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Strain Registration

Strain: HCR/Mco

Symbol: HCR/Mco
Strain: HCR
Substrain: Mco
Full Name: High-capacity runners
RGD ID: 2314397
Citation ID: RRID:RGD_2314397
Ontology ID: RS:0001996
Also Known As: High endurance running capacity
Type: inbred
Available Source: Not Available
Origination: Medical College of Ohio, Toledo, Ohio, USA
Description: Artificially selected for intrinsic aerobic running capacity from the heterogenous stock (N:HS); these were selected for high capacity based on distance run to exhaustion on a motorized treadmill.
Last Known Status: Unknown





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Cardiac function in rats selectively bred for low- and high-capacity running. Hussain SO, etal., Am J Physiol Regul Integr Comp Physiol. 2001 Dec;281(6):R1787-91.
2. Artificial selection for intrinsic aerobic endurance running capacity in rats. Koch LG and Britton SL, Physiol Genomics. 2001 Feb 7;5(1):45-52.
3. Genetic analysis of a rat model of aerobic capacity and metabolic fitness. Ren YY, etal., PLoS One. 2013 Oct 11;8(10):e77588. doi: 10.1371/journal.pone.0077588. eCollection 2013.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_reproduction 13 highest capacity males and females were selected and paired for mating; the resultant offsprings were weaned 28 days after birth; at 10 weeks of age these were introduced to the treadmill and tested for capacity. 2314394