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Gene: Plppr4 (phospholipid phosphatase related 4) Rattus norvegicus

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Symbol:

Plppr4

Name:

phospholipid phosphatase related 4

RGD ID:

727806

Description:

Enables lipid phosphatase activity and lysophosphatidic acid phosphatase activity. Involved in axonogenesis and phospholipid dephosphorylation. Located in external side of plasma membrane. Orthologous to human PLPPR4 (phospholipid phosphatase related 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2-lysophosphatidate phosphatase PLPPR4; brain-specific phosphatidic acid phosphatase-like protein 1; inactive 2-lysophosphatidate phosphatase PLPPR4; lipid phosphate phosphatase-related protein type 4; Lppr4; phospholipid phosphatase-related protein type 4; plasticity related gene 1; plasticity-related gene 1; Prg-1; Prg1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLPPR4 (phospholipid phosphatase related 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Plppr4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Plppr4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLPPR4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLPPR4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Plppr4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLPPR4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLPPR4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Plppr4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Plppr4 (phospholipid phosphatase related 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PLPPR4 (phospholipid phosphatase related 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Plppr4 (phospholipid phosphatase related 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plppr4a (phospholipid phosphatase related 4a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plpr-1	Alliance	DIOPT (Hieranoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plpr-1	Alliance	DIOPT (OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	plppr4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	208,056,206 - 208,097,191 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	208,056,211 - 208,097,191 (-)	Ensembl				GRCr8
mRatBN7.2	2	205,371,317 - 205,412,302 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	205,371,322 - 205,412,302 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	213,018,609 - 213,059,602 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	210,933,198 - 210,974,196 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	205,751,648 - 205,792,638 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	220,298,239 - 220,341,863 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	220,298,245 - 220,341,866 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	238,365,252 - 238,405,892 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	213,686,578 - 213,727,831 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	197,848,561 - 197,889,304 (-)	NCBI		Celera
RGSC_v3.1	2	213,649,335 - 213,690,585 (-)	NCBI
Cytogenetic Map	2	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

Cuprizon (EXP)

decabromodiphenyl ether (EXP)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

ferric oxide (EXP)

flurotyl (EXP)

folic acid (ISO)

geldanamycin (ISO)

iron dichloride (ISO)

lead(0) (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methotrexate (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

ozone (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP,ISO)

phenylmercury acetate (ISO)

poly(I:C) (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

triadimefon (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axonogenesis (IBA,IDA)

G protein-coupled receptor signaling pathway (ISO,ISS)

inner ear development (ISO)

lipid import into cell (IEA,ISO,ISS)

modulation of chemical synaptic transmission (IEA,ISO)

phospholipid dephosphorylation (IBA,IDA,ISO)

phospholipid metabolic process (IBA,IEA)

regulation of postsynapse organization (IEA,ISO)

regulation of synaptic transmission, glutamatergic (IEA,ISO,ISS)

signal transduction (IBA)

Cellular Component

external side of plasma membrane (IDA)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

plasma membrane (IBA,IEA)

postsynaptic density membrane (IEA,ISO,ISS)

Schaffer collateral - CA1 synapse (IEA,ISO)

Molecular Function

lipid phosphatase activity (IDA)

lysophosphatidic acid phosphatase activity (IMP,ISO,ISS)

phosphatidate phosphatase activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting.	Brauer AU, etal., Nat Neurosci 2003 Jun;6(6):572-8.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18643870	PMID:19059322	PMID:19766573	PMID:20167268	PMID:21795542	PMID:22871113	PMID:23015549	PMID:24038138	PMID:25931508

Genomics

Comparative Map Data

Plppr4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	208,056,206 - 208,097,191 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	208,056,211 - 208,097,191 (-)	Ensembl				GRCr8
mRatBN7.2	2	205,371,317 - 205,412,302 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	205,371,322 - 205,412,302 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	213,018,609 - 213,059,602 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	210,933,198 - 210,974,196 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	205,751,648 - 205,792,638 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	220,298,239 - 220,341,863 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	220,298,245 - 220,341,866 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	238,365,252 - 238,405,892 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	213,686,578 - 213,727,831 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	197,848,561 - 197,889,304 (-)	NCBI		Celera
RGSC_v3.1	2	213,649,335 - 213,690,585 (-)	NCBI
Cytogenetic Map	2	q42	NCBI

PLPPR4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	99,262,924 - 99,309,584 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	99,264,292 - 99,309,590 (+)	Ensembl			hg38	GRCh38
GRCh37	1	99,730,048 - 99,775,140 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	99,502,488 - 99,547,728 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	97,983,902 - 98,029,193 (+)	NCBI		Celera
Cytogenetic Map	1	p21.3-p21.2	NCBI
HuRef	1	97,852,810 - 97,898,096 (+)	NCBI		HuRef
CHM1_1	1	99,846,184 - 99,891,476 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	99,111,296 - 99,157,921 (+)	NCBI		T2T-CHM13v2.0

Plppr4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	117,112,794 - 117,154,525 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	117,112,788 - 117,154,525 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	117,319,145 - 117,360,876 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	117,319,139 - 117,360,876 (-)	Ensembl			mm10	GRCm38
MGSCv37	3	117,022,063 - 117,063,794 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	117,311,149 - 117,352,880 (-)	NCBI		MGSCv36	mm8
Celera	3	123,722,032 - 123,763,668 (-)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	50.57	NCBI

Plppr4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	4,091,165 - 4,114,376 (+)	Ensembl
ChiLan1.0	NW_004955435	4,085,918 - 4,112,207 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLPPR4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	127,720,740 - 127,766,341 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	126,875,286 - 126,920,897 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	101,919,714 - 101,965,146 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	100,640,187 - 100,685,483 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	100,640,187 - 100,685,483 (+)	Ensembl			panPan2	panpan1.1

PLPPR4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	50,553,769 - 50,594,298 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	50,554,949 - 50,594,383 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	53,237,104 - 53,277,408 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	50,906,076 - 50,946,382 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	50,906,113 - 50,946,341 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	50,599,385 - 50,639,586 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	50,578,764 - 50,619,057 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	51,011,414 - 51,051,742 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plppr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	108,444,124 - 108,485,378 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	462,583 - 503,874 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	462,595 - 503,770 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLPPR4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	118,713,994 - 118,752,224 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	118,713,987 - 118,752,499 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	130,278,777 - 130,316,328 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLPPR4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	33,996,027 - 34,042,145 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	33,996,021 - 34,042,004 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	24,010,104 - 24,055,697 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plppr4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624857	1,907,932 - 1,956,093 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624857	1,761,972 - 1,955,112 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plppr4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	42,373,554 - 42,412,327 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plppr4
364 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	776
Count of miRNA genes:	304
Interacting mature miRNAs:	402
Transcripts:	ENSRNOT00000022625
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204795005	249795005	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1302789	Stl26	Serum triglyceride level QTL 26	3.1	0.0035	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	206613059	226891081	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	196140964	251540988	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	205135267	250135267	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	188565047	233565047	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	192287802	229609668	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	192287802	221089121	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	202029709	236904960	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	205135267	225627153	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	186850607	231850607	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	203664411	248664411	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat

Markers in Region

AW526088

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	205,371,352 - 205,371,561 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	220,341,619 - 220,341,827	NCBI	Rnor6.0
Rnor_5.0	2	238,405,648 - 238,405,856	UniSTS	Rnor5.0
RGSC_v3.4	2	213,686,613 - 213,686,821	UniSTS	RGSC3.4
Celera	2	197,848,597 - 197,848,805	UniSTS
RH 3.4 Map	2	1489.3	UniSTS
Cytogenetic Map	2	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	9	62	155	75	74	43	33	43	6	266	122	11	127	80	80	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001001508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF541280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY266268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022625 ⟹ ENSRNOP00000022625

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	208,056,211 - 208,097,191 (-)	Ensembl
mRatBN7.2 Ensembl	2	205,371,322 - 205,412,302 (-)	Ensembl
Rnor_6.0 Ensembl	2	220,298,245 - 220,341,866 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114094 ⟹ ENSRNOP00000084199

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	208,056,211 - 208,096,760 (-)	Ensembl
mRatBN7.2 Ensembl	2	205,371,322 - 205,390,852 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000156852 ⟹ ENSRNOP00000109511

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	208,056,211 - 208,092,038 (-)	Ensembl

RefSeq Acc Id:

NM_001001508 ⟹ NP_001001508

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	208,056,206 - 208,097,191 (-)	NCBI
mRatBN7.2	2	205,371,317 - 205,412,302 (-)	NCBI
Rnor_6.0	2	220,298,239 - 220,341,863 (+)	NCBI
Rnor_5.0	2	238,365,252 - 238,405,892 (+)	NCBI
RGSC_v3.4	2	213,686,578 - 213,727,831 (-)	RGD
Celera	2	197,848,561 - 197,889,304 (-)	NCBI

Sequence:

show sequence

ATGCCCCAATTCACCCTCTCTCTTCAGATGCAGGCAAAAAATTCTCACTTTGTTCCTCGGCGGA
TTGGAGCTTTTTCTAGGTGCTTCCCTTGGAGTTACCTCCCTAGAGATCAGTAGTCAGGGCTGTC
ACGCTTGGGTAGCGGCCAGCTCCCAGTGAATTCCTTCTATGGCCTACTTGTCAGTATGAAATCT
GAGTTTTAATTTTGCACAGGTGGAGGTCTCTTTTGCTATGGGTAAGGTGGATAGCGGTGCCCAG
CAAGCTCCTGCTCTCTAGAAAGGCAACAAGAACCCCAGGTAGGAGACCAGGTGCCTTGGCTCCT
CAGCCTTGCTTCTGCAGAAACCAGGAGTGCCTCCCCCCACTATTTTTGACGTCAAGCTCAGACA
ACCAGCAGAGGAGCCTCACAGCTTGGGCGGTGGAGAGCCCAGGGAGAGTGGCAGGGAGGGGAAG
CCATCACAGCAACAGCTTGGAGGGGGAGCTGGCTATCACTTTCCCTCAAAATACGGACTAAAAC
CCGGCTGAAGAAGACCTGCGGGATCAGGGAAGCGCCGGGTTACTGCAAAGAAGGGCGGGGAAAA
GGAGGGGGCGCTGCATGCAGCGCGCTGGCTCCAGCGGTGCCCGCGGGGAATGTGACATCAGCGG
CACCGGGCGCTTGCGGCTGGAGCAGGCAGCTCGCCTCGGTGGCCGCGCAGTGCACACCTCACCC
ACGGGAGGACTCGGAGCCCGGCAGGTGGCCGGGATGTCGGCGAAGGAGAGGCCAAAGGGCAAAG
TGATCAAGGACAGCGTCACCCTCCTGCCCTGTTTCTATTTCGTTGAGTTGCCTATATTGGCGTC
ATCGGTGGTTAGTCTCTACTTCCTGGAACTCACAGATGTCTTCAAACCTGTGCACTCCGGATTC
AGTTGCTATGACAGGAGTCTTAGCATGCCGTACATTGAGCCAACCCAAGAGGCCATTCCATTCC
TCATGTTGCTTAGCTTGGCTTTTGCTGGACCTGCAATTACGATCATGGTGGGTGAAGGGATTCT
GTACTGCTGCCTCTCTAAAAGAAGAAATGGAGCTGGATTGGAGCCCAACATCAACGCCGGGGGC
TGCAACTTCAATTCCTTTCTCAGAAGAGCCGTCAGATTTGTTGGTGTCCACGTGTTTGGACTGT
GCTCCACAGCTCTCATTACGGATATCATACAGCTGTCCACAGGATATCAGGCACCATACTTTCT
GACTGTGTGCAAGCCCAATTACACCTCTCTGAATGTATCCTGCAAAGAAAATTCCTACATCGTG
GAAGACATTTGTTCGGGATCTGACCTTACAGTTATCAACAGTGGCAGAAAGTCATTCCCGTCCC
AGCATGCGACCCTCGCTGCCTTTGCTGCTGTGTATGTGTCCATGTACTTCAATTCCACATTAAC
TGACTCCTCCAAGCTCCTGAAACCTCTCTTGGTCTTCACATTTATCATCTGTGGAATCATCTGC
GGGCTAACACGGATCACTCAGTATAAGAACCATCCCGTCGATGTTTATTGTGGCTTTTTAATTG
GAGGAGGAATCGCGCTGTATTTGGGCCTGTATGCTGTAGGGAATTTTCTGCCTAGTGAAGACAG
CATGCTTCAGCACAGAGATGCCCTCAGGTCACTGACAGACCTCAATCAAGACCCCAGCAGGGTT
TTGTCAGCTAAAAATGGTAGCAGCGGTGATGGAATTGCTCACACAGAGGGTATTCTCAACCGAA
