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Strain Registration

Strain: SD-Tg(CAG-HRAS*G12V)250Htsu

Symbol: SD-Tg(CAG-HRAS*G12V)250Htsu
Strain: SD-Tg(CAG-HRAS*G12V)250
Substrain: Htsu
RGD ID: 2314382
Citation ID: RRID:RGD_2314382
Ontology ID: RS:0002121
Alleles: HRAS
Also Known As: SD-Tg(CALNL-HrasGRV)250;Hras250;NBRP Rat No: 0568
Type: transgenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This transgenic strain was established by CLEA Japan, Inc. The construct is as follows: CAG promoter, loxP sequence, neomycin resistance gene, loxP sequence and Ha-ras*G12V (HrasV12). It was injected into Jcl:SD embryos, the transgene is regulated by the Cre/loxP system. Human Ha-ras*G12V oncogene is driven by CAG promoter
Coat Color: Albino
Last Known Status: Cryopreserved Sperm
Research Usage Cancer






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas. Ueda S, etal., Carcinogenesis. 2006 Dec;27(12):2497-510. Epub 2006 Jun 13.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-29 SD-Tg(CAG-HRAS*G12V)250Htsu    SD-Tg(CAG-HRAS*G12V)250Htsu    Name updated 68913 APPROVED
2012-05-29 SD-Tg(CAG-HRAS*G12V)250Htsu    SD-Tg(CAG-HRAS*G12V)250Htsu    Name updated 68913 APPROVED