Gene: Arsb (arylsulfatase B) Rattus norvegicus
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Symbol: Arsb
Name: arylsulfatase B
Description: ENCODES a protein that exhibits sulfuric ester hydrolase activity; arylsulfatase activity (ortholog); N-acetylgalactosamine-4-sulfatase activity (ortholog); INVOLVED IN autophagy; central nervous system development; positive regulation of neuron projection development; PARTICIPATES IN glycosaminoglycan degradation pathway; ASSOCIATED WITH Mucopolysaccharidosis VI; mucopolysaccharidosis VI; FOUND IN cell surface; Golgi apparatus; lysosome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Arylsulfatase B (MPS VI); ASB; G4S; N-acetylgalactosamine-4-sulfatase
Orthologs:
Homo sapiens (human) : ARSB (arylsulfatase B)  HGNC  AGR
Mus musculus (house mouse) : Arsb (arylsulfatase B)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Arsb (arylsulfatase B)
Pan paniscus (bonobo/pygmy chimpanzee) : ARSB (arylsulfatase B)
Canis lupus familiaris (dog) : ARSB (arylsulfatase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arsb (arylsulfatase B)
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Allele / Splice: ArsbMPR  
Genetic Models: WIAR.MPR-Arsbabd/Ncchd MPR/Iar
Is Marker For: Strains:   MPR/Iar   WIAR.MPR-Arsbabd/Ncchd  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0223,385,154 - 23,543,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0242,559,079 - 42,717,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4224,067,560 - 24,223,821 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1223,988,194 - 24,144,190 (+)NCBI
Celera221,077,645 - 21,235,680 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Arsb
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2158
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE