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Gene: Decr2 (2,4-dienoyl-CoA reductase 2) Rattus norvegicus

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Symbol:

Decr2

Name:

2,4-dienoyl-CoA reductase 2

RGD ID:

71002

Description:

Enables 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in unsaturated fatty acid biosynthetic process. Located in peroxisomal membrane. Orthologous to human DECR2 (2,4-dienoyl-CoA reductase 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2,4-dienoyl CoA reductase 2, peroxisomal; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; DCR-AKL; Dcrakl; peroxisomal 2,4-dienoyl-CoA reductase; peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; putativeperoxisomal2,4-dienoyl-CoAreductase; putativeperoxisomal24-dienoyl-CoAreductase; pVI-AKL

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DECR2 (2,4-dienoyl-CoA reductase 2)	HGNC	EggNOG, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Decr2 (2-4-dienoyl-Coenzyme A reductase 2, peroxisomal)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Decr2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DECR2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DECR2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Decr2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DECR2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DECR2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Decr2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Decr2 (2,4-dienoyl-CoA reductase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RAB11FIP3 (RAB11 family interacting protein 3)	HGNC	Ensembl
Homo sapiens (human):	NME4 (NME/NM23 nucleoside diphosphate kinase 4)	HGNC	EggNOG
Homo sapiens (human):	PWWP2A (PWWP domain containing 2A)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DECR2 (2,4-dienoyl-CoA reductase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DECR2 (2,4-dienoyl-CoA reductase 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Decr2 (2-4-dienoyl-Coenzyme A reductase 2, peroxisomal)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	decr2 (2,4-dienoyl CoA reductase 2, peroxisomal)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	decr2 (2,4-dienoyl CoA reductase 2, peroxisomal)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SPS19	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	decr2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	decr2	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	15,609,389 - 15,617,779 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	15,611,092 - 15,617,397 (-)	Ensembl				GRCr8
mRatBN7.2	10	15,104,907 - 15,113,281 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	15,002,926 - 15,118,479 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	19,844,315 - 19,852,298 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	19,333,200 - 19,341,185 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	14,832,983 - 14,841,013 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	15,451,850 - 15,460,227 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	15,431,638 - 15,465,413 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	15,265,550 - 15,273,903 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	15,350,593 - 15,358,640 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	14,773,344 - 14,781,377 (-)	NCBI		Celera
RGSC_v3.1	10	15,351,563 - 15,359,609 (-)	NCBI
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3,3',5-triiodo-L-thyronine (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

actinomycin D (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bexarotene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

chromium(6+) (ISO)

cisplatin (ISO)

clofibrate (EXP)

clofibric acid (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dichloroacetic acid (ISO)

dicyclanil (ISO)

dimethyl sulfoxide (ISO)

diquat (ISO)

elemental selenium (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenofibrate (EXP)

flavonoids (EXP)

flutamide (EXP)

gemfibrozil (EXP)

glafenine (EXP)

gliotoxin (EXP)

glutathione (EXP)

GW 7647 (ISO)

indometacin (EXP)

isobutanol (ISO)

ivermectin (ISO)

leflunomide (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

microcystin-LR (ISO)

Muraglitazar (EXP)

NADP zwitterion (ISO)

NADP(+) (ISO)

nefazodone (EXP)

nimesulide (EXP)

Nutlin-3 (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (EXP,ISO)

rotenone (EXP)

selenium atom (ISO)

sodium arsenite (EXP,ISO)

sunitinib (ISO)

temozolomide (ISO)

Tesaglitazar (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

tetrahydropalmatine (ISO)

thiram (ISO)

trichloroethene (EXP,ISO)

triphenyl phosphate (ISO)

troglitazone (EXP,ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid catabolic process (IEA)

fatty acid metabolic process (IBA,IEA)

lipid metabolic process (IEA)

unsaturated fatty acid biosynthetic process (IEA,ISO)

Cellular Component

cleavage furrow (IEA)

midbody (IEA)

peroxisomal membrane (IDA,IEA)

peroxisome (IBA,IDA,IEA)

recycling endosome membrane (IEA)

Molecular Function

2,4-dienoyl-CoA reductase (NADPH) activity (IBA,IDA,IEA,ISO)

calcium ion binding (IEA)

oxidoreductase activity (IEA)

protein binding (ISO)

trans-2-enoyl-CoA reductase (NADPH) activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology.	Amery L, etal., Comb Chem High Throughput Screen. 2001 Nov;4(7):545-52.
2.	Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase.	Fransen M, etal., Biochem J 1999 Jun 1;340 ( Pt 2):561-8.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.	Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5.	Gene Data Set	MGD Curation, June 12, 2002
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:10811639	PMID:11514237	PMID:15489334	PMID:20178365

Genomics

Comparative Map Data

Decr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	15,609,389 - 15,617,779 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	15,611,092 - 15,617,397 (-)	Ensembl				GRCr8
mRatBN7.2	10	15,104,907 - 15,113,281 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	15,002,926 - 15,118,479 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	19,844,315 - 19,852,298 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	19,333,200 - 19,341,185 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	14,832,983 - 14,841,013 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	15,451,850 - 15,460,227 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	15,431,638 - 15,465,413 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	15,265,550 - 15,273,903 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	15,350,593 - 15,358,640 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	14,773,344 - 14,781,377 (-)	NCBI		Celera
RGSC_v3.1	10	15,351,563 - 15,359,609 (-)	NCBI
Cytogenetic Map	10	q12	NCBI

DECR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	401,885 - 412,482 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	401,854 - 412,492 (+)	Ensembl			hg38	GRCh38
GRCh37	16	451,885 - 462,482 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	391,859 - 402,488 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	16	391,858 - 402,487	NCBI
Celera	16	652,405 - 662,884 (+)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	370,920 - 381,537 (+)	NCBI		HuRef
CHM1_1	16	451,798 - 462,431 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	398,130 - 408,668 (+)	NCBI		T2T-CHM13v2.0

Decr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	26,300,182 - 26,309,096 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	26,300,182 - 26,309,311 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	26,081,208 - 26,090,322 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	26,081,208 - 26,090,337 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	26,218,156 - 26,227,109 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	25,808,811 - 25,817,764 (-)	NCBI		MGSCv36	mm8
Celera	17	26,615,219 - 26,624,120 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	13.06	NCBI

Decr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	16,797,190 - 16,807,199 (-)	Ensembl
ChiLan1.0	NW_004955442	16,799,927 - 16,807,199 (-)	NCBI	ChiLan1.0	ChiLan1.0

DECR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	631,096 - 642,162 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	4,420,568 - 4,430,821 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	16	395,041 - 406,832 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	395,158 - 405,928 (+)	Ensembl			panPan2	panpan1.1

DECR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	40,108,878 - 40,118,760 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	40,111,215 - 40,115,726 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	41,371,650 - 41,381,329 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	40,450,318 - 40,460,010 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	40,450,920 - 40,460,105 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	40,138,713 - 40,148,393 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	40,098,911 - 40,108,594 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	40,578,136 - 40,587,824 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Decr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	112,444,262 - 112,454,980 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	547,063 - 552,914 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	542,365 - 553,541 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DECR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	41,295,648 - 41,304,032 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	41,291,038 - 41,304,044 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	41,124,047 - 41,137,274 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DECR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	342,006 - 357,369 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	342,038 - 357,392 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666068	30,819,836 - 30,830,433 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Decr2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	1,238,173 - 1,244,374 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624913	1,237,797 - 1,246,723 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Decr2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	3,341,913 - 3,351,033 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Decr2
73 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	47
Count of miRNA genes:	44
Interacting mature miRNAs:	44
Transcripts:	ENSRNOT00000027518
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
631828	Alc5	Alcohol consumption QTL 5	2.4		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	1	17749933	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat

Markers in Region

RH128482

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	15,114,722 - 15,114,938 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	15,461,666 - 15,461,881	NCBI	Rnor6.0
Rnor_5.0	10	15,275,366 - 15,275,581	UniSTS	Rnor5.0
RGSC_v3.4	10	15,360,409 - 15,360,624	UniSTS	RGSC3.4
Celera	10	14,783,146 - 14,783,361	UniSTS
RH 3.4 Map	10	155.0	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	12	61	130	57	60	41	80	41	292	162	11	121	71	73	19	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_171996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF044574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC070959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027439 ⟹ ENSRNOP00000027439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,507,427 - 15,533,831 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,002,926 - 15,034,733 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000027518 ⟹ ENSRNOP00000027518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,611,092 - 15,617,397 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,106,610 - 15,113,068 (-)	Ensembl
Rnor_6.0 Ensembl	10	15,451,852 - 15,459,897 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000027593 ⟹ ENSRNOP00000027593

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	15,114,624 - 15,118,479 (-)	Ensembl
Rnor_6.0 Ensembl	10	15,461,552 - 15,465,413 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077826 ⟹ ENSRNOP00000068775

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	15,084,691 - 15,118,479 (-)	Ensembl
Rnor_6.0 Ensembl	10	15,431,638 - 15,465,404 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098691 ⟹ ENSRNOP00000082618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,507,151 - 15,591,173 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,002,926 - 15,086,708 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100008 ⟹ ENSRNOP00000095636

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,611,092 - 15,617,397 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,106,610 - 15,113,081 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100345 ⟹ ENSRNOP00000080945

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,507,151 - 15,591,173 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,002,926 - 15,086,708 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104441 ⟹ ENSRNOP00000093315

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,611,092 - 15,617,346 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,106,610 - 15,112,864 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117914 ⟹ ENSRNOP00000095174

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,507,151 - 15,591,173 (-)	Ensembl
mRatBN7.2 Ensembl	10	15,002,926 - 15,086,708 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165479 ⟹ ENSRNOP00000110670

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,507,151 - 15,591,031 (-)	Ensembl

RefSeq Acc Id:

NM_171996 ⟹ NP_741993

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,436 (-)	NCBI
mRatBN7.2	10	15,104,907 - 15,112,954 (-)	NCBI
Rnor_6.0	10	15,451,850 - 15,459,897 (-)	NCBI
Rnor_5.0	10	15,265,550 - 15,273,903 (-)	NCBI
RGSC_v3.4	10	15,350,593 - 15,358,640 (-)	RGD
Celera	10	14,773,344 - 14,781,377 (-)	RGD

Sequence:

show sequence

GCGAGCAACCCGCAAAACGTTGTGCATTGCGTTGAAAAGGTGCATCTGGTTCCCGATTCTACTC
CCCACCCGCGACCGCACACAGCAAACATGACCCAGCAGCCGCCTGACGTTGAGGAGGATGACTG
TCTTTCTGAATACCACCACCTCTTCTGCCCGGACCTTCTCCAGGACAAAGTGGCTTTTATCACT
GGTGGTGGTTCTGGGATTGGCTTCCGGATCGCCGAGATTTTCATGAGGCATGGCTGCCACACTG
TCATCGTCAGCAGGAGTCTGCCGAGAGTGTCCGAGGCTGCTAAGAAGTTGGTTGCTGCCACTGG
AAAGCGGTGTCTCCCTCTGTCTATGGATGTCCGAGTTCCCCCAGCTGTCATGGCTGCTGTGGAC
CAAGCGCTGAAAGAATTTGGCAAAATCGACATCCTCATTAACTGTGCTGCAGGGAACTTTTTAT
GCCCTGCCAGTGCATTGTCTTTCAATGCCTTTAAGACTGTGGTGGACATTGACACCCTTGGCAC
CTTCAATGTGTCTCGTGTGCTTTATGAGAAGTTCTTCCGGGACCATGGAGGAGTGATCGTGAAC
ATTACCGCCACCCTCAGTATGCGGGGGCAGGTGCTGCAGCTCCATGCAGGCGCTGCCAAGGCGG
CTGTGGATGCTATGACGCGACACTTGGCTGTGGAGTGGGGTCCCCAGAATATCCGTGTCAACAG
CCTGGCTCCTGGTGCCATCAGCGGCACTGAGGGTCTGCGGAGATTAGGAGGCCCCAAGGCCAGT
TCGAAATTTAAGTATCTTTCAAGTCCTATTCCAAGACTCGGAACCAAGACAGAAATCGCCCACA
GCGTGCTGTACCTAGCCAGCCCTCTGGCTTCCTATGTCTCAGGGATTGTGTTGGTGGTTGATGG
TGGTAGCTGGATGACGCTCCCAAATGACATTGGGCGACTGCTAGAGTTTGAATCCTCCTCTGCT
AAGCTGTAGTGTTTGAAGAGCACACCCAAGGCTTCAAGCATGTTAAAGCAACAGAATCAACTGA
ACTACGTCCTCTACCCCAGGATACCTTTTTTGACACATAAACATTGATTGCGCTTAAGAAAGTT
GTACTGAGGAGGCCGTGTTCTTCATGGGGAAGGCTTCCTGTCTCACATAGGTCTATAGTCACAC
GAGGAATGTTGAATCTGATTGGGAAATCCAAGCCCACCTGCCCTTCCTCCGGGATCAAGCTATT
TCCAAGCTCTGCCTCTCCTTTGCCCACATCCTGAGTAGAAATGGCCGGATTGTGAGCCTAGCCT
GATACTTGCTTACAGTATCTGAAGAGTTACTATGATTTTACCAGAAAAAAAAAATGCACTTTCT
TGTAAAAAAAAAATCATCTTTTTTACTGTAAAAATAGCTGAGTTGGAATTTGTAAAAGTTTCTA
GAAAGAAAATTTAAAAGATTGCTGACTGATTCTGTCACTGAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006246024 ⟹ XP_006246086

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,779 (-)	NCBI
mRatBN7.2	10	15,104,907 - 15,113,281 (-)	NCBI
Rnor_6.0	10	15,451,850 - 15,460,227 (-)	NCBI
Rnor_5.0	10	15,265,550 - 15,273,903 (-)	NCBI

Sequence:

show sequence

GCACTGGGAGGGAGTGTCCAAAATTGTCCGGAGTCCCGACTTCCACGGCTGATACCACGCCACC
CAGCCAGCTTGGGTACATGGACTAAGCGGCTGCACCAACACCAACTGGGAAAGGAAACCGAATT
CAACTGGCCGGAGCACCCCTCTACCTCTTGCCTCCTCCCAATTCGCAGTCCCAGCAGGCTGCGC
GCCACCGAGGGTGGGGCCTGGTTGAGTGGGAAGAGGTGGAAGCTGGGAGTAGAAGGAAGGTGCA
TCTGGTTCCCGATTCTACTCCCCACCCGCGACCGCACACAGCAAACATGACCCAGCAGCCGCCT
GACGTTGAGGAGGATGACTGTCTTTCTGAATACCACCACCTCTTCTGCCCGGACCTTCTCCAGG
ACAAAGTGGCTTTTATCACTGGTGGTGGTTCTGGGATTGGCTTCCGGATCGCCGAGATTTTCAT
GAGGCATGGCTGCCACACTGTCATCGTCAGCAGGAGTCTGCCGAGAGTGTCCGAGGCTGCTAAG
AAGTTGGTTGCTGCCACTGGAAAGCGGTGTCTCCCTCTGTCTATGGATGTCCGAGTTCCCCCAG
CTGTCATGGCTGCTGTGGACCAAGCGCTGAAAGAATTTGGCAAAATCGACATCCTCATTAACTG
TGCTGCAGGGAACTTTTTATGCCCTGCCAGTGCATTGTCTTTCAATGCCTTTAAGACTGTGGTG
GACATTGACACCCTTGGCACCTTCAATGTGTCTCGTGTGCTTTATGAGAAGTTCTTCCGGGACC
ATGGAGGAGTGATCGTGAACATTACCGCCACCCTCAGTATGCGGGGGCAGGTGCTGCAGCTCCA
TGCAGGCGCTGCCAAGGCGGCTGTGGATGCTATGACGCGACACTTGGCTGTGGAGTGGGGTCCC
CAGAATATCCGTGTCAACAGCCTGGCTCCTGGTGCCATCAGCGGCACTGAGGGTCTGCGGAGAT
TAGGAGGCCCCAAGGCCAGTTCGAAATTTAAGTATCTTTCAAGTCCTATTCCAAGACTCGGAAC
CAAGACAGAAATCGCCCACAGCGTGCTGTACCTAGCCAGCCCTCTGGCTTCCTATGTCTCAGGG
ATTGTGTTGGTGGTTGATGGTGGTAGCTGGATGACGCTCCCAAATGACATTGGGCGACTGCTAG
AGTTTGAATCCTCCTCTGCTAAGCTGTAGTGTTTGAAGAGCACACCCAAGGCTTCAAGCATGTT
AAAGCAACAGAATCAACTGAACTACGTCCTCTACCCCAGGATACCTTTTTTGACACATAAACAT
TGATTGCGCTTAAGAAAGTTGTACTGAGGAGGCCGTGTTCTTCATGGGGAAGGCTTCCTGTCTC
ACATAGGTCTATAGTCACACGAGGAATGTTGAATCTGATTGGGAAATCCAAGCCCACCTGCCCT
TCCTCCGGGATCAAGCTATTTCCAAGCTCTGCCTCTCCTTTGCCCACATCCTGAGTAGAAATGG
CCGGATTGTGAGCCTAGCCTGATACTTGCTTACAGTATCTGAAGAGTTACTATGATTTTACCAG
AAAAAAAAAATGCACTTTCTTGTAAAAAAAAAATCATCTTTTTTACTGTAAAAATAGCTGAGTT
GGAATTTGTAAAAGTTTCTAGAAAGAAAATTTAAAAGATTGCTGACTGATTCTGTCACTGAA

hide sequence

RefSeq Acc Id:

XM_039086793 ⟹ XP_038942721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,761 (-)	NCBI
mRatBN7.2	10	15,104,907 - 15,113,003 (-)	NCBI

RefSeq Acc Id:

XM_039086794 ⟹ XP_038942722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,488 (-)	NCBI
mRatBN7.2	10	15,104,907 - 15,113,003 (-)	NCBI

RefSeq Acc Id:

XM_039086795 ⟹ XP_038942723

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,491 (-)	NCBI
mRatBN7.2	10	15,104,907 - 15,113,006 (-)	NCBI

RefSeq Acc Id:

XM_063269816 ⟹ XP_063125886

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,609,389 - 15,617,759 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_741993	(Get FASTA)	NCBI Sequence Viewer
	XP_006246086	(Get FASTA)	NCBI Sequence Viewer
	XP_038942721	(Get FASTA)	NCBI Sequence Viewer
	XP_038942722	(Get FASTA)	NCBI Sequence Viewer
	XP_038942723	(Get FASTA)	NCBI Sequence Viewer
	XP_063125886	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD02333	(Get FASTA)	NCBI Sequence Viewer
	AAH70959	(Get FASTA)	NCBI Sequence Viewer
	EDM03991	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027518
	ENSRNOP00000027518.5
GenBank Protein	Q9Z2M4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_741993 ⟸ NM_171996

- UniProtKB:

Q9Z2M4 (UniProtKB/Swiss-Prot), A6HD86 (UniProtKB/TrEMBL), A0A8I6AJE6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTQQPPDVEEDDCLSEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPR
VSEAAKKLVAATGKRCLPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFN
AFKTVVDIDTLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHL
AVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPL
ASYVSGIVLVVDGGSWMTLPNDIGRLLEFESSSAKL

hide sequence

RefSeq Acc Id:	XP_006246086 ⟸ XM_006246024
- Peptide Label:	isoform X1
- UniProtKB:	Q9Z2M4 (UniProtKB/Swiss-Prot), A6HD86 (UniProtKB/TrEMBL), A0A8I6AJE6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTQQPPDVEEDDCLSEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPR VSEAAKKLVAATGKRCLPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFN AFKTVVDIDTLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHL AVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPL ASYVSGIVLVVDGGSWMTLPNDIGRLLEFESSSAKL hide sequence

