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| # | Reference Title | Reference Citation |
| 1. | Evidence for four cytoplasmic dynein heavy chain isoforms in rat testis. | Criswell PS and Asai DJ, Mol Biol Cell. 1998 Feb;9(2):237-47. doi: 10.1091/mbc.9.2.237. |
| 2. | A novel cytoplasmic dynein heavy chain: expression of DHC1b in mammalian ciliated epithelial cells. | Criswell PS, etal., J Cell Sci. 1996 Jul;109 ( Pt 7):1891-8. |
| 3. | NEK1 and DYNC2H1 are both involved in short rib polydactyly Majewski type but not in Beemer Langer cases. | El Hokayem J, etal., J Med Genet. 2012 Apr;49(4):227-33. doi: 10.1136/jmedgenet-2011-100717. |
| 4. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 6. | Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells. | Mikami A, etal., J Cell Sci. 2002 Dec 15;115(Pt 24):4801-8. |
| 7. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 8. | Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. | Neesen J, etal., Gene 1997 Oct 24;200(1-2):193-202. |
| 9. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 10. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 11. | GOA pipeline | RGD automated data pipeline |
| 12. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 13. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 14. | Identification and molecular evolution of new dynein-like protein sequences in rat brain. | Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93. |
| PMID:8666668 | PMID:8812413 | PMID:12802074 | PMID:15755804 | PMID:15866890 | PMID:16061793 | PMID:16229832 | PMID:17289665 | PMID:18488998 | PMID:19056867 | PMID:21525035 | PMID:21552265 |
| PMID:21723285 | PMID:22689656 | PMID:22871113 | PMID:25807483 | PMID:25830415 |
| Dync2h1 (Rattus norvegicus - Norway rat) |
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| DYNC2H1 (Homo sapiens - human) |
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| Dync2h1 (Mus musculus - house mouse) |
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| Dync2h1 (Chinchilla lanigera - long-tailed chinchilla) |
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| DYNC2H1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DYNC2H1 (Canis lupus familiaris - dog) |
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| Dync2h1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DYNC2H1 (Sus scrofa - pig) |
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| DYNC2H1 (Chlorocebus sabaeus - green monkey) |
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| Dync2h1 (Heterocephalus glaber - naked mole-rat) |
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| Dync2h1 (Rattus rattus - black rat) |
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.
Variants in Dync2h1
1265 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| RH134854 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 165 | 91 | 90 | 59 | 88 | 59 | 6 | 352 | 188 | 11 | 144 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_023024 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_063266103 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063266104 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063266105 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063266106 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010054024 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AB041881 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| D26495 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000008 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U61748 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000044174 ⟹ ENSRNOP00000043252 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000112659 ⟹ ENSRNOP00000097714 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000130124 ⟹ ENSRNOP00000101717 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_023024 ⟹ NP_075413 | ||||||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_063266103 ⟹ XP_063122173 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063266104 ⟹ XP_063122174 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063266105 ⟹ XP_063122175 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063266106 ⟹ XP_063122176 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_010054024 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_075413 | (Get FASTA) | NCBI Sequence Viewer |
| XP_063122173 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063122174 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063122175 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063122176 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAC52802 | (Get FASTA) | NCBI Sequence Viewer |
| BAA05503 | (Get FASTA) | NCBI Sequence Viewer | |
| BAA97048 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000043252 | ||
| ENSRNOP00000097714 | |||
| GenBank Protein | Q9JJ79 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_075413 ⟸ NM_023024 |
| - UniProtKB: | Q9JJ79 (UniProtKB/Swiss-Prot), Q63167 (UniProtKB/Swiss-Prot), P70576 (UniProtKB/Swiss-Prot), D3ZBB8 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000043252 ⟸ ENSRNOT00000044174 |