ATCACAGGGATGCAAGCTCCTTAACAAATCTGAAGAGGGCCAACGCTGACGTAGAGATCATCAC
TCCTAGGAGCCCCATGGGGAAGGAGAGCATGGTGACCTTCAGTAACACGCTGCCCAGGGCCAAC
ACCCCGTCCGTGGAAGACCCGGTGAGAAGAAACGCGAGCATTCACGCCTCTATGGATTCTGCCC
GGTCCAAGCAGCTCCTTACCCAGTGGAAGAGCAAGAACGAGAGTCGCAAGATGTCCCTGCAGGT
TATGGACTCTGAACCAGAAGGGCAGTCACCACCCAGGTCCATAGAAATGAGGTCCAGCTCAGAG
CCCTCGAGGGTGGGGGTGAATGGAGATCACCATGTCCCGGGCAATCAGTACCTCAAGATCCAGC
CTGGCACAGTTCCCGGGTGCAACAATAGTATGCCTGCAGGGCCACGTGTGTCCATCCAGTCCCG
CCCTGGCTCTTCCCAATTGGTGCACATCCCCGAGGAGACCCAGGAAAACATAAGCACCTCGCCC
AAGAGCAGTTCCGCACGGGCCAAGTGGCTGAAAGCAGCAGAGAAGACCGTGGCCTGTAACCGGG
GCAACAACCAGCCACGCATCATGCAGGTCATCGCCATGTCCAAGCAGCAGGGCGTGCTGCAGAG
CAGCCCCAAGAATGCCGAAGGTAGCACGGTCACCTGCACAGGCTCCATCCGCTACAAAACCCTG
ACTGACCACGAGCCGAGTGGCATTGTGCGAGTGGAGGCTCATCCCGAGAACAACAGGCCCATCA
TCCAGATTCCATCGTCCACCGAGGGCGAAGGCAGTGGCTCCTGGAAGTGGAAAGCTCCGGAGAA
GAGTAGCCTGCGCCAAACCTATGAGCTCAACGACCTCAACAGGGACTCGGAAAGCTGCGAGTCC
CTCAAAGACAGCTTTGGTTCTGGAGATCGCAAGAGAAGCAACATCGACAGCAATGAGCACCACC
ACCACGGCATCACAACCATCCGCGTGACCCCAGTGGAGGGCAGCGAGATAGGCTCAGAGACGCT
GTCTGTATCCTCCTCACGCGACTCCACCCTGCGCAGGAAGGGCAACATTATCTTGATCCCTGAA
AGAAGCAACAGCCCTGAAAACACAAGAAACATCTTCTACAAAGGAACCTCCCCCACGAGGGCTT
ATAAGGATTGAGTGACCGCCCTTCTTGTCATCATTTTGGTGACATCCCCACCCCCACCCCAAGA
CCACACATTTATTATAGTACCTTGTGCTCTTTTGGGTATTTTGTTGTTGTTTTGGTTTTGGTTT
TTTGTTTTCTTTTCTAGTGGATATGGAGAGCCTTCTTGCCCAACTAGATTGTTCACCATCAGCC
TGGAACTCTCACTGACCCACCACAGAAACCGTGGTGATTTTCCACCAAGGGAAAGGAAAAGCAC
AAAGCAAGACCCGAACTAATCTCATCATCTGAATAGTTCTTAAGGCCTGTCACTGAGACTTCGC
AGAGGGCAGTATTAGGATAAAGTGGTCTCCTCCGATGTATAGTATTTAACTTTCTGAATGTGCC
AACTTTGAAGTTTCTTTTTTTTTTTTTTCATTATAATTAGCGGTGGGAACCCAAAACACTACAG
GTTTCCCCGGCAGCAGAGGCCACGCAGTATTATATAGTATTTATTTTTGCAGACTCTGCACCAG
AAGAGCAGACTGGGCGGTGCTGATTACCACAGTACATCTACCATTTCAACTCTCAGACTCTGTG
TAGCTGTGAGAGAGTGGTGTACAACCCCCTTGTCAGAGAAATGCTACTTCATTCAGAAGACGCC
AGTGACTTTGTGGTAGCATAGGCCATTCTTGGCTTCCCTGTAGTGGCTCTCTCACAGTCAAAAA
GAAAAAAGAAAGAAAAAACTGGACAGGGTTCTGAGCATTTCTTTGAAAGATTCTTTGTTTTCAA
CATTTGAAAGTCTGTAGGGATGTTTTCGGTGAGACGGAACAACTAGTTCTCCGCATCGTTTTTC
TGCTTTTTATTTAAGTATTGGTAATGCTGGTTTCTGGTATCTTTTTTTTTTAGTGAGTGCATTT
GCATATTTAAAATACATTGTTTTAGAGAATATTTTGAAATTATTATAATCACATTTTCCATTTT