Ensembl Acc Id:

ENSRNOP00000068775 ⟸ ENSRNOT00000077826

Ensembl Acc Id:

ENSRNOP00000027593 ⟸ ENSRNOT00000027593

Ensembl Acc Id:

ENSRNOP00000027518 ⟸ ENSRNOT00000027518

RefSeq Acc Id:	XP_038942723 ⟸ XM_039086795
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038942722 ⟸ XM_039086794
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038942721 ⟸ XM_039086793
- Peptide Label:	isoform X1
- UniProtKB:	Q9Z2M4 (UniProtKB/Swiss-Prot), A6HD86 (UniProtKB/TrEMBL), A0A8I6AJE6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000093315 ⟸ ENSRNOT00000104441

Ensembl Acc Id:

ENSRNOP00000080945 ⟸ ENSRNOT00000100345

Ensembl Acc Id:

ENSRNOP00000027439 ⟸ ENSRNOT00000027439

Ensembl Acc Id:

ENSRNOP00000095174 ⟸ ENSRNOT00000117914

Ensembl Acc Id:

ENSRNOP00000082618 ⟸ ENSRNOT00000098691

Ensembl Acc Id:

ENSRNOP00000095636 ⟸ ENSRNOT00000100008

RefSeq Acc Id:	XP_063125886 ⟸ XM_063269816
- Peptide Label:	isoform X1
- UniProtKB:	Q9Z2M4 (UniProtKB/Swiss-Prot), A0A8I6AJE6 (UniProtKB/TrEMBL), A6HD86 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000110670 ⟸ ENSRNOT00000165479

Protein Domains

EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Z2M4-F1-model_v2	AlphaFold	Q9Z2M4	1-292	view protein structure
AF-Q66H66-F1-model_v2	AlphaFold	Q66H66	1-446	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697069

Promoter ID:

EPDNEW_R7593

Type:

initiation region

Name:

Nme4_2

Description:

NME/NM23 nucleoside diphosphate kinase 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7594

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	15,459,886 - 15,459,946	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:71002	AgrOrtholog
BioCyc Gene	G2FUF-25732	BioCyc
Ensembl Genes	ENSRNOG00000032152	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00000050424	Ensembl
	ENSRNOG00000088984	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000027518	ENTREZGENE
	ENSRNOT00000027518.6	UniProtKB/Swiss-Prot
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7097883	IMAGE-MGC_LOAD
InterPro	DECR2-like	UniProtKB/Swiss-Prot
	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot
	SDR_fam	UniProtKB/Swiss-Prot
KEGG Report	rno:64461	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:91441	IMAGE-MGC_LOAD
NCBI Gene	64461	ENTREZGENE
PANTHER	PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]	UniProtKB/Swiss-Prot
	PTHR43296	UniProtKB/Swiss-Prot
Pfam	adh_short_C2	UniProtKB/Swiss-Prot
PhenoGen	Decr2	PhenoGen
PRINTS	GDHRDH	UniProtKB/Swiss-Prot
	SDRFAMILY	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000032152	RatGTEx
	ENSRNOG00000050424	RatGTEx
	ENSRNOG00000088984	RatGTEx
Superfamily-SCOP	SSF51735	UniProtKB/Swiss-Prot
UniProt	A0A8I6AJE6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLQ6_RAT	UniProtKB/TrEMBL
	A0ABK0M555_RAT	UniProtKB/TrEMBL
	A6HD86	ENTREZGENE, UniProtKB/TrEMBL
	DECR2_RAT	UniProtKB/Swiss-Prot
	Q6TXF6_RAT	UniProtKB/TrEMBL
	Q9Z2M4	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-12-15	Decr2	2,4-dienoyl-CoA reductase 2	Decr2	2,4-dienoyl CoA reductase 2, peroxisomal	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Decr2	2,4-dienoyl CoA reductase 2, peroxisomal	Decr2	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-07-09	Decr2	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to peroxisome

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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