| Ensembl Acc Id: | ENSRNOP00000097714 ⟸ ENSRNOT00000112659 |
| RefSeq Acc Id: | XP_063122176 ⟸ XM_063266106 |
| - Peptide Label: | isoform X4 |
| - UniProtKB: | Q9JJ79 (UniProtKB/Swiss-Prot), Q63167 (UniProtKB/Swiss-Prot), P70576 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063122174 ⟸ XM_063266104 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | Q9JJ79 (UniProtKB/Swiss-Prot), Q63167 (UniProtKB/Swiss-Prot), P70576 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063122175 ⟸ XM_063266105 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | Q9JJ79 (UniProtKB/Swiss-Prot), Q63167 (UniProtKB/Swiss-Prot), P70576 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063122173 ⟸ XM_063266103 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q9JJ79 (UniProtKB/Swiss-Prot), Q63167 (UniProtKB/Swiss-Prot), P70576 (UniProtKB/Swiss-Prot), A0A8I6ANN6 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000101717 ⟸ ENSRNOT00000130124 |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13695729 | ||||||||
| Promoter ID: | EPDNEW_R6253 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Dync2h1_1 | ||||||||
| Description: | dynein cytoplasmic 2 heavy chain 1 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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| Database | Acc Id | Source(s) |
| AGR Gene | RGD:71042 | AgrOrtholog |
| BioCyc Gene | G2FUF-31795 | BioCyc |
| Ensembl Genes | ENSRNOG00000032070 | Ensembl, ENTREZGENE |
| Ensembl Transcript | ENSRNOT00000044174 | ENTREZGENE |
| ENSRNOT00000112659 | ENTREZGENE | |
| Gene3D-CATH | 1.10.8.1220 | UniProtKB/Swiss-Prot |
| 1.10.8.710 | UniProtKB/Swiss-Prot | |
| 1.10.8.720 | UniProtKB/Swiss-Prot | |
| 1.20.1270.280 | UniProtKB/Swiss-Prot | |
| 1.20.140.100 | UniProtKB/Swiss-Prot | |
| 1.20.58.1120 | UniProtKB/Swiss-Prot | |
| 1.20.920.20 | UniProtKB/Swiss-Prot | |
| 1.20.920.30 | UniProtKB/Swiss-Prot | |
| 3.10.490.20 | UniProtKB/Swiss-Prot | |
| 3.20.180.20 | UniProtKB/Swiss-Prot | |
| 3.40.50.300 | UniProtKB/Swiss-Prot | |
| 6.10.140.1060 | UniProtKB/Swiss-Prot | |
| InterPro | AAA+_ATPase | UniProtKB/Swiss-Prot |
| AAA_6 | UniProtKB/Swiss-Prot | |
| AAA_9 | UniProtKB/Swiss-Prot | |
| AAA_lid_11 | UniProtKB/Swiss-Prot | |
| AAA_lid_11_sf | UniProtKB/Swiss-Prot | |
| DHC_fam | UniProtKB/Swiss-Prot | |
| DYNC2H1-like_lid | UniProtKB/Swiss-Prot | |
| DYNC2H1_AAA_dom | UniProtKB/Swiss-Prot | |
| Dynein_2_C | UniProtKB/Swiss-Prot | |
| Dynein_2_N | UniProtKB/Swiss-Prot | |
| Dynein_AAA1S | UniProtKB/Swiss-Prot | |
| Dynein_C | UniProtKB/Swiss-Prot | |
| Dynein_C_barrel | UniProtKB/Swiss-Prot | |
| Dynein_HC_stalk | UniProtKB/Swiss-Prot | |
| Dynein_heavy_chain_D4_dom | UniProtKB/Swiss-Prot | |
| Dynein_heavy_D6_P-loop | UniProtKB/Swiss-Prot | |
| Dynein_heavy_dom-1 | UniProtKB/Swiss-Prot | |
| Dynein_heavy_dom-2 | UniProtKB/Swiss-Prot | |
| P-loop_NTPase | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:65209 | UniProtKB/Swiss-Prot |
| NCBI Gene | 65209 | ENTREZGENE |
| PANTHER | CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 | UniProtKB/Swiss-Prot |
| MALE FERTILITY FACTOR KL5 | UniProtKB/Swiss-Prot | |
| Pfam | AAA_6 | UniProtKB/Swiss-Prot |
| AAA_7 | UniProtKB/Swiss-Prot | |
| AAA_8 | UniProtKB/Swiss-Prot | |
| AAA_9 | UniProtKB/Swiss-Prot | |
| AAA_lid_11 | UniProtKB/Swiss-Prot | |
| DHC_N1 | UniProtKB/Swiss-Prot | |
| DHC_N2 | UniProtKB/Swiss-Prot | |
| DYN_lid | UniProtKB/Swiss-Prot | |
| DYNC2H1_AAA_dom | UniProtKB/Swiss-Prot | |
| Dynein_C | UniProtKB/Swiss-Prot | |
| Dynein_heavy | UniProtKB/Swiss-Prot | |
| PF12777 | UniProtKB/Swiss-Prot | |
| PhenoGen | Dync2h1 | PhenoGen |
| RatGTEx | ENSRNOG00000032070 | RatGTEx |
| SMART | AAA | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot |
| UniProt | A0A8I6ANN6 | ENTREZGENE, UniProtKB/TrEMBL |
| A0ABK0LEE7_RAT | UniProtKB/TrEMBL | |
| D3ZBB8 | ENTREZGENE, UniProtKB/TrEMBL | |
| DYHC2_RAT | UniProtKB/Swiss-Prot | |
| P70576 | ENTREZGENE | |
| Q63167 | ENTREZGENE | |
| Q9JJ79 | ENTREZGENE | |
| UniProt Secondary | P70576 | UniProtKB/Swiss-Prot |
| Q63167 | UniProtKB/Swiss-Prot |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2021-03-09 | Dync2h1 | dynein cytoplasmic 2 heavy chain 1 | LOC103689995 | cytoplasmic dynein 2 heavy chain 1-like | Data merged from RGD:9147056 | 737654 | PROVISIONAL |
| 2014-08-25 | LOC103689995 | cytoplasmic dynein 2 heavy chain 1-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2008-02-18 | Dync2h1 | dynein cytoplasmic 2 heavy chain 1 | Dnch2 | dynein, cytoplasmic, heavy polypeptide 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2004-09-10 | Dnch2 | dynein, cytoplasmic, heavy polypeptide 2 | dynein, cytoplasmic, heavy chain 2 | Name updated | 1299863 | APPROVED | |
| 2002-07-09 | Dnch2 | dynein, cytoplasmic, heavy chain 2 | Symbol and Name updated to reflect Human and Mouse nomenclature | 70877 | APPROVED |
| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expression in adult highest in testis, and also detectable in brain and ovary by Northern blot; expression in neonatal brain highest at birth | 632520 |
| gene_transcript | may have splice varients in rat brain | 632520 |