Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Strain Registration

Strain: MPR/Iar

Symbol: MPR/Iar
Strain: MPR
Substrain: Iar
RGD ID: 2306064
Citation ID: RRID:RGD_2306064
Ontology ID: RS:0002072
Alleles: ArsbMPR;   Arsb
Variant(s): ArsbMPR-var1
Also Known As: MPR-Arsbabd/Iar; MPR; MPR-Arsbabd/Iar; NBRP Rat No: 0474
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Developed by the DEPOSITOR
Coat Color: Albino
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2024-09-24)
Research Usage Metabolism; Osteosis





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Anti-TNF-alpha therapy enhances the effects of enzyme replacement therapy in rats with mucopolysaccharidosis type VI. Eliyahu E, etal., PLoS One. 2011;6(8):e22447. doi: 10.1371/journal.pone.0022447. Epub 2011 Aug 22.
2. Mucopolysaccharidosis type VI in rats: isolation of cDNAs encoding arylsulfatase B, chromosomal localization of the gene, and identification of the mutation. Kunieda T, etal., Genomics 1995 Oct 10;29(3):582-7.
3. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. Arylsulfatase B-deficient mucopolysaccharidosis in rats. Yoshida M, etal., J Clin Invest 1993 Mar;91(3):1099-104.

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
ArsbMPR-var1 chr2 25020848 25020849 - C insertion mRatBN7.2

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_reproduction Homozygous Arsb rats are difficult to breed and are therefore maintained by crossing heterozygous individuals (segregating inbred strain). 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-18 MPR/Iar    MPR/Iar    Name updated 68913 APPROVED
2012-05-18 MPR/Iar    MPR/Iar    Name updated 68913 APPROVED