GTGGCTTCATCTTAGTTTATTAAGTTTTTTGAGGTTATGCACACCATTCTTCTATTTTAAGAAA
GCAACAGTGACCATTTACATTCCTTGTGCAAAATACACTGCTTCGAGGTCCTACGCAAGAAATA
TGAGCCAACGGTTGAAACTGTGCGTTCCATTGCCAGATACATTGGTCACATTCAAGATGTCTCC
AATCCGATGGCATAGGTTATCACATCAGTAAGCGATCCCCAAACTTCATTTTCTTCCAGAGCAT
TTCATTTTTGTGTTATCCTGATAATCACCATATCGGAGCCACCATGGGGGTGAGCTTGACTCCC
TTCCCTGACACACTTTTAACTGGACACCAACAGTAAGGACCTAGGCAAAGGCTAATTGATAGAT
AGAAGTGTATCACAGCATACATTTAGAAAGTGTATCTTCAAAACAGCAGACCAGGCAAAGCTTT
TGTGCTTAGAGTACTATTGACAGTTTTGGCTGCCTGTCTTGAATCTAGAACCTTGAGCCAAAAT
CAAAGGAAACCATACTGTTGATAGCAAGAAGATTACCACAAGATATTTTTGAAGTGTTTTCCCA
GGTTAGATGTTTAAAGAGTGGAGACATATATTTGGTCCTTGAAATTTGTTATAAAACCTTTCTC
ATGCCATGTCTTAAGAATTATAATGGACACTTGATGATTGCCAAGAGGGGGAGCAAAAACAGCG
AACAGCAGAGCTGGTTGGTCTGAACTCAGTGCAGCTTTCAGTGAGAACAAAAGCTGTCCAGCAA
AGAGTCACATCATTCATTCTCTAGCCTCTCCATTCAAAGGGCAGAGCTTTTTTTTTTTTTTAAG
AAAACTCAACCTCTTAAGGCATTAGGAATTTAGCTGAGACCAGCAGAATTGAAAACTCTGGCAA
TAAAATATAGGCTCAACCATAACCCTTCTGGCAAGTTCCTTCTCAGAGAAGGAAGTGGGAGTAA
AATGTGGCCTTCCCCACTTCTCTTACATCACCACTGTCACAATGTCCCCGCTGGCCCGGCCAGT
TCCTAGAGGGAAGGGTGGACTGGTTTTAGTACTCTGGAGAAAAAAAAAACCAAGCTGCAGTATT
TGAGGTGCAGTATGATATTTCCTAATCTTTCCTATTTCTTAACAAAAAAGATTTTAAAGCACTT
CTCTAGTCATTGAACTTTTGTTCTTTACATACTATTGATATATTCTTTTTCTACTCAAAGTGCC
AAAGGCTACAGTTTTTAAACGACTTAACAAATTGTACCACACTGTTAAGGAACTATAACGATAG
ACACTAGAATTCAGACCTCTGCATGTATATTTGATAACACATCTTTTGTAAAAAATAAATAATT
ACAAAAAATTTGTTTACATTCCACTGGTACCTTAATTTAAAAGAAATCAGACTAACAGGTGGTA
TCTCTTCTTAGTGTTCTATTTATCTTACTTGCTAACGAGAGCAATTCTTCTTTTGTTAGGCTGT
GCTTTATTGATGAAACCGAGTATTGAATAAAGAGAGTTAATTATCTTTTTAAAGTAAATAAAAC
TATGAATATATAATATATATGAAGTATCGTGTTTAATAAAAATGTTATGCAATGTTTTCCAAAC
TGATAAAGTTTGTAAAGTGCTATAAATGTATTTTGTTAAGTACAGATCAAAGCTATCGTGTGAG
TATATTGTGCTGGCATCATAGAAATAAAGATTAGATTTCTTCATCAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001001508	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP41101	(Get FASTA)	NCBI Sequence Viewer
	AAP57769	(Get FASTA)	NCBI Sequence Viewer
	EDL82053	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022625
GenBank Protein	Q7TMB7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001001508 ⟸ NM_001001508

- UniProtKB:

Q7TMB7 (UniProtKB/Swiss-Prot), G3V864 (UniProtKB/TrEMBL), A6HVB7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQRAGSSGARGECDISGTGRLRLEQAARLGGRAVHTSPTGGLGARQVAGMSAKERPKGKVIKDS
VTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLS
LAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTAL
ITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATL
AAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIA
LYLGLYAVGNFLPSEDSMLQHRDALRSLTDLNQDPSRVLSAKNGSSGDGIAHTEGILNRNHRDA
SSLTNLKRANADVEIITPRSPMGKESMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQL
LTQWKSKNESRKMSLQVMDSEPEGQSPPRSIEMRSSSEPSRVGVNGDHHVPGNQYLKIQPGTVP
GCNNSMPAGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRGNNQP
RIMQVIAMSKQQGVLQSSPKNAEGSTVTCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPS
STEGEGSGSWKWKAPEKSSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGIT
TIRVTPVEGSEIGSETLSVSSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD

hide sequence

Ensembl Acc Id:

ENSRNOP00000022625 ⟸ ENSRNOT00000022625

Ensembl Acc Id:

ENSRNOP00000084199 ⟸ ENSRNOT00000114094

Ensembl Acc Id:

ENSRNOP00000109511 ⟸ ENSRNOT00000156852

Protein Domains

Phosphatidic acid phosphatase type 2/haloperoxidase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TMB7-F1-model_v2	AlphaFold	Q7TMB7	1-766	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727806	AgrOrtholog
BioCyc Gene	G2FUF-51476	BioCyc
Ensembl Genes	ENSRNOG00000016872	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000022625	ENTREZGENE
Gene3D-CATH	Phosphatidic acid phosphatase type 2/haloperoxidase	UniProtKB/Swiss-Prot
InterPro	P_Acid_Pase_2/haloperoxi_sf	UniProtKB/Swiss-Prot
	P_Acid_Pase_2/haloperoxidase	UniProtKB/Swiss-Prot
	PLPP	UniProtKB/Swiss-Prot
NCBI Gene	295401	ENTREZGENE
PANTHER	PTHR10165	UniProtKB/Swiss-Prot
	PTHR10165:SF13	UniProtKB/Swiss-Prot
Pfam	PAP2	UniProtKB/Swiss-Prot
PhenoGen	Plppr4	PhenoGen
RatGTEx	ENSRNOG00000016872	RatGTEx
SMART	acidPPc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48317	UniProtKB/Swiss-Prot
UniProt	A0A8I6A0S8_RAT	UniProtKB/TrEMBL
	A0ABK0LYE2_RAT	UniProtKB/TrEMBL
	A6HVB7	ENTREZGENE, UniProtKB/TrEMBL
	G3V864	ENTREZGENE, UniProtKB/TrEMBL
	PLPR4_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-10-26	Plppr4	phospholipid phosphatase related 4	Lppr4	lipid phosphate phosphatase-related protein type 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-11-02	Lppr4	lipid phosphate phosphatase-related protein type 4	Lppr4	plasticity related gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-14	Lppr4	plasticity related gene 1	Prg-1	plasticity-related gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-07-23	Prg-1	plasticity-related gene 1	Lppr4	plasticity related gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Lppr4	plasticity related gene 1	Prg1	plasticity related gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-09-30	Prg1				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localizes to the plasma membranes of outgrowing axons	1299556
gene_process	attenuates phospholipid-induced axon collapse in neurons thereby facilitating axonal outgrowth in the hippocampus	1299556
gene_process	acts as an ectoenzyme	1299556

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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