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)Ensembl
RefSeq Acc Id: NM_001419791   ⟹   NP_001406720
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,819 (-)NCBI
mRatBN7.21237,807,596 - 38,004,886 (-)NCBI
RefSeq Acc Id: XM_039090172   ⟹   XP_038946100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,425 (-)NCBI
mRatBN7.21237,807,596 - 38,004,485 (-)NCBI
RefSeq Acc Id: XM_039090173   ⟹   XP_038946101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,425 (-)NCBI
mRatBN7.21237,807,596 - 38,004,485 (-)NCBI
RefSeq Acc Id: XM_039090175   ⟹   XP_038946103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,262 (-)NCBI
mRatBN7.21237,807,596 - 38,004,320 (-)NCBI
RefSeq Acc Id: XM_063271538   ⟹   XP_063127608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,262 (-)NCBI
Ensembl Acc Id: ENSRNOP00000073531   ⟸   ENSRNOT00000078445
Ensembl Acc Id: ENSRNOP00000070275   ⟸   ENSRNOT00000081780
Ensembl Acc Id: ENSRNOP00000046404   ⟸   ENSRNOT00000042331
RefSeq Acc Id: XP_038946101   ⟸   XM_039090173
- Peptide Label: isoform X2
- UniProtKB: D4P4K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946100   ⟸   XM_039090172
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AID1 (UniProtKB/TrEMBL),   D4P4K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946103   ⟸   XM_039090175
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K5R7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092543   ⟸   ENSRNOT00000120071
RefSeq Acc Id: NP_001406720   ⟸   NM_001419791
- UniProtKB: D4P4K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127608   ⟸   XM_063271538
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K5R7 (UniProtKB/TrEMBL)
Protein Domains
Mediator complex subunit Med13 C-terminal   Mediator complex subunit Med13 N-terminal   MID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXH7-F1-model_v2 AlphaFold A0A0G2JXH7 1-2189 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305884 AgrOrtholog
BioCyc Gene G2FUF-19108 BioCyc
Ensembl Genes ENSRNOG00000001120 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042331 ENTREZGENE
  ENSRNOT00000042331.6 UniProtKB/TrEMBL
  ENSRNOT00000078445 ENTREZGENE
  ENSRNOT00000078445.3 UniProtKB/TrEMBL
  ENSRNOT00000081780.3 UniProtKB/TrEMBL
InterPro Mediator_complx_sub13 UniProtKB/TrEMBL
  Mediator_Med13 UniProtKB/TrEMBL
  Mediator_Med13_N UniProtKB/TrEMBL
  MID_MedPIWI UniProtKB/TrEMBL
NCBI Gene 360817 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 UniProtKB/TrEMBL
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE UniProtKB/TrEMBL
Pfam Med13_C UniProtKB/TrEMBL
  Med13_N UniProtKB/TrEMBL
  MID_MedPIWI UniProtKB/TrEMBL
PhenoGen Med13l PhenoGen
RatGTEx ENSRNOG00000001120 RatGTEx
UniProt A0A0G2JXH7_RAT UniProtKB/TrEMBL
  A0A0G2K5R7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AID1 ENTREZGENE
  D4P4K6 ENTREZGENE, UniProtKB/TrEMBL
  F1LZT8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-08-13 Med13l  mediator complex subunit 13L  Med13l  mediator complex subunit 13-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Med13l  mediator complex subunit 13-like  Thrap2_predicted  thyroid hormone receptor associated protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Thrap2_predicted  thyroid hormone receptor associated protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED